Patents by Inventor Matthew P. Horning

Matthew P. Horning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10132743
    Abstract: Disclosed is a low-cost, portable photo thermal spectroscopy (PTS) reader for use in detecting the presence of diseases in the bodily fluid of affected patients. The PTS reader is designed to be durable, easy to use and provide readings from the Lateral Flow Assay (LFA) with rapid results. Also provided are methods of use.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: November 20, 2018
    Assignees: General Electric Company, Tokitae LLC
    Inventors: Ralf Lenigk, Mark Marshall Meyers, Victor Petrovich Ostroverkhov, Timothy Toepfer, Keith Michael Looney, Terry Lee Saunders, Kevin Paul Flood Nichols, Matthew P. Horning, Benjamin K. Wilson, Daniel Keith Connors, David Gasperino
  • Patent number: 10094823
    Abstract: Embodiments disclosed herein are directed to a photothermal spectroscopy assay reader including a light source configured to emit light in the red range of the light spectrum. Methods of operating such photothermal spectroscopy assay readers are also disclosed. Assay kits including a lateral flow assay and a photothermal spectroscopy assay reader configured to read the photothermal spectroscopy assay reader are also disclosed.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: October 9, 2018
    Assignee: TOKITAE LLC
    Inventors: Matthew P. Horning, Kevin Paul Flood Nichols, Benjamin K. Wilson
  • Patent number: 10061972
    Abstract: Embodiments disclosed herein are directed to systems and methods for determining a presence and an amount of an analyte in a biological sample. The systems and methods for determining the presence of an analyte utilize a plurality of images of a sample slide including multiple fields-of-view having multiple focal planes therein. The systems and methods utilize algorithms configured to balance the color and grayscale intensity of the plurality of images and based thereon determine if the plurality of images contain the analyte therein.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: August 28, 2018
    Assignee: TOKITAE LLC
    Inventors: Cary Richard Champlin, Charles Delahunt, Matthew P. Horning, Liming Hu, Shawn Keith McGuire, Courosh Mehanian, Clay Matthew Thompson, Benjamin K. Wilson
  • Patent number: 9836839
    Abstract: Embodiments disclosed herein are directed to systems and methods for determining a presence and an amount of an analyte in a biological sample. The systems and methods for determining the presence of an analyte utilize a plurality of images of a sample slide including multiple fields-of-view having multiple focal planes therein. The systems and methods utilize algorithms configured to color and grayscale intensity balance the plurality of images and based thereon determine if the plurality of images contain the analyte therein.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: December 5, 2017
    Assignee: TOKITAE LLC
    Inventors: Cary Richard Champlin, Charles Delahunt, Matthew P. Horning, Liming Hu, Shawn Keith McGuire, Courosh Mehanian, Clay Matthew Thompson, Benjamin K. Wilson
  • Publication number: 20170211982
    Abstract: Disclosed is a low-cost, portable photo thermal spectroscopy (PTS) reader for use in detecting the presence of diseases in the bodily fluid of affected patients. The PTS reader is designed to be durable, easy to use and provide readings from the Lateral Flow Assay (LFA) with rapid results. Also provided are methods of use.
    Type: Application
    Filed: July 22, 2016
    Publication date: July 27, 2017
    Inventors: Ralf Lenigk, Mark Marshall Meyers, Victor Petrovich Ostroverkhov, Timothy Toepfer, Keith Michael Looney, Terry Lee Saunders, Kevin Paul Flood Nichols, Matthew P. Horning, Benjamin K. Wilson, Daniel Keith Connors, David Gasperino
  • Publication number: 20170161545
    Abstract: Embodiments disclosed herein are directed to systems and methods for determining a presence and an amount of an analyte in a biological sample. The systems and methods for determining the presence of an analyte utilize a plurality of images of a sample slide including multiple fields-of-view having multiple focal planes therein. The systems and methods utilize algorithms configured to balance the color and grayscale intensity of the plurality of images and based thereon determine if the plurality of images contain the analyte therein.
    Type: Application
    Filed: February 15, 2017
    Publication date: June 8, 2017
    Inventors: Cary Richard Champlin, Charles Delahunt, Matthew P. Horning, Liming Hu, Shawn Keith McGuire, Courosh Mehanian, Clay Matthew Thompson, Benjamin K. Wilson
  • Patent number: 9625385
    Abstract: Embodiments disclosed herein are directed to photothermal spectroscopy apparatuses and systems for offset synchronous testing of flow assays. Methods of using and operating such photothermal spectroscopy systems are also disclosed.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: April 18, 2017
    Assignee: TOKITAE LLC
    Inventors: David Gasperino, Matthew P. Horning, Kevin Paul Flood Nichols, Phil Rutschman, Benjamin K. Wilson, Ozgur Emek Yildirim
  • Patent number: 9524417
    Abstract: Systems, devices, and methods are described for providing a monitor or treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: December 20, 2016
    Assignee: Tokitae LLC
    Inventors: Matthew R. Behrend, Michael C. Hegg, Matthew P. Horning, Benjamin K. Wilson
  • Publication number: 20160350914
    Abstract: Embodiments disclosed herein are directed to systems and methods for determining a presence and an amount of an analyte in a biological sample. The systems and methods for determining the presence of an analyte utilize a plurality of images of a sample slide including multiple fields-of-view having multiple focal planes therein. The systems and methods utilize algorithms configured to color and grayscale intensity balance the plurality of images and based thereon determine if the plurality of images contain the analyte therein.
    Type: Application
    Filed: May 13, 2016
    Publication date: December 1, 2016
    Inventors: Cary Richard Champlin, Charles Delahunt, Matthew P. Horning, Liming Hu, Shawn Keith McGuire, Courosh Mehanian, Clay Matthew Thompson, Benjamin K. Wilson
  • Patent number: 9453996
    Abstract: Devices and methods for preparing and assessing a liquid sample are described which include: a microfluidic microscopy device including an absorbent structure including at least one dry dye for a liquid and configured to convey a polar liquid from a first end of the absorbent structure through the at least one dry dye for a liquid to a second end of the absorbent structure, a support structure positioned adjacent to a first surface of the absorbent structure, a lid structure positioned adjacent to a second surface of the absorbent structure, and a clamping structure positioned to maintain a relative position of the support structure and the lid structure to form a tapered internal chamber adjacent to the second end of the absorbent structure.
    Type: Grant
    Filed: October 23, 2013
    Date of Patent: September 27, 2016
    Assignee: Tokitae LLC
    Inventors: Charles Delahunt, David Gasperino, Matthew P. Horning, Kevin P. F. Nichols, Benjamin K. Wilson
  • Publication number: 20160245748
    Abstract: Embodiments disclosed herein are directed to photothermal spectroscopy apparatuses and systems for offset synchronous testing of flow assays. Methods of using and operating such photothermal spectroscopy systems are also disclosed.
    Type: Application
    Filed: February 24, 2015
    Publication date: August 25, 2016
    Inventors: David Gasperino, Matthew P. Horning, Kevin Paul Flood Nichols, Phil Rutschman, Benjamin K. Wilson, Ozgur Emek Yildirim
  • Publication number: 20160216260
    Abstract: Embodiments disclosed herein are directed to a photothermal spectroscopy assay reader including a light source configured to emit light in the red range of the light spectrum. Methods of operating such photothermal spectroscopy assay readers are also disclosed. Assay kits including a lateral flow assay and a photothermal spectroscopy assay reader configured to read the photothermal spectroscopy assay reader are also disclosed.
    Type: Application
    Filed: January 23, 2015
    Publication date: July 28, 2016
    Inventors: Matthew P. Horning, Kevin Paul Flood Nichols, Benjamin K. Wilson
  • Patent number: 9310289
    Abstract: Systems, devices, and methods are described that modulate a specimen-background dark-field micrograph contrast.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: April 12, 2016
    Assignee: Tokitae LLC
    Inventors: Matthew R. Behrend, Michael C. Hegg, Matthew P. Horning, Benjamin K. Wilson
  • Patent number: 9044141
    Abstract: Systems, devices, and methods are described for providing a monitor or treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: June 2, 2015
    Assignee: Tokitae LLC
    Inventors: Matthew R. Behrend, Michael C. Hegg, Matthew P. Horning, Benjamin K. Wilson
  • Publication number: 20150111216
    Abstract: Devices and methods for preparing and assessing a liquid sample are described which include: a microfluidic microscopy device including an absorbent structure including at least one dry dye for a liquid and configured to convey a polar liquid from a first end of the absorbent structure through the at least one dry dye for a liquid to a second end of the absorbent structure, a support structure positioned adjacent to a first surface of the absorbent structure, a lid structure positioned adjacent to a second surface of the absorbent structure, and a clamping structure positioned to maintain a relative position of the support structure and the lid structure to form a tapered internal chamber adjacent to the second end of the absorbent structure.
    Type: Application
    Filed: October 23, 2013
    Publication date: April 23, 2015
    Inventors: Charles Delahunt, David Gasperino, Matthew P. Horning, Kevin P. F. Nichols, Benjamin K. Wilson
  • Publication number: 20140362302
    Abstract: Systems, devices, and methods are described that modulate a specimen-background dark-field micrograph contrast.
    Type: Application
    Filed: August 22, 2014
    Publication date: December 11, 2014
    Applicant: TOKITAE LLC
    Inventors: Matthew R. Behrend, Michael C. Hegg, Matthew P. Horning, Benjamin K. Wilson
  • Patent number: 8854622
    Abstract: Systems, devices, and methods are described that modulate a specimen-background dark-field micrograph contrast.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: October 7, 2014
    Inventors: Matthew R. Behrend, Michael C. Hegg, Matthew P. Horning, Benjamin K. Wilson
  • Publication number: 20140294280
    Abstract: Systems, devices, and methods are described for providing a monitor or treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.
    Type: Application
    Filed: June 18, 2014
    Publication date: October 2, 2014
    Inventors: Matthew R. Behrend, Michael C. Hegg, Matthew P. Horning, Benjamin K. Wilson
  • Patent number: 8840536
    Abstract: Systems, devices, and methods are described for providing a monitor/treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.
    Type: Grant
    Filed: February 10, 2010
    Date of Patent: September 23, 2014
    Inventors: Michael C. Hegg, Matthew P. Horning, Jordin T. Kare, Nathan P. Myhrvold, Clarence T. Tegreene, Benjamin K. Wilson, Lowell L. Wood, Jr.
  • Patent number: 8781184
    Abstract: Systems, devices, and methods are described for providing a monitor or treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: July 15, 2014
    Assignee: Tokitae LLC
    Inventors: Matthew R. Behrend, Michael C. Hegg, Matthew P. Horning, Benjamin K. Wilson