Abstract: The present invention relates to a compound having general formula I for use in the activation of AMPK. A composition comprising said compound for use in the activation of AMPK is also provided.

Abstract: The present disclosure generally relates to managing and using an electronic key. In some embodiments, the electronic key is utilized to cause a vehicle to unlock one or more doors of the vehicle when a computer system that includes the electronic key is positioned within a first threshold distance of the vehicle. In some embodiments, a user interface object associated with the electronic key is displayed in a first position of an accounts user interface when a computer system that includes the electronic key is positioned within a second threshold distance of the vehicle.

Abstract: A head-mounted display (HMD) apparatus comprises a head attachment unit comprising a first attachment member configured to attach the HMD to a user's head when the HMD is worn by the user and a first element having an adjustable weight distribution, and an adjustment unit configured to adjust a distribution of the weight of the HMD based on user profile information associated with the user, wherein the adjustment unit is configured to adjust the weight distribution of the first element of the HMD based on the user profile information by adjusting a configuration of one or more mobile components of the first element without adjusting a position or an orientation of the first element with respect to the HMD.

Abstract: An image rendering method includes: selecting at least a first trained machine learning model from among a plurality of machine learning models, the machine learning model having been trained to generate data contributing to a render of at least a part of an image, where the at least first trained machine learning model has an architecture based learning capability that is responsive to at least a first aspect of a virtual environment for which it is trained to generate the data, and using the at least first trained machine learning model to generate data contributing to a render of at least a part of an image.

Abstract: An image rendering method for rendering a pixel at a viewpoint includes, for a first element of a virtual scene, having a predetermined surface at a position within that scene; providing the position and a direction based on the viewpoint to a machine learning system previously trained to predict a factor that, when combined with a distribution function that characterises an interaction of light with the predetermined surface, generates a pixel value corresponding to the first element of the virtual scene as illuminated at the position, combining the predicted factor from the machine learning system with the distribution function to generate the pixel value corresponding to the illuminated first element of the virtual scene at the position, and incorporating the pixel value into a rendered image for display, where the machine learning system was previously trained with a training set based on images comprising multiple lighting conditions.

Abstract: A method and apparatus for rotating a test specimen and simultaneously applying a torque, bending moment, and an axial load without the applied forces interfering with each other.

Abstract: A method and apparatus for measuring gas leakage in a graduated cylinder where water is displaced by the gas in a graduated cylinder in combination with a balance scale, allowing for both a visual indication of the gas detected and a change in weight measurement on the scale, correlating to a certain volume of gas detected.

Abstract: The present disclosure generally relates to managing and using an electronic key. In some embodiments, the electronic key is utilized to cause a vehicle to unlock one or more doors of the vehicle when a computer system that includes the electronic key is positioned within a first threshold distance of the vehicle. In some embodiments, a user interface object associated with the electronic key is displayed in a first position of an accounts user interface when a computer system that includes the electronic key is positioned within a second threshold distance of the vehicle.

Abstract: A data processing apparatus includes input circuitry to receive viewpoint data indicative of respective viewpoints for a plurality of spectators of a virtual environment, detection circuitry to detect a portion of the virtual environment viewed by each of the respective viewpoints in dependence upon the viewpoint data, selection circuitry to select one or more regions of the virtual environment in dependence upon at least some of the detected portions, and output circuitry to output data indicative of one or more of the selected regions.

Abstract: A content modification system comprising a content receiving unit operable to receive content comprising a virtual environment and one or more active elements, an input receiving unit operable to receive inputs from one or more users, an element addition unit operable to generate one or more virtual elements within the virtual environment in response to the received inputs, the virtual elements being unable to be interacted with by the one or more active elements, and a content generation unit operable to generate modified content comprising the virtual environment, the one or more active elements, and the one or more generated virtual elements.

Abstract: A content generation system, the system comprising an input obtaining unit operable to obtain one or more samples of input text and/or audio relating to a first content, an input analysis unit operable to generate n-grams representing one or more elements of the obtained inputs, a representation generating unit operable to generate a visual representation of one or more of the generated n-grams, and a display generation unit operable to generate second content comprising one or more elements of the visual representation in association with the first content.

Abstract: The present invention relates to a compound having general formula I for use in the activation of AMPK. A composition comprising said compound for use in the activation of AMPK is also provided.

Abstract: Described herein are egg white protein formulations, dosage containers containing the egg white protein formulations, methods of making the egg white protein formulations and dosage containers, and methods of controlling the quality of the egg white protein formulations, materials for manufacturing the egg white protein formulation (such as dried egg white protein powder), and the dosage containers. Further described herein are oral immunotherapy methods for treating an egg allergy. The method includes orally administering to the patient doses of a pharmaceutical composition comprising egg white protein according to an oral immunotherapy schedule. Also described herein are methods of adjusting a dosage of the pharmaceutical composition during oral immunotherapy if the patient experiences an adverse event related to the administration of a dose or a concurrent factor associated with increased sensitivity to an allergen that is not related to the administration of the dose.

Abstract: The invention relates in general to a medicament comprising Metformin or a salt thereof; and a compound having the general formula (I) or a salt thereof. The invention further relates to a pharmaceutical composition comprising the medicament for use in the prevention or treatment of a metabolic disease or a cardiovascular disease.

Abstract: A system and method automatically associates an image and passage from a text. In the system and method, a user can choose or supply an image and the system and/or method will choose a limited selection of relevant word passages for the image from a relatively large volume of potential passages. The system and method utilize a computer system wherein a concept generator and a passage generator processes the content of the image so as to assign words to describe the content, then weight the descriptive words (tags) and assign passages based on the tags and weighting. The passages can be filtered so as to remove inappropriate passages.

Abstract: Liquid formulations of insulin that contain physically and chemically stable insulin but do not contain preservatives or stabilizers are provided. The formulations also lack surfactants. The formulations are useful for various modes of delivery including pulmonary delivery.

Abstract: Liquid formulations of insulin that contain physically and chemically stable insulin but do not contain preservatives or stabilizers are provided. The formulations also lack surfactants. The formulations are useful for various modes of delivery including pulmonary delivery.

Abstract: A head-mounted display (HMD) apparatus comprises a head attachment unit comprising a first attachment member configured to attach the HMD to a user's head when the HMD is worn by the user and a first element having an adjustable weight distribution, and an adjustment unit configured to adjust a distribution of the weight of the HMD based on user profile information associated with the user, wherein the adjustment unit is configured to adjust the weight distribution of the first element of the HMD based on the user profile information by adjusting a configuration of one or more mobile components of the first element without adjusting a position or an orientation of the first element with respect to the HMD.

Abstract: A system and method automatically associates an image and passage from a text. In the system and method, a user can choose or supply an image and the system and/or method will choose a limited selection of relevant word passages for the image from a relatively large volume of potential passages. The system and method utilize a computer system wherein a concept generator and a passage generator processes the content of the image so as to assign words to describe the content, then weight the descriptive words (tags) and assign passages based on the tags and weighting. The passages can be filtered so as to remove inappropriate passages.

Abstract: A dry powder insulin formulation for reconstitution including insulin, a buffering agent, and a salt. The dry powder insulin formulation includes between about 70 and 95% w/w of insulin, between about 5 and 30% w/w of the buffering agent, and less than about 1% w/w of the salt. The dry powder insulin formulation has less than about 5% water content.