Patents by Inventor Matthew R. Kaser

Matthew R. Kaser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transcription factor regulatory protein
    Publication number: 20020102615
    Abstract: The invention provides a mammalian nucleic acid sequence and fragments thereof. It also provides for the use of these nucleic acid sequences in a model system for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with expression of the mammalian nucleic acid sequence. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid sequence.
    Type: Application
    Filed: April 17, 2001
    Publication date: August 1, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Matthew R. Kaser, Mariah R. Baughn
  • Polycyclic aromatic hydrocarbon induced molecules
    Publication number: 20020091247
    Abstract: The invention provides novel nucleic acid molecules and encoded proteins associated with response to polycyclic aromatic hydrocarbon exposure. The invention also provides expression vectors, host cells, and antibodies. The invention also provides methods for screening or purifying ligands and diagnosing, treating or preventing disorders associated with polycyclic aromatic hydrocarbon exposure.
    Type: Application
    Filed: April 18, 2001
    Publication date: July 11, 2002
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Matthew R. Kaser, Yalda Azimzai, Henry Yue
  • Human presenilin variant
    Publication number: 20020082211
    Abstract: The invention provides a cDNA which encodes human presenilin variant. It also provides for the use of the cDNA and protein in the diagnosis, prognosis, treatment and evaluation of therapies for cancer or neurodegenerative or immune disorders. The invention further provides vectors and host cells for the production of the protein and transgenic model systems.
    Type: Application
    Filed: June 29, 2001
    Publication date: June 27, 2002
    Inventors: Chandra Arvizu, Lynn E. Murry, Matthew R. Kaser
  • Mammalian toxicological response markers
    Patent number: 6372431
    Abstract: The present invention relates to mammalian nucleic acid and protein molecules comprising a plurality of nucleic acid and protein molecules. The mammalian nucleic acid molecules can be used as hybridizable array elements in a microarray in diagnostic and therapeutic applications including detecting metabolic and toxicological responses, and in monitoring drug mechanism of action. The protein molecules can be used in a pharmaceutical composition. The present invention also relates to methods for screening compounds and therapeutics for metabolic responses indicative of a toxic compound or molecule.
    Type: Grant
    Filed: November 19, 1999
    Date of Patent: April 16, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Mary Jane Cunningham, Gary B. Zweiger, Matthew R. Kaser, Scott R. Panzer, Jeffrey J. Seilhamer, Henry Yue, Mariah R. Baughn, Yalda Azimzai, Preeti Lal
  • Tapasin-like protein
    Patent number: 6322977
    Abstract: The invention provides a mammalian nucleic acid sequence and fragments thereof. It also provides for the use of the nucleic acid sequence for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with gene expression and for the production of a model system. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid sequence.
    Type: Grant
    Filed: April 14, 1999
    Date of Patent: November 27, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Preeti Lal, Matthew R. Kaser, Mariah R. Baughn
  • Human membrane-spanning proteins
    Publication number: 20010025098
    Abstract: The invention provides a human membrane spanning proteins (MSPs) and polynucleotides which identify and encode MSPs. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of MSPs.
    Type: Application
    Filed: March 30, 2001
    Publication date: September 27, 2001
    Applicant: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Olga Bandman, Preeti Lal, Jennifer L. Hillman, Henry Yue, Neil C. Corley, Karl J. Guegler, Matthew R. Kaser, Mariah R. Baughn, Purvi Shah
  • Phospholipid transfer protein
    Patent number: 6287786
    Abstract: The invention provides a mammalian nucleic acid molecule and fragments thereof. It also provides for the use of the nucleic acid molecule for the characterization, diagnosis, or treatment of conditions, diseases and disorders associated with gene expression and for the production of a model system. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid molecule.
    Type: Grant
    Filed: July 31, 2000
    Date of Patent: September 11, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Matthew R. Kaser, Jennifer L. Hillman, Mariah R. Baughn
  • Polycyclic aromatic hydrocarbon induced molecules
    Patent number: 6262247
    Abstract: The invention provides novel nucleic acid molecules and encoded proteins associated with response to polycyclic aromatic hydrocarbon exposure. The invention also provides expression vectors, host cells, and antibodies. The invention also provides methods for screening or purifying ligands and diagnosing, treating or preventing disorders associated with polycyclic aromatic hydrocarbon exposure.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: July 17, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Matthew R. Kaser, Yalda Azimzai, Henry Yue
  • Lipid metabolism transcription factor
    Patent number: 6245526
    Abstract: The invention provides a mammalian nucleic acid sequence and fragments thereof. It also provides for the use of these nucleic acid sequences in a model system for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with expression of the mammalian nucleic acid sequence. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid sequence.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: June 12, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Matthew R. Kaser, Mariah R. Baughn
  • Purified nucleic acid encoding transcription factor regulatory protein
    Patent number: 6242185
    Abstract: The invention provides a mammalian nucleic acid sequence and fragments thereof. It also provides for the use of these nucleic acid sequences in a model system for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with expression of the mammalian nucleic acid sequence. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid sequence.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: June 5, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Matthew R. Kaser, Mariah R. Baughn
  • Molecules expressed in hippocampus
    Patent number: 6222027
    Abstract: The invention provides novel developmentally-regulated hippocampal genes and polypeptides encoded by those genes. The invention also provides expression vectors, host cells, and antibodies. The invention also provides methods for diagnosing, treating or preventing diseases associated with hippocampus.
    Type: Grant
    Filed: May 17, 1999
    Date of Patent: April 24, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Matthew R. Kaser, Preeti Lal, Henry Yue, Y. Tom Tang, Mariah R. Baughn, Yalda Azimzai
  • Phospholipid transfer protein
    Patent number: 6168933
    Abstract: The invention provides a mammalian nucleic acid molecule and fragments thereof. It also provides for the use of the nucleic acid molecule for the characterization, diagnosis, evaluation, treatment, or prevention of conditions, diseases and disorders associated with gene expression and for the production of a model system. The invention additionally provides expression vectors and host cells for the production of the protein encoded by the mammalian nucleic acid molecule.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: January 2, 2001
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Matthew R. Kaser, Jennifer L. Hillman, Mariah R. Baughn
  • Human preprotachykinin B
    Patent number: 6008194
    Abstract: The invention provides a human preprotachykinin B (PPT-B) and polynucleotides which identify and encode PPT-B. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PPT-B.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: December 28, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Matthew R. Kaser
  • Human preprotachykinin B
    Patent number: 5985606
    Abstract: The invention provides a human preprotachykinin B (PPT-B) and polynucleotides which identify and encode PPT-B. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PPT-B.
    Type: Grant
    Filed: June 19, 1997
    Date of Patent: November 16, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Matthew R. Kaser
  • Human growth-related CDC10 homolog
    Patent number: 5952214
    Abstract: The invention provides a human growth-related CDC10 homolog (GR-SEP) and polynucleotides which identify and encode GR-SEP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of GR-SEP.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: September 14, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Matthew R. Kaser, Preete Mathur
  • Human growth-related CDC10 homolog
    Patent number: 5849556
    Abstract: The invention provides a human growth-related CDC10 homolog (GR-SEP) and polynucleotides which identify and encode GR-SEP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of GR-SEP.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: December 15, 1998
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Matthew R. Kaser, Preete Mathur