Abstract: In accordance with some embodiments, systems, methods, and media for automatically localizing and diagnosing thyroid nodules are provided. In some embodiments, a system for automatically diagnosing thyroid nodules comprises: an ultrasound machine; and a processor programmed to: receive a B-mode ultrasound of a thyroid from the ultrasound machine; provide the B-mode ultrasound to a classification model trained to automatically segment B-mode ultrasound; receive an output indicating which portions of the B-mode ultrasound correspond to a nodule; provide at least a portion of the B-mode ultrasound corresponding to the nodule to a second classification model trained to automatically classify thyroid nodules based B-mode, color Doppler, and shear wave elastography ultrasound; and receive, from the second trained classification model, an output indicative of the likelihood that the nodule is malignant.

Abstract: In accordance with some embodiments, systems, methods, and media for automatically localizing and diagnosing thyroid nodules are provided. In some embodiments, a system for automatically diagnosing thyroid nodules comprises: an ultrasound machine; and a processor programmed to: receive a B-mode ultrasound of a thyroid from the ultrasound machine; provide the B-mode ultrasound to a classification model trained to automatically segment B-mode ultrasound; receive an output indicating which portions of the B-mode ultrasound correspond to a nodule; provide at least a portion of the B-mode ultrasound corresponding to the nodule to a second classification model trained to automatically classify thyroid nodules based B-mode, color Doppler, and shear wave elastography ultrasound; and receive, from the second trained classification model, an output indicative of the likelihood that the nodule is malignant.

Abstract: A tissue displacement apparatus used during a tissue ablation procedure is provided. In some configurations, the tissue displacement apparatus is configured to displace tissue within a patient and thermally isolate the displaced tissue.

Abstract: A cryoablation procedure at a surgery site is planned and simulated. One or more pre-procedure planning images of the surgery site are displayed on a user interface. Positioning of one or more virtual cryoprobes relative to the one or more pre-procedure planning images on the user interface is facilitated. Properties of the one or more virtual cryoprobes are selectable. Ice ball formation at the surgery site is then simulated based on the position and properties of the virtual cryoprobes. The simulated ice ball formation is based at least in part on tissue properties of the surgery site at each image unit of the one or more pre-procedure planning images. Boundaries of the simulated ice ball formation on the one or more pre-procedure planning images are then displayed.

Abstract: A method for generating colonography images for colorectal screening of a patient. The patient is administered an amount of radiopaque stool marker which will enable stool present in the patient's colon to be distinguished from soft tissue. The patient's colon is imaged after the stool marker has been administered to generate colonography images. Preparation of the colon is simulated by processing the colonography images to remove marked stool before the images are observed during a diagnosis session.

Abstract: A method for generating colonography images for colorectal screening of a patient. The patient is administered an amount of radiopaque stool marker which will enable stool present in the patient's colon to be distinguished from soft tissue. The patient's colon is imaged after the stool marker has been administered to generate colonography images. Preparation of the colon is simulated by processing the colonography images to remove marked stool before the images are observed during a diagnosis session.

Abstract: A method for generating colonography images for colorectal screening of a patient. The patient is administered an amount of radiopaque stool marker which will enable stool present in the patient's colon to be distinguished from soft tissue. The patient's colon is imaged after the stool marker has been administered to generate colonography images. Preparation of the colon is simulated by processing the colonography images to remove marked stool before the images are observed during a diagnosis session.

Abstract: A method for generating colonography images for colorectal screening of a patient. The patient is administered an amount of radiopaque stool marker which will enable stool present in the patient's colon to be distinguished from soft tissue. The patient's colon is imaged after the stool marker has been administered to generate colonography images. Preparation of the colon is simulated by processing the colonography images to remove marked stool before the images are observed during a diagnosis session.

Abstract: A method is disclosed for preparing water soluble protein polymer conjugates which stabilize the protein so as to retain functional properties in a hostile environment. The method comprises covalently bonding the polymer to the protein through at least three linkers which linkers have three or more hydroxyl groups. The protein is conjugated at lysines or arginines.

Abstract: An improvement in enzyme linked immunoassays is disclosed wherein the enzyme is in the form of a water soluble polymer saccharide conjugate which is stable in hostile environments. The conjugate comprises the enzyme which is linked to the polymer at multiple points through saccharide linker groups.

Abstract: A method of producing glassy carbon containing metal particles includes two steps. The first step is providing a metal complexed to a molecule which can cross-link to form glassy carbon. The molecule is heated so that the molecule cross-links to form glassy carbon containing metal particles. The glassy carbon can be incorporated into an electrode for use in an electrochemical cell.

Abstract: A method is disclosed for synthesizing peptides using water soluble enzyme polymer conjugates. The method comprises catalyzing the peptide synthesis with enzyme which has been covalently bonded to a polymer through at least three linkers which linkers have three or more hydroxyl groups. The enzyme is conjugated at lysines or arginines.

Abstract: This invention is directed to water soluble protein polymer conjugates which are stabile in hostile environments. The conjugate comprises a protein which is linked to an acrylic polymer at multiple points through saccharide linker groups.

Abstract: Glassy carbons including a dispersion of metal particles having a small particle size, their synthesis, and their use in electrochemical cells are described.

Abstract: A separation process includes producing low temperature glassy carbon from an aromatic oligomeric precursor with acetylene groups and using the resultant glassy carbon as the stationary phase in a separation process. Glassy carbon with preselected selectivity and retention characteristics can be generated by controlling the temperature of which the glassy carbon is processed.