Abstract: A method of forming a semiconductor device includes etching a semiconductor layer to form a plurality of mesa stripes in the semiconductor layer. The plurality of mesa stripes extend in a first direction and include mesa sidewalls that extend in the first direction and mesa surfaces at opposite ends of the mesa stripes. An additional mesa region is formed at an end of at least one of the mesa stripes. The additional mesa region is electrically insulated from the at least one of the mesa stripes. A semiconductor device structure includes a plurality of mesa stripes that extend in a first direction and include mesa sidewalls that extend in the first direction and mesa end surfaces at opposite ends of the mesa stripes. An additional mesa region that is electrically insulated from the at least one of the mesa stripes is at an end of at least one of the mesa stripes.

Abstract: Systems and methods for generating customized annotations of a medical record are provided. The system receives a medical record and processes it using a predictive model to identify evidence of a finding. The system then determines whether to have a recall enhancement or validation of a specific finding. Recall enhancement is used to tune or develop the predictive model, while validation is used to rapidly validate the evidence. The source document is provided to the user and feedback is requested. When asking for validation, the system also highlights the evidence already identified and requests the user to indicate if the evidence is valid for a particular finding. If recall enhancement is utilized, the source document is provided and the user is asked to find evidence in the document for a particular finding. The user may then highlight the evidence that supports the finding. The user may also annotate the evidence using free form text.

Abstract: Provided herein are polypeptides that bind to the malodour-causing substance DMTS. Also provided are nucleic acid sequences that encode for the polypeptides. Further provided herein is a method for identifying a compound that binds, suppresses, blocks, inhibits, and/or modulates the activity of one or more olfactory receptor that is activated by the malodor-causing substance DMTS comprising a) contacting the receptor, or a chimera or fragment thereof with a compound and b) determining whether the compound has an effect on the activity of the receptor. Further provided is an expression vector comprising the nucleic acid encoding the polypeptides described as well as a non-human organism or a host cell modified to express a receptor that is activated by DMTS. Also provided is the use of the polypeptides for identifying malodor modulating compounds.

Abstract: Systems and methods for personalizing medicine utilizing the true state of the patient are provided. A number of medical records for a patient are subjected to predictive modeling for various conditions (known as patient ‘true state’). The patient personal information, previous care, and true state may be provided into a state machine in order to determine the resources needed for the patient. The medical resources may be any of laboratory services, diagnostics, therapies and medications. Using the true state information, and number of activities may be performed for the patient based upon the patient's needs. These activities include scheduling lab or diagnostic procedures in advance of an appointment, filling in documentation gaps, identifying items that require additional documentation using the true state, and tracking follow-up. It may also be beneficial to validate the true state.

Abstract: A headgear assembly for retaining a respiratory mask on a user's face includes arrangements or components that allow for variation in a size of the headgear assembly. In some configurations, the headgear assembly includes one or more hubs, each of which are configured to connect a top and rear strap together. The size of the headgear assembly can be determined by the size or configuration of the hub. In other configurations, the headgear assembly comprises one or more spacer elements within one or more straps of the headgear. The size of the headgear assembly can be determined by the size of the spacer element or a relative position between the strap and the spacer element.

Abstract: A contact lens comprising one or more microchannels for transport of liquid through the lens is provided. The contact lens can be made by contacting a curable composition with a microfiber that is insoluble in the curable composition; curing the curable composition to provide a polymeric lens body with the microfiber embedded therein; and contacting the polymeric lens body with a solvent to dissolve the microfiber.

Abstract: A computer-implemented method of object enhancement in endoscopy images includes capturing an image of an object within a surgical operative site via an imaging device, determining a size of the object based on the captured image of the object, displaying the captured image of the object, and displaying on the displayed captured image of the object a representation of the determined size of the object.

Abstract: The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to assays and methods for screening and identifying compositions and/or ingredients that intensify a subject's perception of target odorant compounds based on the use of particular olfactory receptors activated by the target odorant compound.

Abstract: A diffuser element for use over a vent opening of a breathing assistance apparatus. In some configurations, the diffuser element is formed by knitting or weaving one or more threads together into an interlocking pattern. In some configurations, the diffuser pad has a first surface and an opposing second surface and at least the first surface includes a surface texture. Arrangements for coupling the diffuser element to a structure that defines or carries the vent are also disclosed.

Abstract: An interface for positive pressure therapy includes a mask assembly, a headgear assembly and a connection port assembly. The mask assembly comprises a seal member that has an upper portion movably connected to an integrated lower portion, wherein the upper portion rolls during hinging movement of the upper portion relative to the lower portion. The headgear assembly allows connection to the mask assembly in a direction substantially normal to a direction of strap tension. The connection port assembly includes a swivel elbow with a valve member that controls flow through a port that opens toward the user.

Abstract: Patient interface components and/or associated head gear and adjustment systems improve sealing and/or patient comfort and/or ease of use. The interface comprising an inflating or ballooning seal. The headgear assembly can be connected to the interface with an elastic component and an inelastic component. The elastic component enabling a course fitting of the interface to the patient and the inelastic component enabling a final fitting of the interface to the patient.

Abstract: A patient interface, including a mask assembly and a headgear assembly, provides improved facial sealing and improved ease of use. The mask assembly includes an inflating or ballooning seal. The seal can be secured between two portions of a snap-fit exoskeleton. The headgear assembly connects to the mask assembly with flexible straps during course fitting and with more rigid straps following course fitting. The straps include holes that fit over a tapering post on the mask assembly.

Abstract: A headgear assembly for retaining a respiratory mask on a user's face includes arrangements or components that allow for variation in a size of the headgear assembly. In some configurations, the headgear assembly includes one or more hubs, each of which are configured to connect a top and rear strap together. The size of the headgear assembly can be determined by the size or configuration of the hub. In other configurations, the headgear assembly comprises one or more spacer elements within one or more straps of the headgear. The size of the headgear assembly can be determined by the size of the spacer element or a relative position between the strap and the spacer element.

Abstract: A headgear portion or assembly for use in combination with a breathing apparatus in some configurations is at least substantially inelastic and is three dimensional in shape. The headgear portion or assembly can comprise a plastic core and a textile casing. The headgear, or part thereof, may also have integrally moulded labels, connectors, adjustment mechanisms and/or grips.

Abstract: A swirler apparatus for a combustor, including: primary and secondary swirlers disposed axially adjacent to each other along a swirler centerline; the primary swirler including a plurality of primary swirl vanes arrayed around the swirler centerline, each primary swirl vane including opposed sides bounded between opposed forward and aft edges and opposed leading and trailing edges; wherein the forward edge is oriented at a first vane angle with respect to a radial direction; wherein the aft edge is oriented at a second vane angle with respect to the radial direction; wherein the second vane angle is different from the first vane angle; and the secondary swirler including a plurality of secondary swirl vanes arrayed around the swirler centerline.

Abstract: Provided herein are polypeptides that bind to the malodour-causing substance DMTS. Also provided are nucleic acid sequences that encode for the polypeptides. Further provided herein is a method for identifying a compound that binds, suppresses, blocks, inhibits, and/or modulates the activity of one or more olfactory receptor that is activated by the malodor-causing substance DMTS comprising a) contacting the receptor, or a chimera or fragment thereof with a compound and b) determining whether the compound has an effect on the activity of the receptor. Further provided is an expression vector comprising the nucleic acid encoding the polypeptides described as well as a non-human organism or a host cell modified to express a receptor that is activated by DMTS. Also provided is the use of the polypeptides for identifying malodor modulating compounds.

Abstract: The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to the use of volatile compositions to limit, decrease or eliminate the perception of malodor. Such compositions include at least one malodor antagonist optionally combined with perfuming ingredients. Such compositions, their use in combination with delivery systems and their applications in consumer products are also objects of the present disclosure.

Abstract: The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to the use of volatile compositions to limit, decrease or eliminate the perception of malodor. Such compositions include at least one malodor antagonist optionally combined with perfuming ingredients. Such compositions, their use in combination with delivery systems and their applications in consumer products are also objects of the present disclosure.