Abstract: A method and system is provided that manages events involving an individual's digital assets and/or external services that the individual interfaces with using external service credentials. The method and system allow the individual to securely store digital assets and external service credentials used to login to external services. The method and system further allow the individual to create a plan of actions to be executed on specified dates, where the actions involve one or more of the individual's digital assets and/or involve one or more external services that the individual interfaces with using one or more external service credentials. The plan of actions takes the format of a timeline that includes one or more timeline events, where an action and a date are associated with a timeline event.

Abstract: A method and system is provided that manages events involving an individual's digital assets and/or external services that the individual interfaces with using external service credentials. The method and system allow the individual to securely store digital assets and external service credentials used to login to external services. The method and system further allow the individual to create a plan of actions to be executed on specified dates, where the actions involve one or more of the individual's digital assets and/or involve one or more external services that the individual interfaces with using one or more external service credentials. The plan of actions takes the format of a timeline that includes one or more timeline events, where an action and a date are associated with a timeline event.

Abstract: A method for the preparation of a lactam compound of formula ##STR1## wherein R'.sub.1 and R".sub.1 independently are acyl or aroyl, or taken together form an optionally substituted methylene, and G.sub.1 is hydrogen or an amino protecting group, comprising oxidizing a bis O-protected 1R-2-azadihydroxybicyclo-?2.2.1!heptane compound of formula ##STR2## with about 0.1 mol % to about 1 mol % of RuO.sub.2 or hydrate thereof in the presence of about 3 equivalents of an oxidant to form the lactam compound with an enantiomeric excess of greater than or equal to about 95%.

Abstract: A method for the preparation of a compound of formula ##STR1## wherein R is hydrogen or, respectively, a group of formula ##STR2## R.sub.1 is alkyl; Ar is optionally substituted aryl; andR.sub.3' and R.sub.3" are hydrogen, alkyl or phenyl, or R.sub.3' and R.sub.3" taken together with the carbon atom to which they are attached form cycloalkyl, or salt thereof, comprising acid facilitated acetalizing or ketalizing of a compound of formula ##STR3## wherein R.sub.3' and R.sub.3" are as defined above, and R.sub.4' and R.sub.4" are alkoxy, or taken together with the carbon atom to which they are attached form carbonyl, with a compound of formula ##STR4## wherein * represents an R chirality;R, R.sub.1 and Ar are as defined above, or salt thereof in isopropanol.

Abstract: A process is described for the preparation of a compound of formula (IX) from 4-hydroxybutyl 3-pyridyl ketone. The compound of formula (IX) is an intermediate useful in the preparation of (1R,2R)-2-(3-pyridyl)-N-alkyl-tetrahydro-2H-thiopyran-2-carbothioamide 1-oxides which possess useful pharmaceutical properties, for example anti-hypertensive properties.

Abstract: A method according to the invention is directed to the preparation of a 2-azadihydroxybicyclo?2.2.1!heptane compound of formula ##STR1## wherein * represents an R chirality, *' represents an S chirality, R is hydrogen or, respectively, a group of formula ##STR2## wherein R.sub.1 is alkyl and Ar is optionally substituted aryl, comprising bishydroxylating a bicyclo?2.2.1!heptene compound of formula ##STR3## wherein *, *' and R are as previously defined, in the presence of about 0.1 mol to about 5 mol % of a metal osmate compound or about 0.06 mol % to about 0.07 mol % osmium tetroxide, and an oxidizing agent capable of regenerating osmium tetroxide.The invention is also directed to the treatment of the (1R) diastereomer of the 2-azadihydroxybicyclo?2.2.1!heptane compound (I) wherein R is a group of formula II with L-tartaric acid, and the L-tartaric acid salt product thereof. Furthermore, the invention is directed to using the (1R) diastereomer of the 2-azadihydroxybicyclo?2.2.