Patents by Inventor Matthew S. Macauley

Matthew S. Macauley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective Glycosidase Inhibitors, Methods of Making Inhibitors, and Uses Thereof
    Publication number: 20080287375
    Abstract: The invention comprises compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions containing the compounds or prodrugs of the compounds. The invention also comprises animal models and methods of making the animal models for studying diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc, and treatment of such diseases and disorders. The invention also comprises methods of treating such diseases and disorders. The invention also comprises methods of making the compounds, and methods of making selective glycosidase inhibitors.
    Type: Application
    Filed: March 1, 2006
    Publication date: November 20, 2008
    Applicant: SIMON FRASER UNIVERSITY
    Inventors: David J. Vocadlo, Garrett Whitworth, Matthew S. Macauley