Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.

Abstract: A locking mechanism for a link assembly of a work vehicle hitch has a locking plate mounted to an upper portion of the link assembly. A collar is positioned over the sleeve and is configured to slide relative a portion of the sleeve. The collar meshes with the sleeve so as to prevent rotational movement of the upper portion of the sleeve relative the collar when the collar is adjacent the upper portion, but the sleeve can rotate relative the collar when the collar is adjacent a middle portion of the sleeve. The locking mechanism has a handle mounted on the collar that is pivotable between a locked position where the handle is generally parallel with the sleeve in which the collar is prevented from sliding relative the sleeve and a released position generally perpendicular to the sleeve in which the collar is able to slide relative the sleeve.

Abstract: Systems and methods for automatically servicing autonomous vehicles are provided. In one example embodiment, a computer implemented method includes obtaining data associated with one or more reference mechanisms located on an autonomous vehicle. The method includes identifying information associated with the autonomous vehicle based at least in part on the data associated with the one or more reference mechanisms located on the autonomous vehicle. The information associated with the autonomous vehicle includes an orientation of the autonomous vehicle. The method includes determining a vehicle maintenance plan for the autonomous vehicle based at least in part on the information associated with the autonomous vehicle. The method includes providing one or more control signals to implement the vehicle maintenance plan for the autonomous vehicle based at least in part on the orientation of the autonomous vehicle.

Abstract: Systems and methods for automatically servicing autonomous vehicles are provided. In one example embodiment, a computer implemented method includes obtaining data associated with one or more reference mechanisms located on an autonomous vehicle. The method includes identifying information associated with the autonomous vehicle based at least in part on the data associated with the one or more reference mechanisms located on the autonomous vehicle. The information associated with the autonomous vehicle includes an orientation of the autonomous vehicle. The method includes determining a vehicle maintenance plan for the autonomous vehicle based at least in part on the information associated with the autonomous vehicle. The method includes providing one or more control signals to implement the vehicle maintenance plan for the autonomous vehicle based at least in part on the orientation of the autonomous vehicle.

Abstract: Systems and methods for automatically calibrating autonomous vehicle sensors are provided. In one example embodiment, a computer implemented method includes obtaining data associated with one or more targets located onboard an autonomous vehicle. The data associated with the targets is acquired via one or more first sensors located onboard a first portion of the autonomous vehicle. The targets are located onboard a second portion of the autonomous vehicle. The method includes determining a movement associated with the second portion of the autonomous vehicle based at least in part on the data associated with the targets. The method includes determining a sensor correction action associated with one or more second sensors located onboard the second portion of the autonomous vehicle based at least in part on the movement. The method includes implementing the sensor correction action for the second sensors located onboard the second portion of the autonomous vehicle.

Abstract: Systems and methods for controlling an autonomous vehicle based on a passenger-initiated action are provided. In one example embodiment, a computer implemented method includes detecting, by one or more computing devices on-board an autonomous vehicle, a first status change of a vehicle door. The first status change is associated with a first user action associated with the vehicle door. The method includes detecting a second status change of the vehicle door. The second status change is associated with a second user action associated with the vehicle door. The method includes determining one or more vehicle actions based at least in part on at least one of the first status change or the second status change associated with the vehicle door. The method includes providing one or more control signals to one or more systems on-board the autonomous vehicle to implement the vehicle actions.

Abstract: Systems and methods for controlling an autonomous vehicle are provided. In one example embodiment, a computer-implemented method includes receiving data indicative of an operating mode of the vehicle, wherein the vehicle is configured to operate in a plurality of operating modes. The method includes determining one or more response characteristics of the vehicle based at least in part on the operating mode of the vehicle, each response characteristic indicating how the vehicle responds to a potential collision. The method includes controlling the vehicle based at least in part on the one or more response characteristics.

Abstract: A drawbar assembly for coupling a drawbar to a tongue of a towed implement includes a drawbar pin and a drawbar clevis having a bore configured to receive the drawbar pin. A locking plate is coupled to the drawbar clevis and movable between a pin-lock condition in which the locking plate is configured to obstruct at least a portion of the bore, and a pin-unlock condition. An ejector mechanism is configured to dislodge the drawbar pin from the bore. The ejector mechanism includes a handle utilized to operate the ejector mechanism and an ejector arm pivotably disposed in an ejector recess in the clevis. The ejector arm is movable from a home position in which the ejector arm does not interfere with the drawbar pin to an eject position in which the ejector arm forces the drawbar pin to be at least partially dislodged out of the bore.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula I-A: or a pharmaceutically acceptable salt, wherein the variables are as defined herein.

Abstract: Systems, methods, and vehicles for controlling access to a vehicle are provided. In one example embodiment, a method includes obtaining, by one or more computing devices on-board an autonomous vehicle, a first set of data indicative of a first matrix from one or more remote computing devices that are remote from the autonomous vehicle. The method includes obtaining a second set of data indicative of a second matrix via one or more image capture devices on-board the autonomous vehicle. The method includes determining whether the first matrix corresponds to the second matrix based at least in part on a comparison of the first matrix and the second matrix. The method includes providing one or more control command signals to one or more control systems of the autonomous vehicle to provide a user access to the autonomous vehicle when the first matrix corresponds to the second matrix.

Abstract: Systems and methods for addressing a vehicle condition are provided. In one example embodiment, a method includes receiving data indicative of a condition associated with an autonomous vehicle. The autonomous vehicle is associated with a service provider that provides a service to a plurality of users of the service. The method includes identifying at least a subset of the plurality of users of the service based, at least in part, on a respective location associated with each user of the subset of users and a location of the vehicle. The method includes determining a selected user from the subset of users to address the condition associated with the vehicle based at least in part on one or more parameters. The method includes providing, to the selected user, a communication. The communication including a request that the selected user address the condition associated with the vehicle.

Abstract: A drawbar assembly for coupling a drawbar to a tongue of a towed implement includes a drawbar pin and a drawbar clevis having a bore configured to receive the drawbar pin. A locking plate is coupled to the drawbar clevis and movable between a pin-lock condition in which the locking plate is configured to obstruct at least a portion of the bore, and a pin-unlock condition. An ejector mechanism is configured to dislodge the drawbar pin from the bore. The ejector mechanism includes a handle utilized to operate the ejector mechanism and an ejector arm pivotably disposed in an ejector recess in the clevis. The ejector arm is movable from a home position in which the ejector arm does not interfere with the drawbar pin to an eject position in which the ejector arm forces the drawbar pin to be at least partially dislodged out of the bore.

Abstract: A drawbar assembly for coupling a drawbar to a tongue of a towed implement includes a drawbar pin and a drawbar clevis having a bore configured to receive the drawbar pin. A locking plate is coupled to the drawbar clevis and movable between a pin-lock condition in which the locking plate is configured to obstruct at least a portion of the bore, and a pin-unlock condition. An ejector mechanism is configured to dislodge the drawbar pin from the bore. The ejector mechanism includes a handle utilized to operate the ejector mechanism and an ejector arm pivotably disposed in an ejector recess in the clevis. The ejector arm is movable from a home position in which the ejector arm does not interfere with the drawbar pin to an eject position in which the ejector arm forces the drawbar pin to be at least partially dislodged out of the bore.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula I-A: or a pharmaceutically acceptable salt, wherein the variables are as defined herein.

Abstract: A drawbar assembly for coupling a drawbar to a tongue of a towed implement includes a drawbar pin and a drawbar clevis having a bore configured to receive the drawbar pin. A locking plate is coupled to the drawbar clevis and movable between a pin-lock condition in which the locking plate is configured to obstruct at least a portion of the bore, and a pin-unlock condition. An ejector mechanism is configured to dislodge the drawbar pin from the bore. The ejector mechanism includes a handle utilized to operate the ejector mechanism and an ejector arm pivotably disposed in an ejector recess in the clevis. The ejector arm is movable from a home position in which the ejector arm does not interfere with the drawbar pin to an eject position in which the ejector arm forces the drawbar pin to be at least partially dislodged out of the bore.

Abstract: Systems and methods disclosed herein provide a geo-targeted online reservation system that ensures authenticity of customer devices requesting reservations by generating reservations only if threshold authentication conditions are satisfied. For example, a computing device registered with a server system receives inputs for requesting a reservation of a limited release product and for configuring the product. To authenticate the computing device, the server device transmits an electronic message to the computing device requesting the computing device to respond. A response to the message is one threshold authentication condition for generating the reservation. Upon determining that one or more threshold authentication conditions are satisfied, the server device generates a reservation for the product.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I: or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula I-A: or a pharmaceutically acceptable salt, wherein the variables are as defined herein.

Abstract: An apparatus for use in controlling first and second downhole tools includes a first cyclical indexing mechanism associated with a first downhole tool, and a second cyclical indexing mechanism associated with a second downhole tool, wherein the first indexing mechanism defines at least three sequential indexing positions within a cycle and the second indexing mechanism defines at least two sequential indexing positions within a cycle. The apparatus includes at least one actuator for actuating the first and second indexing mechanisms in response to a common stimulus to cause said first and second indexing mechanisms to advance between respective indexing positions so as to permit co-ordination of the operational states of the associated first and second downhole tools. The apparatus may be used for controlling first and second under reamers or for controlling an under reamer and a corresponding stabilizer.

Abstract: A drawbar pin-retention assembly for use with a drawbar mechanism has a swinging drawbar, a support housing, and a device configured to prevent the swinging of the drawbar, the device having at least one drawbar pin. The pin-retention assembly includes a hanger bracket having a body portion and a pair of overhanging arms and a retaining bracket mounted on the hanger bracket with hinge tabs and pivotable about a pivot axis to move between a pin-retaining position and a pin-removal position. When the retaining bracket is pivoted to its pin-retaining position, a strap is positioned over the drawbar pin. Outward movement of the pin causes it to contact a forward portion of the strap forward of the pivot axis causing the retaining bracket to contact the hanger bracket thereby preventing pivoting of the retaining bracket in a first direction. The retaining bracket pivots by gravity to the pin-retention position.

Abstract: The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.