Abstract: A technique includes providing at least one service blueprint to orchestrate application programming interfaces to manage the lifecycle of at least one cloud service.

Abstract: In one aspect, a method includes receiving, by a content-management system and from a content-presentation device, a request for supplemental content, such as a replacement advertisement. The content-management system may then determine a technical characteristic of the content-presentation device and select supplemental content based at least in part on at least the determined technical characteristic of the content-presentation device. The content-management system may then cause the selected supplemental content to be transmitted to the content-presentation device to facilitate the content-presentation device performing a content modification operation.

Abstract: In one aspect, a method includes receiving first content at a content-presentation device and presenting the first content, the first content comprising a first audio-content component. The content-presentation device may receive second content comprising a second audio-content component. The content-presentation device may determine a switch time at which to switch from presenting the first content to presenting the second content. During a first time interval prior to the switch time and ending at the switch time, the volume of the first audio-content component may be decreased to zero. At the switch time, the content-presentation device may switch from presenting the first content to presenting the second content. During a second time interval beginning at the switch time and ending at a second time after the switch time, the volume of the second audio-content component may be increased from zero to a non-zero volume level.

Abstract: Disclosed herein are compositions and methods for detecting RNA binding sites and RNA interacting partners involving the use of a modified capture oligonucleotide having a dual toehold design.

Abstract: A king pin coupler assembly of a fifth wheel coupling. A coupler plate has a king pin aperture therein. A king pin is positioned to extend axially through the king pin aperture of the coupler plate. The king pin has a first portion with a neck for engaging a fifth wheel of the fifth wheel coupling, the first portion extending to a first side of the coupler plate. The king pin has a second portion on a second side of the coupler plate and welded to the coupler plate. A shielding apparatus is secured to one or both of the king pin and the coupler plate. The shielding apparatus includes a cover sealed to the first side of the coupler plate. The cover extends over the first portion of the king pin to shield the first portion of the king pin during liquid immersion of the king pin coupler assembly.

Abstract: Methods and assays are provided for isolating factors including polypeptides, ribonucleic acids (RNAs) and polypeptide complexes that are associated with a target nucleic acid sequence. The target nucleic acid sequence may be comprised within chromatin. The methods are suitable for identification and characterisation of factors including non-coding RNAs (ncRNAs) that associate with specified genomic loci.

Abstract: This invention relates to methods and compositions for detecting a polymorphism in a target nucleic acid sequence using isothermal nucleic acid amplification. More specifically, the present invention relates to using recombinase polymerase amplification (RPA) or Nicking and Extension Amplification Reaction (NEAR) to detect single nucleotide polymorphisms in a target nucleic acid sequence.

Abstract: Ghrelin signal peptide fragment assays and kits useful in the diagnosis, prognosis, risk stratification, assessing, staging, monitoring, categorizing and determination of further diagnoses and treatment regimens in subjects with various disorders, diseases and conditions including, pneumonia, heart failure, or pneumonia and heart failure or suspected pneumonia, heart failure, or pneumonia and heart failure, and methods for monitoring treatment.

Abstract: The invention provides methods and compositions for generating mutations in new nucleic acid molecules through incorporation of a transformable nucleoside into the nucleic acid and subsequent transformation of the nucleoside through oxidative-nucleophilic-aromatic-substitution chemistry, referred to as TimeLapse chemistry. The invention further provides methods for detecting the mutations, referred to as TimeLapse-seq.

Abstract: Disclosed is a method and a system for allowing real-time communication between real estate communication between real estate consumers and real estate professionals.

Abstract: An object has at least one electrophoretic display. A filter overlay covers at least a part of the electrophoretic display. Control circuitry is operable to control the electrophoretic display such that the appearance of the object viewed through the filter overlay can be adjusted.

Abstract: Embodiments of golf club heads with variable face geometry and material properties are described herein. Various embodiments include a golf club head comprising a body configured to receive a faceplate from a set of faceplates. The body comprises a heel region, a toe region opposite the heel region, a sole, and a crown. The faceplate is from the set of faceplates and coupled to the body. The set of faceplates comprises a heel region, a toe region, a top portion, and a bottom portion, and further comprises at least one of a varying hardness profile or a varying thickness profile. Other examples and related methods are also disclosed herein.

Abstract: A technique includes providing at least one service blueprint to orchestrate application programming interfaces to manage the lifecycle of at least one cloud service.

Abstract: A technique includes providing at least one service blueprint to orchestrate application programming interfaces to manage the lifecycle of at least one cloud service.

Abstract: A server-based system includes a server that is a centralized Internet of things (IoT) aggregator, broker, and control system, with a concierge function. The system allows any number of IoT devices and user interface devices to be placed on a single network, where the system translates data received from the IoT devices and the user interface devices into a single data standard, having a standardized language for each of the IoT devices and the user interface devices. This allows all of these devices to communicate and react to one another in an open fashion, and any user is afforded an opportunity to react with various things, such as public objects, as the user moves about to different places around the world. Additionally, a user may add another user to a Guestlist for a place, thus giving that other user limited control over the IoT devices in that place.

Abstract: Examples of calculating a minimum pipe wall to determine a pipe wall failure probability are disclosed. In one example implementation according to aspects of the present disclosure, a first acoustical sensor is connected to a pipe a distance from a second acoustical sensor connected to the pipe. A computing system is communicatively coupleable to the first and second acoustical sensors. The computing system calculates an average maximum pit depth value of a plurality of pits in an outer surface of a pipe wall of the pipe from a known initial pipe wall thickness value and an average present pipe wall thickness value. The computing system also calculates a minimum present pipe wall thickness by applying a statistical technique to the calculated average maximum pit depth value. The computing system determines a pipe wall failure probability based at least in part on the minimum present pipe wall thickness value.

Abstract: A method of instantiating a topology-based service using a blueprint, includes, with a topology designer, modeling the blueprint as a topology, with a resource offering manager, associating a number of policies and a number of lifecycle management actions (LCMAs) with a number of nodes within the topology, and with a lifecycle management (LCM) engine, instantiating the topology based on the policies and LCMAs.

Abstract: A hosted system provides any Internet user with the ability to quickly set up and customize a video channel, preferably as a web page or site that can be reached from any Internet-accessible device having a browser. The solution includes tools for use by channel site creators to customize look, feel, and page design. A particular web page or site may be associated with a given subject. A page or site that has such an association is sometimes referred to as “subject-specific.” Once a subject-specific channel is created, a site administrator or individual visitors can search and choose to bring those search results into the channel architecture. The system also enables a multiplatform search, and search results may be automatically populated into the channel content. The system enables the characterization of the material returned, preferably according to a user-generated taxonomy.

Abstract: A system includes an application blueprint to characterize a given application to enable lifecycle management of the given application on a cloud. An infrastructure blueprint is provided to characterize cloud infrastructure resources on the cloud and enable lifecycle management of the cloud infrastructure resources. A binding manager binds the application blueprint and the infrastructure blueprint to generate an aggregate blueprint based on the application blueprint and the infrastructure blueprint, wherein the aggregate blueprint enables the given application to utilize an instance of provisioned cloud resources specified by the infrastructure blueprint for lifecycle management on the cloud.

Abstract: A technique includes providing a service blueprint associated with a multitenant service to manage the lifecycle of a set of at least one existing cloud service. The blueprint is associated with recipes to orchestrate application programming interfaces to manage the lifecycle.