Patents by Inventor Matthew S. Palombo

Matthew S. Palombo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyethylene glycol-based dendrons
    Patent number: 9457099
    Abstract: The instant invention relates to polyethylene glycol-based dendrons, otherwise known as PEGtide dendrons, compositions thereof and methods of use.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: October 4, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Patrick J. Sinko, Jieming Gao, Yashveer Singh, Xiaoping Zhang, Matthew S. Palombo, Stanley Stein
  • Synergistic combinations to reduce particle dose for targeted treatment of cancer and its metastases
    Patent number: 9125835
    Abstract: Non-Small Cell Lung Carcinomas (NSCLCs) are treated with Gel Micro-Particles (GMPs) that passively accumulate in the lungs and contain Nano-Particles (NPs) combining one or more therapeutic agents that are cytotoxic to the NSCLC with one or more NSCLC active targeting ligands, as well as one or more other optional agents that increase cellular uptake, enhance the pro-apoptotic effect of the chemotherapeutic agent(s), and the like. NPs targeting other cancer cells are also disclosed, as well as NP-containing GMPs that reduce the occurrence of tumor metastasis.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: September 8, 2015
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Patrick J. Sinko, Jieming Gao, Manjeet Deshmukh, Xiaoping Zhang, Matthew S. Palombo, Sherif Ibrahim
  • POLYETHYLENE GLYCOL-BASED DENDRONS
    Publication number: 20120183578
    Abstract: The instant invention relates to polyethylene glycol-based dendrons, otherwise known as PEGtide dendrons, compositions thereof and methods of use.
    Type: Application
    Filed: November 14, 2011
    Publication date: July 19, 2012
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Patrick J. Sinko, Jieming Gao, Yashveer Singh, Xiaoping Zhang, Matthew S. Palombo, Stanley Stein
  • SYNERGISTIC COMBINATIONS TO REDUCE PARTICLE DOSE FOR TARGETED TREATMENT OF CANCER AND ITS METASTASES
    Publication number: 20120183621
    Abstract: Non-Small Cell Lung Carcinomas (NSCLCs) are treated with Gel Micro-Particles (GMPs) that passively accumulate in the lungs and contain Nano-Particles (NPs) combining one or more therapeutic agents that are cytotoxic to the NSCLC with one or more NSCLC active targeting ligands, as well as one or more other optional agents that increase cellular uptake, enhance the pro-apoptotic effect of the chemotherapeutic agent(s), and the like. NPs targeting other cancer cells are also disclosed, as well as NP-containing GMPs that reduce the occurrence of tumor metastasis.
    Type: Application
    Filed: November 14, 2011
    Publication date: July 19, 2012
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Patrick J. Sinko, Jieming Gao, Manjeet Deshmukh, Xiaoping Zhang, Matthew S. Palombo, Sherif Ibrahim
  • NANOCARRIER COMPOSITIONS AND METHODS
    Publication number: 20120093723
    Abstract: This invention provides multimeric nanocarrier for in vivo delivery of a bioactive agent, comprising at least two peptide monomers reversibly or irreversibly linked with one or more of said bioactive agents, wherein said two or more of said peptide monomers are covalently linked by a biodegradable difunctional moiety, as well as methods of using this nanocarrier.
    Type: Application
    Filed: March 16, 2010
    Publication date: April 19, 2012
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Patrick J. Sinko, Stanley Stein, Simi Gunaseelan, Shahrair Pooyan, Matthew S. Palombo, Xiaoping Zhang