Patents by Inventor Matthew R. Volpe

Matthew R. Volpe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS RELATING TO CLBP INHIBITION
    Publication number: 20230190775
    Abstract: The technology described herein is directed to methods and compositions for inhibition of ClbP and the treatment and/or prevention of cancer, e.g., colorectal cancer, a urinary tract cancer, a squamous cell carcinoma, an oral squamous cell carcinoma, or a head-and-neck cancer.
    Type: Application
    Filed: February 10, 2023
    Publication date: June 22, 2023
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Matthew R. VOLPE, Emily BALSKUS
  • Methods and compositions relating to ClbP inhibition
    Patent number: 11617759
    Abstract: The technology described herein is directed to methods and compositions for inhibition of ClbP and the treatment and/or prevention of cancer, e.g., colorectal cancer, a urinary tract cancer, a squamous cell carcinoma, an oral squamous cell carcinoma, or a head-and-neck cancer.
    Type: Grant
    Filed: January 10, 2022
    Date of Patent: April 4, 2023
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Matthew R. Volpe, Emily Balskus
  • METHODS AND COMPOSITIONS RELATING TO CLBP INHIBITION
    Publication number: 20220387459
    Abstract: The technology described herein is directed to methods and compositions for inhibition of ClbP and the treatment and/or prevention of cancer, e.g., colorectal cancer, a urinary tract cancer, a squamous cell carcinoma, an oral squamous cell carcinoma, or a head-and-neck cancer.
    Type: Application
    Filed: January 10, 2022
    Publication date: December 8, 2022
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Matthew R. VOLPE, Emily BALSKUS
  • METHODS AND COMPOSITIONS RELATING TO GENOTOXIN COLIBACTIN
    Publication number: 20220033372
    Abstract: The technology described herein is directed to compounds which are substrates for ClbP, acting as fluorescent probes for ClbP activity. Further provided herein are methods for measuring ClbP activity, screening for ClbP inhibitors, detecting colibactin, and/or diagnosing cancer, which utilize the substrate compounds.
    Type: Application
    Filed: May 20, 2021
    Publication date: February 3, 2022
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Matthew R. Volpe, Emily Patricia Balskus, Matthew Ryan Wilson
  • Methods and compositions relating to genotoxin colibactin
    Patent number: 11040951
    Abstract: The technology described herein is directed to compounds which are substrates for ClbP, acting as fluorescent probes for ClbP activity. Further provided herein are methods for measuring ClbP activity, screening for ClbP inhibitors, detecting colibactin, and/or diagnosing cancer, which utilize the substrate compounds.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: June 22, 2021
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Matthew R. Volpe, Emily Patricia Balskus, Matthew Ryan Wilson
  • METHODS AND COMPOSITIONS RELATING TO GENOTOXIN COLIBACTIN
    Publication number: 20200055836
    Abstract: The technology described herein is directed to compounds which are substrates for ClbP, acting as fluorescent probes for ClbP activity. Further provided herein are methods for measuring ClbP activity, screening for ClbP inhibitors, detecting colibactin, and/or diagnosing cancer, which utilize the substrate compounds.
    Type: Application
    Filed: August 16, 2019
    Publication date: February 20, 2020
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Matthew R. Volpe, Emily Patricia Balskus, Matthew Ryan Wilson