Patents by Inventor Matthew Paul Grote

Matthew Paul Grote has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9630956
    Abstract: The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: wherein the variables are as defined herein.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: April 25, 2017
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Jean-Damien Charrier, Hayley Marie Binch, Dennis James Hurley, Thomas Cleveland, Pramod Joshi, Lev Tyler Dewey Fanning, Joanne Pinder, Michael O'Donnell, Anisa Nizarali Virani, Ronald Marcellus Alphonsus Knegtel, Steven John Durrant, Stephen Clinton Young, Pierre-Henri Storck, David Kay, Philip Michael Reaper, Matthew Paul Grote