Patents by Inventor Matthew Robert Johnson

Matthew Robert Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES
    Publication number: 20120083495
    Abstract: Compounds useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift.
    Type: Application
    Filed: December 5, 2011
    Publication date: April 5, 2012
    Applicants: SCIENCE APPLICATIONS INTERNATIONAL INC. (SAIC), ALBANY MOLECULAR RESEARCH, INC., DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Jill Heemskerk, Keith D. Barnes, John M. McCall, Graham Johnson, David Fairfax, Matthew Robert Johnson
  • Compounds for the treatment of spinal muscular atrophy and other uses
    Patent number: 8110681
    Abstract: Compounds of Formula (I) or (II) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: February 7, 2012
    Assignees: The United States of America as represented by the Secretary, Department of Health and Human Services, Albany Molecular Research, Inc., Science Applications International Inc. (SAIC)
    Inventors: Jill Heemskerk, Keith D. Barnes, John M. McCall, Graham Johnson, David Fairfax, Matthew Robert Johnson
  • Imidazole Amines As Inhibitors Of Beta-secretase
    Publication number: 20100168091
    Abstract: The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated 3-amyloid deposits or 3-amyloid levels in a patient.
    Type: Application
    Filed: March 5, 2010
    Publication date: July 1, 2010
    Applicant: Wyeth LLC
    Inventors: Michael Sotirios Malamas, Keith Douglas Barnes, Matthew Robert Johnson
  • Imidazole amines as inhibitors of ?-secretase
    Patent number: 7700606
    Abstract: The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated ?-amyloid deposits or ?-amyloid levels in a patient.
    Type: Grant
    Filed: August 16, 2007
    Date of Patent: April 20, 2010
    Assignee: Wyeth LLC
    Inventors: Michael Sotirios Malamas, Keith Douglas Barnes, Matthew Robert Johnson
  • COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES
    Publication number: 20090312323
    Abstract: Compounds of Formula (I) or (II) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift.
    Type: Application
    Filed: March 16, 2007
    Publication date: December 17, 2009
    Applicants: The Government of the United States of America, as represented by the Secretary, Department of HHS, Albany Molecular Research, Inc., Science Applications International Corporation
    Inventors: Jill Heemskerk, Keith D. Barnes, John M. McCall, Graham Johnson, David Fairfax, Matthew Robert Johnson
  • DIPHENYLIMIDAZOLYL COMPOUNDS AS INHIBITORS OF beta-SECRETASE
    Publication number: 20090042912
    Abstract: The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated ?-amyloid deposits or ?-amyloid levels in a patient.
    Type: Application
    Filed: October 7, 2008
    Publication date: February 12, 2009
    Applicant: Wyeth
    Inventors: Michael S. Malamas, James J. Erdei, Iwan S. Gunawan, Keith Douglas Barnes, Matthew Robert Johnson, Yu Hui
  • Diphenylimidazopyrimidines as inhibitors of ?-secretase
    Patent number: 7456186
    Abstract: The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated ?-amyloid deposits or ?-amyloid levels in a patient.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: November 25, 2008
    Assignee: Wyeth
    Inventors: Michael S. Malamas, James J. Erdei, Iwan S. Gunawan, Keith Douglas Barnes, Matthew Robert Johnson, Yu Hui