Patents by Inventor Matthew R. Scholz

Matthew R. Scholz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIMIDINES FOR DEGRADING BRUTON'S TYROSINE KINASE
    Publication number: 20240109877
    Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4A, R4b, and R5, are as defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL.
    Type: Application
    Filed: March 21, 2023
    Publication date: April 4, 2024
    Inventors: Zhiguo Bian, Jason P. Burke, Zhaozhong J. Jia, Xingyu Jiang, Matthew H. Katcher, Venkat Reddy Mali, Violeta L. Marin, Elizabeth L. Noey, Akinori Okano, Alexey A. Rivkin, Spencer O. Scholz, Kevin R. Woller, Xianrui Zhao, Ashley M. Adams, Berenger Biannic, Shahab Mortezaei, Joshua N. Payette, Jeffery A. Zablocki
  • EXPRESSION CONSTRUCTS AND SYSTEMS FOR SYSTEMIC AND NON-SPECIFIC IN VIVO DELIVERY OF A NUCLEIC ACID TO HUMAN CELLS AND TRANSIENT TARGET CELL-SPECIFIC PRODUCTION OF A THERAPEUTIC PROTEIN
    Publication number: 20200009268
    Abstract: Provided are nucleic acid-based expression constructs for the targeted production of a therapeutic protein within a cell that is associated with aging, disease, another condition. Also provided are vectors and systems for the delivery of those nucleic acid-based expression constructs as well as methods for using such nucleic acid-based expression constructs, vectors, and systems for reducing, preventing, and/or eliminating the growth and/or survival of an age-, disease-, or condition-associated cell and for the treatment of a disease or condition that is associated with an age, disease, or condition associated cell.
    Type: Application
    Filed: September 25, 2019
    Publication date: January 9, 2020
    Applicant: Oisin Biotechnologies, Inc.
    Inventor: Matthew R Scholz
  • FUSOGENIC LIPID NANOPARTICLES AND METHODS FOR THE MANUFACTURE AND USE THEREOF FOR THE TARGET CELL-SPECIFIC PRODUCTION OF A THERAPEUTIC PROTEIN AND FOR THE TREATMENT OF A DISEASE, CONDITION, OR DISORDER ASSOCIATED WITH A TARGET CELL
    Publication number: 20190330657
    Abstract: Provided nucleic acid-based expression construct for the target cell-specific production of a therapeutic protein, such as a pro-apoptotic protein, within a target cell, including a target cell that is associated with aging, disease, or other condition, in particular a target cell that is a senescent cell or a cancer cell.
    Type: Application
    Filed: January 9, 2018
    Publication date: October 31, 2019
    Applicant: Oisin Biotechnologies, Inc.
    Inventor: Matthew R Scholz
  • SYSTEMS AND METHODS FOR THE TARGETED PRODUCTION OF A THERAPEUTIC PROTEIN WITHIN A TARGET CELL
    Publication number: 20160051700
    Abstract: Provided are nucleic acid-based expression constructs for the targeted production of a therapeutic protein within a cell that is associated with aging, disease, another condition. Also provided are vectors and systems for the delivery of those nucleic acid-based expression constructs as well as methods for using such nucleic acid-based expression constructs, vectors, and systems for reducing, preventing, and/or eliminating the growth and/or survival of an age-, disease-, or condition-associated cell and for the treatment of a disease or condition that is associated with an age, disease, or condition associated cell.
    Type: Application
    Filed: March 24, 2014
    Publication date: February 25, 2016
    Applicant: OISIN BIOTECHNOLOGIES
    Inventor: Matthew R Scholz
  • SYSTEMS AND METHODS FOR THE TARGETED PRODUCTION OF A THERAPEUTIC PROTEIN WITHIN A TARGET CELL
    Publication number: 20160010110
    Abstract: Provided are nucleic acid-based expression constructs for the targeted production of a therapeutic protein within a cell that is associated with aging, disease, another condition. Also provided are vectors and systems for the delivery of those nucleic acid-based expression constructs as well as methods for using such nucleic acid-based expression constructs, vectors, and systems for reducing, preventing, and/or eliminating the growth and/or survival of an age-, disease-, or condition-associated cell and for the treatment of a disease or condition that is associated with an age, disease, or condition associated cell.
    Type: Application
    Filed: September 23, 2015
    Publication date: January 14, 2016
    Applicant: OISIN BIOTECHNOLOGIES
    Inventor: Matthew R. Scholz