Patents by Inventor Matthew Parris

Matthew Parris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20240374601
    Abstract: Disclosed herein is a method of treating ovarian cancer by administering to the subject a solid pharmaceutical composition comprising 8-cyclopentyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carbonitrile or a pharmaceutically-acceptable salt thereof, alone or in combination with a second agent such as letrozole.
    Type: Application
    Filed: May 15, 2024
    Publication date: November 14, 2024
    Inventors: Steven M. Fruchtman, Matthew Parris, Mark S. Gelder
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20240374600
    Abstract: Disclosed herein is a method of treating endometrial cancer by administering to the subject a solid pharmaceutical composition comprising 8-cyclopentyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carbonitrile or a pharmaceutically-acceptable salt thereof, alone or in combination with a second agent such as letrozole.
    Type: Application
    Filed: May 15, 2024
    Publication date: November 14, 2024
    Inventors: Steven M. Fruchtman, Matthew Parris, Mark S. Gelder
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20240366610
    Abstract: Disclosed herein is a method of treating a cancer in a subject in need thereof, the method comprising administering to the subject a therapeutically-effective amount of a first compound, or a pharmaceutically-acceptable salt or zwitterion thereof, and a therapeutically-effective amount of a second compound, or a pharmaceutically-acceptable salt thereof.
    Type: Application
    Filed: March 19, 2024
    Publication date: November 7, 2024
    Inventors: Steven Fruchtman, Mark S. Gelder, Matthew Parris
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20240299326
    Abstract: Disclosed herein is a method of treating a squamous cell carcinoma (SCC), a SCC associated with a disease, for example, recessive dystrophic epidermolysis bullosa (RDEB). The method of the disclosure describes administering a therapeutically-effective amount of (E)-2-(5-((2,4,6-trimethoxystyrylsulfonyl)methyl)-2-methoxyphenylamino)acetic acid, or a pharmaceutically-acceptable salt or zwitterion thereof, and derivatives thereof.
    Type: Application
    Filed: February 9, 2024
    Publication date: September 12, 2024
    Inventors: Steven Fruchtman, Matthew Parris
  • METHODS AND COMPOSITIONS FOR TREATING CANCER
    Publication number: 20240269099
    Abstract: RAS proteins are frequently mutated in human cancers. Disclosed herein are compounds that disrupt RAS effectors and inhibits Ras/Raf/MEK/ERK pathway signaling. Further disclosed herein are methods of using compounds in combination with checkpoint inhibitors to treat cancer.
    Type: Application
    Filed: December 15, 2023
    Publication date: August 15, 2024
    Inventors: Steven Fruchtman, Matthew Parris
  • Glufosfamide Combination Therapies for Cancer
    Publication number: 20130281386
    Abstract: The invention provides compositions and methods for treating cancer with glufosfamide in combination with an inhibitor of sodium-glucose transporter type 2 (SGLT2) to block the uptake of glucose in the proximal tubules of the kidneys to decrease renal toxicity. The invention relates to the fields of biomedicine, pharmacology, and molecular biology.
    Type: Application
    Filed: August 30, 2012
    Publication date: October 24, 2013
    Applicant: Eleison Pharmaceuticals LLC
    Inventors: Forrest H. Anthony, Edwin J. Thomas, Matthew Parris