Patents by Inventor Matthew Orr

Matthew Orr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190256530
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Application
    Filed: May 2, 2019
    Publication date: August 22, 2019
    Inventors: Daitao Chen, Matthew Orr, Jessica Sligar, Robert Jacobs, Jacob J. Plattner
  • Patent number: 10301329
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: May 28, 2019
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Daitao Chen, Matthew Orr, Jessica Sligar, Robert Jacobs, Jacob J. Plattner
  • Patent number: 10087211
    Abstract: This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: October 2, 2018
    Assignees: RESEARCH TRIANGLE INSTITUTE, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Scott P. Runyon, Michael Rogawski, Edgar Cook, John Kepler, Hernan Navarro, Rafal Kaminski, Matthew Orr
  • Publication number: 20170051008
    Abstract: This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage.
    Type: Application
    Filed: November 2, 2016
    Publication date: February 23, 2017
    Applicants: RESEARCH TRIANGLE INSTITUTE, The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Scott P. RUNYON, Michael ROGAWSKI, Edgar COOK, John KEPLER, Herman NAVARRO, Rafal KAMINSKI, Matthew ORR
  • Patent number: 9562612
    Abstract: A pressure control valve assembly includes a valve body including a valve opening that is characterized by an axis, a bonnet assembly removably attached to the valve body, wherein the bonnet assembly and the valve body collectively form a valve housing, and the valve housing defines a moving direction that is substantially perpendicular to the axis, a strongback assembly movably disposed in the valve housing and capable of moving in the moving direction defined by the valve housing, and a valve gate movably mounted on the strongback assembly and selectively sealing the valve opening, wherein the bonnet assembly, the strongback assembly and the valve gate are detachable from the valve body and from each other.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: February 7, 2017
    Assignee: HVA, LLC
    Inventor: Matthew Orr
  • Publication number: 20170009385
    Abstract: A monofilament is particularly suited for use as a component in an industrial textile such as a papermachine clothing (PMC) fabric. The monofilament is formed from a composition including more than 70 weight % to 99 weight % polyamide and from 1 weight % to less than 30 weight % polyphenylene ether.
    Type: Application
    Filed: July 7, 2015
    Publication date: January 12, 2017
    Inventors: VIKRAM DHENDE, BRIAN GOOD, MATTHEW ORR
  • Patent number: 9518080
    Abstract: This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: December 13, 2016
    Assignees: RESEARCH TRIANGLE INSTITUTE, The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Scott P Runyon, Michael Rogawski, Edgar Cook, John Kepler, Hernan Navarro, Rafal Kaminski, Matthew Orr
  • Publication number: 20160340369
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Application
    Filed: August 3, 2016
    Publication date: November 24, 2016
    Inventors: Daitao CHEN, Matthew Orr, Jessica Sligar, Robert Jacobs, Jacob J. Plattner
  • Patent number: 9493489
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Grant
    Filed: October 15, 2009
    Date of Patent: November 15, 2016
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Robert Jacobs, Matthew Orr, Stephen Wring, Daitao Chen, Huchen Zhou, Dazhong Ding, Yiqing Feng, Long Yi, Vincent S. Hernandez, Yong-Kang Zhang, Jacob J. Plattner
  • Patent number: 9440994
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. The exemplary compounds have the following formula: wherein X is selected from the group consisting of substituted phenyl, substituted or unsubstituted heteroaryl and unsubstituted cycloalkyl; R3a is selected from the group consisting of H, unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl; R3b is selected from the group consisting of H, unsubstituted C1 or C2 or C3 or C4 or C5 or C6 alkyl and unsubstituted C3 or C4 or C5 or C6 cycloalkyl; with the proviso that R3a and R3b, along with the atom to which they are attached, are optionally joined to form a 3 or 4 or 5 or 6 membered ring, with the proviso that R3a and R3b cannot both be H, or a salt thereof.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: September 13, 2016
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Daitao Chen, Matthew Orr, Jessica Sligar, Robert Jacobs, Jacob J. Plattner
  • Publication number: 20140094619
    Abstract: This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage.
    Type: Application
    Filed: August 23, 2013
    Publication date: April 3, 2014
    Applicants: US GOV BY THE SEC. OF DEPT. OF HEALTH & HUMAN SERV, RESEARCH TRIANGLE INSTITUTE
    Inventors: Scott P. RUNYON, Michael ROGAWSKI, Edgar COOK, John KEPLER, Hernan NAVARRO, Rafal KAMINSKI, Matthew ORR
  • Publication number: 20140042354
    Abstract: A pressure control valve assembly includes a valve body including a valve opening that is characterized by an axis, a bonnet assembly removably attached to the valve body, wherein the bonnet assembly and the valve body collectively form a valve housing, and the valve housing defines a moving direction that is substantially perpendicular to the axis, a strongback assembly movably disposed in the valve housing and capable of moving in the moving direction defined by the valve housing, and a valve gate movably mounted on the strongback assembly and selectively sealing the valve opening, wherein the bonnet assembly, the strongback assembly and the valve gate are detachable from the valve body and from each other.
    Type: Application
    Filed: July 12, 2013
    Publication date: February 13, 2014
    Applicant: HVA, LLC
    Inventor: Matthew ORR
  • Patent number: 8623911
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: January 7, 2014
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Robert T. Jacobs, Daitao Chen, Matthew Orr, Jacob J. Plattner
  • Patent number: 8575375
    Abstract: This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage.
    Type: Grant
    Filed: June 16, 2008
    Date of Patent: November 5, 2013
    Assignees: Research Triangle Institute, The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Scott P. Runyon, Michael A. Rogawski, John Kepler, Hernan Navarro, Rafal Kaminski, Matthew Orr, Kevin M. Cook
  • Publication number: 20130231304
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Application
    Filed: March 18, 2011
    Publication date: September 5, 2013
    Applicant: ANACOR PHARMACEUTICALS, INC.
    Inventors: Robert T. Jacobs, Daitao Chen, Matthew Orr, Jacob J. Plattner
  • Publication number: 20110207702
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Application
    Filed: October 15, 2009
    Publication date: August 25, 2011
    Applicant: Anacor Pharmaceuticals, Inc.
    Inventors: Robert Jacobs, Matthew Orr, Stephen Wring, Daitao Chen, Huchen Zhou, Dazhong Ding, Yiqing Feng, Long Yi, Vincent S. Hernandez, Yong-Kang Zhang, Jacob J. Plattner
  • Publication number: 20110190235
    Abstract: This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
    Type: Application
    Filed: August 6, 2010
    Publication date: August 4, 2011
    Applicant: Anacor Pharmaceuticals, Inc.
    Inventors: Daitao Chen, Matthew Orr, Jessica Sligar, Robert Jacobs, Jacob J. Plattner
  • Publication number: 20110092473
    Abstract: This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage.
    Type: Application
    Filed: June 16, 2008
    Publication date: April 21, 2011
    Applicants: Research Triangle Institute, US GOV BY THE SEC. OF DEPT. OF HEALTH & HUMAN SERV.
    Inventors: Scott P. Runyon, Michael Rogawski, Edgar Cook, Kevin M. Cook, John Kepler, Hernan Navarro, Rafal Kaminski, Matthew Orr
  • Patent number: 7830297
    Abstract: A method of classifying radar emitters includes the steps of: (a) receiving pulses from multiple radar emitters over a plurality of consecutive first time intervals; (b) identifying pulses in each of the plurality of consecutive first time intervals corresponding to one or more first pulse trains using a first algorithm and de-interleaving the identified pulses from the plurality of first time intervals; (c) associating received pulses not identified and de-interleaved using the first algorithm with a plurality of consecutive second time intervals; and (d) identifying further pulses in each of the plurality of consecutive second time intervals corresponding to one or more second pulse trains using a second algorithm different from the first algorithm and de-interleaving the identified further pulses from the pulses associated with the plurality of consecutive second time intervals. Each consecutive second time interval is formed from two or more consecutive first time intervals.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: November 9, 2010
    Assignee: ITT Manufacturing Enterprises, Inc.
    Inventors: Paul C. Wang, Matthew Orr, Mitchell Sparrow, Martin Apa
  • Patent number: 7397415
    Abstract: A method of classifying radar emitters includes the steps of: (a) receiving pulses from multiple radar emitters; (b) categorizing received pulses based on pulse data descriptors (PDWs); (c) forming clusters of received pulses based on the PDWs; and (d) de-interleaving pulses from the cluster using one of a differential time of arrival (DTOA) histogram technique, a spectrum estimation technique, or a Hough transform technique. Step (a) includes receiving the pulses during a predetermined time interval and storing the received pulses as a snapshot representing the pulses present during the predetermined time interval.
    Type: Grant
    Filed: February 2, 2006
    Date of Patent: July 8, 2008
    Assignee: ITT Manufacturing Enterprises, Inc.
    Inventors: Paul C. Wang, Matthew Orr, Mitchell Sparrow, Martin Apa