Abstract: A doped or undoped silicon carbide film can be deposited using a remote plasma chemical vapor deposition (CVD) technique. One or more silicon-containing precursors are provided to a reaction chamber. Radical species, such as hydrogen radical species, are provided in a substantially low energy state or ground state and interact with the one or more silicon-containing precursors to deposit the silicon carbide film. A co-reactant may be flowed with the one or more silicon-containing precursors, where the co-reactant is a carbon-containing precursor and each silicon-containing precursor is a silane-based precursor with at least a silicon atom having two or more hydrogen atoms bonded to the silicon atom.

Abstract: This disclosure relates to the once weekly dosing regimen of a dual GLP-1R and GCGR agonist, formulations, and methods of using the same for treatment of chronic weight management, obesity and/or blood glucose control, including but not limited to dual agonist peptide product of SEQ ID NO. 1.

Abstract: A computing system identifies broadcast video data for a game. The computing system generates tracking data for the game from the broadcast video data using computer vision techniques. The tracking data includes coordinates of players during the game. The computing system generates optical character recognition data for the game from the broadcast video data by applying one or more optical character recognition techniques to each frame of the plurality of frames to extract score and time information from a scoreboard displayed in each frame. The computing system detects a plurality of events that occurred in the game by applying one or more machine learning techniques to the tracking data. The computing system receives play-by-play data for the game. The computing system generates enriched tracking data. The generating includes merging the play-by-play data with one or more of the tracking data, the optical character recognition data, and the plurality of events.

Abstract: A frame apparatus for displaying a flat article and a combined frame apparatus and flat article. In one aspect, the frame apparatus includes a display frame defining a rabbet, a stack positioned in the rabbet, and a spacer apparatus. The rabbet is defined by a floor and a wall. The wall includes an engagement feature which may be a channel. The spacer apparatus is configured to be positioned in the rabbet and engagement features thereof extend into the channel in the wall of the rabbet to couple the spacer apparatus to the display frame. The spacer assembly may also be in contact with the stack to hold the stack in the rabbet.

Abstract: A finance score determination system for determining a finance score of a consumer. The system includes a raw score determination unit for receiving at least creditworthiness data, consumer related data, and target asset related data to form received data, and processing the received data to determine a raw creditworthiness score, a raw monetary score, and a raw capacity score. The system includes a weighting unit for applying a selected weighted value to the raw scores to form weighted scores and a finance score determination unit for determining the finance score by arithmetically combining the weighted scores.

Abstract: A frame assembly for supporting a flat article. In one aspect, the frame assembly may include a stack including a transparent window panel and a frame. The frame may include a floor structure for supporting the stack and an outer annular wall coupled to and surrounding the floor structure, the outer annular wall including a plurality of corners, an outer surface defining a periphery of the frame, an inner surface defining a display cavity, and a front edge that defines a display opening configured to allow the stack to pass therethrough into the display cavity. The outer annular wall may have a non-uniform thickness. The corner portions may have lower and upper portions, with the lower portions having a greater thickness than the lower portions.

Abstract: The present invention relates to an infant feeding assembly, in particular an assembly which is sterilisable by steam generated within a container to which the assembly is mounted. The assembly includes a securing member for mounting an infant feeding nipple to a mouth of a container, and a surface including a cover contacting portion for selectively mounting a cover to the assembly. The assembly further includes a fluid flow path configured such that, when the securing member mounts the infant feeding nipple to the container in use, the container is fluidly connected to the surface. A method of sterilising the infant feeding assembly is also disclosed.

Abstract: A frame apparatus, a kit of parts which includes multiple frames and a connector bracket for connecting the frames together, and a method of interconnecting a plurality of frames and hanging the same from a support surface. The frame apparatus may be a front-loading frame whereby display items are inserted into a display cavity of the frame through an opening in the front surface of the frame through which the display cavity is viewed. The frame may include an outer annular wall that defines the display cavity, an inner annular wall that is spaced apart from the outer annular wall, and a floor that extends between the inner and outer annular walls. The floor may comprise a plurality of apertures to allow for attachment of the frame to various accessories including hanging brackets, connector brackets, trays, and the like.

Abstract: The present disclosure provides engineered Class 1 Type I CRISPR-Cas (Cascade) systems that comprise multi-protein effector complexes, nucleoprotein complexes comprising Type I CRISPR-Cas subunit proteins and nucleic acid guides, polynucleotides encoding Type I CRISPR-Cas subunit proteins, and guide polynucleotides. Also, disclosed are methods for making and using the engineered Class 1 Type I CRISPR-Cas systems of the present invention.

Abstract: A nipple for attachment to an external component, for example a container. The nipple comprises a base portion for attachment to the external component. The nipple also comprises a breast portion extending from the base portion. The nipple also comprises an areola portion extending from the breast portion. The nipple also comprises a teat portion extending from the areola portion. The breast portion extends at a first angle relative to an axis of the base portion and the areola portion extends at a second angle relative to the axis of the base portion, wherein the first angle is greater than the second angle.

Abstract: A valve including a valve body. An actuation housing of the valve body surrounds an actuation cavity. The actuation housing includes a first port configured for entry of actuating air and a second port configured for exhausting the actuating air. A poppet is configured for movement within the valve body and includes a barrier located within the actuation cavity. The poppet being actuated to an open position using the actuating air entering in the first port. When the poppet is in the open position, the actuating air flowing between the first port and the second port cools the stem.

Abstract: An apparel system for applying topical treatments includes an article of apparel configured to cover and interface with a skin surface of a human body, the article of apparel including an oleophobic and moisture wicking layer. A method for applying a topical treatment is also disclosed.

Abstract: The present disclosure provides novel synthetic nucleic acids and recombinant adeno-associated virus (rAAV) comprising the same, as well as methods of their use in the treatment of muscular dystrophies associated with a dystrophin mutation. Also provided are pharmaceutical compositions comprising a novel synthetic nucleic acid or rAAV of the invention, and a pharmaceutically acceptable carrier or excipient. Pharmaceutical compositions comprising an rAAV of the invention may be useful in gene therapy for the treatment of dystrophin-associated muscular dystrophies, such as Duchenne muscular dystrophy (DVD). Becker muscular dystrophy (BMD), and X-linked cardiomyopathy.

Abstract: This application relates to recombinant adeno-associated virus (rAAV) packaging and/or producer cell lines which have been engineered to reduce expression and/or activity of one or more genes and/or proteins to increase rAAV titers. The methods of generating the engineered cell lines have also been described herein.

Abstract: A nipple or teat, particularly a nipple for attachment to a container. The nipple comprises a breast portion having a central region, and a latch portion extending from the breast portion, the latch portion comprising a teat portion and an areola portion. The latch portion is radially offset from the central region of the breast portion and includes an outer wall. The outer wall of the latch portion includes a first region having a first wall thickness and a second region having a second wall thickness, wherein the second wall thickness is less than the first wall thickness. A nipple assembly, feeding assembly and comforter assembly, each including the nipple or teat, are also disclosed.

Abstract: A total artificial heart system includes at least one artificial ventricle coupled to (or capable of being coupled to) a chamber or a vessel of a human heart, and at least one drive system coupled to the artificial ventricle, the drive system including at least one implanted electric motor. The drive system causes the artificial ventricle to contract and expand.

Abstract: This disclosure relates to the once weekly dosing regimen of a dual GLP-1R and GCGR agonist, formulations, and methods of using the same for treatment of chronic weight management, obesity and/or blood glucose control, including but not limited to dual agonist peptide product of SEQ ID NO. 1.