Abstract: The present invention relates to a compound of the Formula: and pharmaceutically salts thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: Ultraviolet light disinfection systems expose medical devices, surfaces, patients and healthcare clinicians to UV light having wavelengths consist with killing microorganisms. UV light systems may use logic to govern the operation of UV light sources so as to apply a disinfecting dose of the UV light. UV detectors measure UV light exposure. Enclosures contain medical devices and flood the medical devices with the UV light. Some enclosures accommodate a person. Some UV systems project UV light onto high-touch surfaces of a healthcare environment. Some systems may be deployed within a patient transport vehicle. Some UV systems may be incorporated into medical devices.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: A medical device comprising an enclosure defining a cavity for containing agent, a lumen for receiving a pressurized gas, and a barrier positioned between the cavity and the lumen, the barrier including at least one opening for storing agent, wherein rotation of the barrier relative to the lumen establishes fluid communication between the at least one opening and the lumen for delivering agent from the at least one opening to the lumen.

Abstract: A glass ceramic article including a lithium disilicate crystalline phase, a petalite crystalline phased, and a residual glass phase. The glass ceramic article has a warp (?m)<(3.65×10?9/?m×diagonal2) where diagonal is a diagonal measurement of the glass ceramic article in ?m, a stress of less than 30 nm of retardation per mm of glass ceramic article thickness, a haze (%)<0.0994t+0.12 where t is the thickness of the glass ceramic article in mm, and an optical transmission (%)>0.91×10(2-0.03t) of electromagnetic radiation wavelengths from 450 nm to 800 nm, where t is the thickness of the glass ceramic article in mm.

Abstract: Methods, systems, and techniques for facilitating publication of a media file at a scheduled time. A media aggregation client sends media and a scheduling request to a media scheduling system. The media scheduling system determines when it is time to publish the media and, when the time is appropriate, sends a notification to a media publishing client. In response to the notification, the media publishing client downloads the media to a scheduled publishing application, transfers the media and the metadata to a social network application, and the social network application publishes the media to a social network.

Abstract: Methods, systems, and techniques for facilitating publication of a media file at a scheduled time. A media aggregation client sends media and a scheduling request to a media scheduling system. The media scheduling system determines when it is time to publish the media and, when the time is appropriate, sends a notification to a media publishing client. In response to the notification, the media publishing client downloads the media to a scheduled publishing application, transfers the media and the metadata to a social network application, and the social network application publishes the media to a social network.

Abstract: Methods, systems, and techniques for facilitating publication of a media file at a scheduled time. A media aggregation client sends media and a scheduling request to a media scheduling system. The media scheduling system determines when it is time to publish the media and, when the time is appropriate, sends a notification to a media publishing client. In response to the notification, the media publishing client downloads the media to a scheduled publishing application, transfers the media and the metadata to a social network application, and the social network application publishes the media to a social network.

Abstract: Systems and methods for simultaneously acquiring three-dimensional data from multiple different frequency bins with a magnetic resonance imaging (“MRI”) system, and without frequency-encoding gradients, are provided. A multiband radio frequency (“RF”) pulse is used to excite spins associated with multiple different resonance frequency offsets, and a fully phase-encoded acquisition is used to acquire data, which may be spectrally-resolved data, from magnetic resonance signals formed in response to the multiband RF pulse.

Abstract: Methods, systems, and techniques for facilitating publication of a media file at a scheduled time. A media aggregation client sends media and a scheduling request to a media scheduling system. The media scheduling system determines when it is time to publish the media and, when the time is appropriate, sends a notification to a media publishing client. In response to the notification, the media publishing client downloads the media to a scheduled publishing application, transfers the media and the metadata to a social network application, and the social network application publishes the media to a social network.

Abstract: Systems and methods for simultaneously acquiring three-dimensional data from multiple different frequency bins with a magnetic resonance imaging (“MRI”) system, and without frequency-encoding gradients, are provided. A multiband radio frequency (“RF”) pulse is used to excite spins associated with multiple different resonance frequency offsets, and a fully phase-encoded acquisition is used to acquire data, which may be spectrally-resolved data, from magnetic resonance signals formed in response to the multiband RF pulse.

Abstract: A shared vehicle system includes a central facility, at least one vehicle distribution port facility and a plurality or fleet of vehicles, each having a vehicle subsystem. In general, the central station and port facility and the vehicle subsystems communicate in a manner to allow a user to enter information at a port facility. That information is then communicated to the central facility, where the information is processed to select a vehicle from the fleet to allocate to the user at the port facility. Selection of a vehicle for allocation to a user may be based on selecting an available or soon to be available vehicle according to various algorithms that take into account the vehicles state of charge.