Abstract: Described herein are variant, novel cannabinoid synthases, nucleic acids encoding same, and various uses thereof.

Abstract: Systems and methods are provided for performing operations on an augmented reality (AR) device using an external vision system. The system establishes, by the AR device, a communication with an external client device. The system overlays, by the AR device, a first AR object on a real-world environment being viewed using the AR device. The system receives interaction data from the external client device representing movement of a user determined by the external client device. The system, in response to receiving the interaction data from the external client device, modifies the first AR object by the AR device.

Abstract: Systems and methods are provided for performing voice communication operations. The system establishes, by a first augmented reality (AR) device, a voice communication session between a plurality of users. The system displays, by the first AR device of a first user of the plurality of users, an avatar representing a second user of the plurality of users. The system receives, by the first AR device of a first user of the plurality of users, input from the first user that selects a display position for the avatar representing the second user within a real-world environment of the first user. The system animates the avatar representing the second user based on movement information received from a second AR device of the second user.

Abstract: A modular two-piece bolt system for firearms with blowback actions provides a rear bolt piece which detachably couples to plural different front bolt pieces each of different mass. The front bolt pieces have a similar configuration and common coupling interface which forms an interlocked relationship with a complementary configured coupling interface on the rear bolt piece to prevent axial separation of the pieces when the action of the firearm is cycled. The system allows various front bolt pieces to be selected and used interchangeably with the rear bolt piece so that a front bolt piece of proper mass can be matched to the energy of ammunition to be fired. The front and rear bolt pieces when coupled define a continuous extended longitudinal passage which receives the rear breech end portion of the firearm barrel therethrough to reduce the projected length of the barrel.

Abstract: Various embodiments provide systems, methods, devices, and instructions for protected data use in a third-party software application, where use can be enabled while maintaining protection of the protected data from the third party software application. In particular, various embodiments provide a software application architecture that permits a data party that owns or maintains protected data to support a software development ecosystem where a third-party can develop a third-party software application that uses the protected data while denying the third-party access to the protected data.

Abstract: Techniques for user behavior anomaly detection. At least one low-variance characteristic is compared to an expected result for the corresponding low-variance characteristics to determine if the low-variance characteristic(s) is/are within a pre-selected range of the expected results. A security response action is taken in response to the low-variance characteristic not being within the first pre-selected range of the expected results. At least one high-variance characteristic is compared to an expected result for the corresponding high-variance characteristics to determine if the high-variance characteristic(s) is/are within a pre-selected range of the expected results. A security response action is taken in response to the high-variance characteristic not being within the first pre-selected range of the expected results. Access is provided if the low-variance and the high-variance characteristics are within the respective expected ranges.

Abstract: Described herein are variant, novel cannabinoid synthases, nucleic acids encoding same, and various uses thereof.

Abstract: The disclosure relates to the biosynthesis of cannabinoids and related prenylated phenolic compounds using recombinant enzymes. In particular, the disclosure provides recombinant prenyltransferase enzymes engineered to produce a greater amount of a desired product, or to have a greater ability to catalyze a reaction using a desired substrate, as compared to the wild type prenyltransferase. The disclosure also provides methods of preparing such recombinant enzymes; as well as methods of use thereof in improving the biosynthesis of cannabinoids and related prenylated phenolic compounds.

Abstract: Described herein are prenyltransferases including non-natural variants thereof having at least one amino acid substitution as compared to its corresponding natural or unmodified prenyltransferases and that are capable of at least two-fold greater rate of formation of cannabinoids such as cannabigerolic acid, cannabigerovarinic acid, cannabigerorcinic acid, and cannabigerol, as compared to a wild type control. Prenyltransferase variants also accept different hydrophobic substrates (e.g., “donor” molecules), compared to wild type controls, to create different minor and novel cannabinoids. Prenyltransferase variants also demonstrated regioselectivity to desired cannabinoid isomers such as CBGA (3-GOLA), 3-GDVA, 3-GOSA, and CBG (2-GOL). The prenyltransferase variants can be used to form prenylated aromatic compounds, and can be expressed in an engineered microbe having a pathway to such compounds, which include 3-GOLA, 3-GDVA, 3-GOSA, and CBG.

Abstract: Described herein are variant, novel cannabinoid synthases, nucleic acids encoding same, and various uses thereof. In one aspect, a variant cannabinoid synthase or an active fragment thereof is provided comprising a non-naturally occurring amino acid sequence relative to a wild-type cannabinoid synthase or an active fragment thereof which acts on a substrate to produce an altered amount of a cannabinoid relative to an amount of the cannabinoid produced by the wild-type cannabinoid synthase or active fragment thereof.

Abstract: Systems and methods herein describe generating a shared list of media elements. The system detects a selection of an application icon within a chat interface and generates an application interface. The application interface comprises a media library. The system initiates a first user time limit and detects a selection of a media element from the media library. The system adds the media element to a shared list of media elements. Upon expiration of the first user time limit, the system initiates a second user time limit and detects a selection of a second media element from the media library. The system adds the second media element to the shared list of media elements. Upon expiration of the second user time limit, the system stores the shared list of media elements.

Abstract: Techniques for user behavior anomaly detection. At least one low-variance characteristic is compared to an expected result for the corresponding low-variance characteristics to determine if the low-variance characteristic(s) is/are within a pre-selected range of the expected results. A security response action is taken in response to the low-variance characteristic not being within the first pre-selected range of the expected results. At least one high-variance characteristic is compared to an expected result for the corresponding high-variance characteristics to determine if the high-variance characteristic(s) is/are within a pre-selected range of the expected results. A security response action is taken in response to the high-variance characteristic not being within the first pre-selected range of the expected results. Access is provided if the low-variance and the high-variance characteristics are within the respective expected ranges.

Abstract: The disclosure relates to the biosynthesis of cannabinoids and related prenylated phenolic compounds using recombinant enzymes. In particular, the disclosure provides recombinant mutant ORF2 enzymes engineered to produce a greater amount of a desired product, or to have a greater ability to catalyze a reaction using a desired substrate, as compared to WT ORF2. The disclosure also provides methods of preparing such ORF2 mutant enzymes; as well as methods of use thereof in improving the biosynthesis of cannabinoids and related prenylated phenolic compounds.

Abstract: Described herein are variant, novel cannabinoid synthases, nucleic acids encoding same, and various uses thereof.

Abstract: Techniques for user behavior anomaly detection. At least one low-variance characteristic is compared to an expected result for the corresponding low-variance characteristics to determine if the low-variance characteristic(s) is/are within a pre-selected range of the expected results. A security response action is taken in response to the low-variance characteristic not being within the first pre-selected range of the expected results. At least one high-variance characteristic is compared to an expected result for the corresponding high-variance characteristics to determine if the high-variance characteristic(s) is/are within a pre-selected range of the expected results. A security response action is taken in response to the high-variance characteristic not being within the first pre-selected range of the expected results. Access is provided if the low-variance and the high-variance characteristics are within the respective expected ranges.

Abstract: The disclosure relates to the biosynthesis of cannabinoids and related prenylated phenolic compounds using recombinant enzymes. In particular, the disclosure provides recombinant mutant ORF2 enzymes engineered to produce a greater amount of a desired product, or to have a greater ability to catalyze a reaction using a desired substrate, as compared to WT ORF2. The disclosure also provides methods of preparing such ORF2 mutant enzymes; as well as methods of use thereof in improving the biosynthesis of cannabinoids and related prenylated phenolic compounds.

Abstract: The disclosure relates to the biosynthesis of cannabinoids and related prenylated phenolic compounds using recombinant enzymes. In particular, the disclosure provides recombinant mutant ORF2 enzymes engineered to produce a greater amount of a desired product, or to have a greater ability to catalyze a reaction using a desired substrate, as compared to WT ORF2. The disclosure also provides methods of preparing such ORF2 mutant enzymes; as well as methods of use thereof in improving the biosynthesis of cannabinoids and related prenylated phenolic compounds.

Abstract: Techniques for user behavior anomaly detection. At least one low-variance characteristic is compared to an expected result for the corresponding low-variance characteristics to determine if the low-variance characteristic(s) is/are within a pre-selected range of the expected results. A security response action is taken in response to the low-variance characteristic not being within the first pre-selected range of the expected results. At least one high-variance characteristic is compared to an expected result for the corresponding high-variance characteristics to determine if the high-variance characteristic(s) is/are within a pre-selected range of the expected results. A security response action is taken in response to the high-variance characteristic not being within the first pre-selected range of the expected results. Access is provided if the low-variance and the high-variance characteristics are within the respective expected ranges.

Abstract: Virtual workplace server software may be selected for and/or provided to an organization server based on various characteristics of the organization. One or more inputs may be received corresponding to organization characteristics, for example, organization type and size, along with other potential organization characteristics and additional relevant information. Based on the organization characteristics and/or other relevant information, virtual workplace software may be selected for an organization server. The selection of the virtual workplace software may be output and/or the corresponding software may be downloaded and installed to provide desktop virtualization at the organization server. After the virtual workplace software is installed at a desktop virtualization server, the software may be used to provide virtual desktops to authorized end users and management functionality to authorized administrators.

Abstract: According to embodiments of the invention, a computer system extends an invitation to a plurality of content generators to request authentic content relating to one or more selected topics. The computer system receives content generated in response to the invitation and publishes that content online. The computer system calculates an efficacy of the request by obtaining data regarding to the online content and user interactions with the content. The computer system is configured to obtain data corresponding to user interactions with the content on the website hosting the content as well as user interactions with the content on third party websites such as Facebook® or Twitter®. Using that data, the computer system calculates an efficacy of the request. The computer system may also generate one or more reports to convey the calculated efficacy of the request.