Patents by Inventor Matthew P. Smith

Matthew P. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11964989
    Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: April 23, 2024
    Assignees: Mirati Therapeutics, Inc., Array BioPharma Inc.
    Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
  • Publication number: 20240101553
    Abstract: The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
    Type: Application
    Filed: August 4, 2023
    Publication date: March 28, 2024
    Inventors: Matthew Arnold MARX, James Gail CHRISTENSEN, Christopher Ronald SMITH, James F. BLAKE, Laurence E. BURGESS, Mark Joseph CHICARELLI, Adam COOK, Jay Bradford FELL, John P. FISCHER, Macedonio J. MEJIA, Martha E. RODRIGUEZ, Pavel SAVECHENKOV, Tony P. TANG, Guy P.A. VIGERS
  • Patent number: 11938738
    Abstract: In some examples, an apparatus can include a syringe body including an electrical interface at a side surface of the syringe body, an interface at an end of the syringe body including an output at a distal surface of the syringe body, a print material particles reservoir located in the syringe body, and a structure to adapt a volume of the print material particles reservoir to move print material particles out of the print material particles reservoir through the output, where in response to the volume adapting structure moving from a first position to a second position, a signal is transmitted by the electrical interface.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: March 26, 2024
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Andrew P. Chick, Kenneth K. Smith, Jiwon Moon, Minul Lee, Matthew James Storey, An Tran, Bennett Alexander Nadeau, Zackary Thomas Hickman
  • Patent number: 6336457
    Abstract: Tube securing devices and method of using them are disclosed for immobilizing an endotracheal tube or the like in a body cavity such as in an intubated position. The device includes an elongated tube grasping arrangement having a ribbon securing device for helping to maintain the position of the tube grasping device in place. The tube grasping device includes a gripping portion disposed between its opposite ends to help limit sliding movement relative to the tube grasping assembly.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: January 8, 2002
    Inventors: Michael S. Hudson, Matthew P. Smith, Douglas A. Moriarty