Abstract: Provided herein are anti-CCR8 antibodies or antigen binding fragment thereof, which bind to CCR8, wherein the CCR8 is a human CCR8 and the antibody does not bind human CCR4. The anti-CCR8 antibodies or antigen binding fragment of the disclosure are useful for the treatment of cancer diseases through the elimination of regulatory T cells. Also provided herein are methods of use for the anti-CCR8 antibodies or antigen binding fragment thereof.

Abstract: A refuse body adapter includes a sub-frame assembly, a sub-frame adapter, and a spacer. The sub-frame assembly is configured to be coupled to a cargo body. The sub-frame adapter is configured to be coupled to a chassis of a vehicle. The spacer is coupled to both the sub-frame assembly and the sub-frame adapter. The spacer is disposed in a gap formed between the sub-frame assembly and the sub-frame adapter. A thickness of the spacer may be adjusted to accommodate different gap sizes between the sub-frame assembly and the sub-frame adapter.

Abstract: A system can include a processor and a computer-readable storage device storing instructions which, when executed by the processor, cause the processor to perform operations. The operations can include receiving an identification of a local device having a control module that manages a reader component and a locking mechanism and transmitting an authorized list to the local device that identifies authorized users that can gain access to the local device via the locking mechanism through interacting with the reader component. The control module on the local device can manage multiple functions of the local device including management of the reader component and the locking mechanism.

Abstract: Provided herein are anti-EGFRvII antibodies and binding fragments thereof. The anti-EGFRvIII antibodies of the disclosure are useful for the treatment of cancers through, e.g., antibody-dependent cell cytotoxicity (ADCC). Also provided herein are methods of making and using the anti-EGFRvIII antibodies for the treatment of cancer, and polynucleotides that encode the same.

Abstract: A system can include a processor and a computer-readable storage device storing instructions which, when executed by the processor, cause the processor to perform operations. The operations can include receiving an identification of a local device having a control module that manages a reader component and a locking mechanism and transmitting an authorized list to the local device that identifies authorized users that can gain access to the local device via the locking mechanism through interacting with the reader component. The control module on the local device can manage multiple functions of the local device including management of the reader component and the locking mechanism.

Abstract: Methods, systems, and computer-readable media for single-packet authorization using proof of work are disclosed. An access control service receives, from a client, a single-packet authorization (SPA) request. The (SPA) request comprises output of a proof-of-work task, wherein completion of the proof-of-work task requires computational resources or memory resources of the client. The access control service performs verification of the output of the proof-of-work task using fewer computational or memory resources of the access control service than were used by the client. In response to determining that verification of the output of the proof-of-work task succeeds, the access control service performs authentication of the SPA request. In response to determining that authentication of the SPA request succeeds, the access control service allows access by the client device to a service.

Abstract: A method for controlling rheology of a unit dose liquid detergent composition includes providing a detergent composition containing less than 20% water, a detergent surfactant, and a rheology modification system comprising iminodisuccinic acid (IDS), ethanol, and polyethylene glycol having a molecular weight of 200 to 1,000 Daltons; and encapsulating the detergent composition in a pouch made of a water soluble film. The viscosity of a mixture of 2 parts of a low water detergent composition to 1 part water can be maintained below 1,000 cp at 1.08 reciprocal seconds where the detergent composition includes about 1% to about 10% by weight of a mixture of IDS, ethanol, and polyethylene glycol having a molecular weight of 200 to 1,000 Daltons.

Abstract: Techniques for deperimeterized access control are described. A method of deperimeterized access control may include receiving, by a controller of a deperimeterized access control service, a single packet authorization (SPA) request for a session ticket from an agent on a electronic device, wherein the agent sends the request for the session ticket in response to intercepting traffic destined for a service associated with the deperimeterized access control service and determining that the agent does not have a session ticket for the service, authorizing the SPA request, providing a session ticket to the agent based on the request, receiving, by a gateway of the deperimeterized access control service, a request to initiate a session with a service, the request including the session ticket, validating the session ticket, and providing session parameters to the agent to be used to initiate the session between the electronic device and the service.

Abstract: A surgical access system comprising a tissue dilation assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures.

Abstract: A surgical access system comprising a tissue dilation assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures.

Abstract: A method for controlling rheology of a unit dose liquid detergent composition includes providing a detergent composition containing less than 20% water, a detergent surfactant, and a rheology modification system comprising iminodisuccinic acid (IDS), ethanol, and polyethylene glycol having a molecular weight of 200 to 1,000 Daltons; and encapsulating the detergent composition in a pouch made of a water soluble film. The viscosity of a mixture of 2 parts of a low water detergent composition to 1 part water can be maintained below 1,000 cp at 1.08 reciprocal seconds where the detergent composition includes about 1% to about 10% by weight of a mixture of IDS, ethanol, and polyethylene glycol having a molecular weight of 200 to 1,000 Daltons.

Abstract: Techniques for deperimeterized access control are described. A method of deperimeterized access control may include receiving, by a controller of a deperimeterized access control service, a single packet authorization (SPA) request for a session ticket from an agent on a electronic device, wherein the agent sends the request for the session ticket in response to intercepting traffic destined for a service associated with the deperimeterized access control service and determining that the agent does not have a session ticket for the service, authorizing the SPA request, providing a session ticket to the agent based on the request, receiving, by a gateway of the deperimeterized access control service, a request to initiate a session with a service, the request including the session ticket, validating the session ticket, and providing session parameters to the agent to be used to initiate the session between the electronic device and the service.

Abstract: A system for secure sharing of documents via a content management repository is provided. The system includes a content management unit, a filtering unit, a graphical user interface, and a memory communicatively coupled to the content management unit. The content management unit is configured to receive content restriction rules for content stored in the content management repository. The content management unit is further configured to inject the content restriction rules into policy rules. The content management unit is configured to intercept an Application Programming Interface call for the content from a user. The filtering unit is configured to dynamically filter the content based on the content restriction rules. The graphical user interface is configured to render the filtered content to display the filtered content to the user.

Abstract: An example system can include a battery-powered trash compactor or storage device that performs operations including receiving identification information via an external entity from a reader component. The reader component is connected to a control module that manages sensor components or other functions of the battery-powered storage device. The control module also controls a locking mechanism and reader component. Based on the identification information, via the control module, the battery-powered storage device unlocks the locking mechanism.

Abstract: A system can include a processor and a computer-readable storage device storing instructions which, when executed by the processor, cause the processor to perform operations. The operations can include receiving an identification of a local device having a control module that manages a reader component and a locking mechanism and transmitting an authorized list to the local device that identifies authorized users that can gain access to the local device via the locking mechanism through interacting with the reader component. The control module on the local device can manage multiple functions of the local device including management of the reader component and the locking mechanism.

Abstract: A pair of devices includes a first device and a second device that communicate lock control signals. The first device can have both a reader component and a control module that controls both (1) a first operation of the first device (such as a sensor control) and (2) a first locking component of the first device for accessing a first door of the first device. A second device can be in communication with the first device. The second device can have a second locking component for the second device for accessing a second door of the second device. The second device in one aspect does not having a reader component or a control module that independently controls the second locking component.

Abstract: A surgical access system comprising a tissue dilation assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures.

Abstract: A surgical access system comprising a tissue dilation assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures.

Abstract: A surgical access system comprising a tissue dilation assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures.

Abstract: A surgical access system comprising a tissue dilation assembly and a tissue retraction assembly, both of which may be equipped with one or more electrodes for use in detecting the existence of (and optionally the distance and/or direction to) neural structures.