Patents by Inventor Matthew R. Larson

Matthew R. Larson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210280268
    Abstract: The present invention is an accelerated conformational sampling method for predicting target peptide and protein structures comprising a process of determining energy minimized synthetic templates using a simple system for modeling individual molecular bonds within the subject peptide or protein. Use of these synthetic templates greatly reduces the computational resources necessary for optimally determining structural features of the target peptide or protein. The present invention also provides methods for rapid and efficient analysis of the effect of mutations on target peptides and proteins.
    Type: Application
    Filed: May 20, 2021
    Publication date: September 9, 2021
    Applicant: DNASTAR, INC.
    Inventors: Frederick R. BLATTNER, Steven J. DARNELL, Matthew R. LARSON, Amanda E. MITCHELL, John L. SCHROEDER
  • Patent number: 11031094
    Abstract: The present invention is an accelerated conformational sampling method for predicting target peptide and protein structures comprising a process of determining energy minimized synthetic templates using a simple system for modeling individual molecular bonds within the subject peptide or protein. Use of these synthetic templates greatly reduces the computational resources necessary for optimally determining structural features of the target peptide or protein. The present invention also provides methods for rapid and efficient analysis of the effect of mutations on target peptides and proteins.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: June 8, 2021
    Assignee: DNASTAR, INC.
    Inventors: Frederick R. Blattner, Steven J. Darnell, Matthew R. Larson, Amanda E. Mitchell, John L. Schroeder
  • Patent number: 10293958
    Abstract: A system and method for detecting and removing moisture in a vehicle such as a commercial aircraft is disclosed. Moisture detection sensors are mounted in areas of the vehicle which are inaccessible during use. The sensors output a signal when moisture is present in an adjacent area. Conduits are installed in the vehicle with a first end adjacent to an associated moisture detection sensors. A dry gas supply unit that is separate from the vehicle is coupled to a second end of each conduits to selectively supply dry gas thereto. The dry gas supply unit selectively supplies dry gas to the second end of each conduit when an associated moisture detection sensor outputs a signal indicating that moisture is present in the adjacent area. The moisture detection sensors are preferably passive and only output a signal upon receipt of an external interrogation signal from the dry gas supply unit controller.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: May 21, 2019
    Assignee: THE BOEING COMPANY
    Inventors: Joseph A. Bolton, Matthew R. Larson, Sarah E. Zayic, Niki Lewis
  • Publication number: 20180260517
    Abstract: The present invention is an accelerated conformational sampling method for predicting target peptide and protein structures comprising a process of determining energy minimized synthetic templates using a simple system for modeling individual molecular bonds within the subject peptide or protein. Use of these synthetic templates greatly reduces the computational resources necessary for optimally determining structural features of the target peptide or protein. The present invention also provides methods for rapid and efficient analysis of the effect of mutations on target peptides and proteins.
    Type: Application
    Filed: July 15, 2016
    Publication date: September 13, 2018
    Applicant: DNASTAR, INC.
    Inventors: Frederick R. BLATTNER, Steven J. DARNELL, Matthew R. LARSON, Amanda E. MITCHELL, John L. SCHROEDER
  • Publication number: 20180251235
    Abstract: A system and method for detecting and removing moisture in a vehicle such as a commercial aircraft is disclosed. Moisture detection sensors are mounted in areas of the vehicle which are inaccessible during use. The sensors output a signal when moisture is present in an adjacent area. Conduits are installed in the vehicle with a first end adjacent to an associated moisture detection sensors. A dry gas supply unit that is separate from the vehicle is coupled to a second end of each conduits to selectively supply dry gas thereto. The dry gas supply unit selectively supplies dry gas to the second end of each conduit when an associated moisture detection sensor outputs a signal indicating that moisture is present in the adjacent area. The moisture detection sensors are preferably passive and only output a signal upon receipt of an external interrogation signal from the dry gas supply unit controller.
    Type: Application
    Filed: March 1, 2017
    Publication date: September 6, 2018
    Inventors: Joseph A. Bolton, Matthew R. Larson, Sarah E. Zayic, Niki Lewis