Abstract: Disclosed are chimeric antigen receptors (CARs) comprising Centyrins (i.e. CARTyrins), transposons encoding CARs and CARTyrins of the disclosure, cells modified to express CARs and CARTyrins of the disclosure, as well as methods of making and methods of using same for adoptive cell therapy.

Abstract: The present invention relates to improved light bar cover for LED light bars. The presently disclosed light bar covers may cover the full circumference and length of a light bar and may include a multi-functional tool for easing the installation or removal. While installed, the light bar cover protects the light bar from various damages such as debris or the elements. The multi-function tool may be used to assist in the removal and installation of the cover when mounted in hard to access location. In various embodiments the multi-function tool may be used to deploy the cover, provide rigidity to the cover, and/or actuate a fastener for the cover.

Abstract: The present invention relates to improved light bar cover for LED light bars. The presently disclosed light bar covers may cover the full circumference and length of a light bar and may include a multi-functional tool for easing the installation or removal. While installed, the light bar cover protects the light bar from various damages such as debris or the elements. The multi-function tool may be used to assist in the removal and installation of the cover when mounted in hard to access location. In various embodiments the multi-function tool may be used to deploy the cover, provide rigidity to the cover, and/or actuate a fastener for the cover.

Abstract: This invention relates to use of the compound N-[(R)-2,3-dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide for treating abnormal cell growth in mammals. In particular, the invention provides dosage regimes for administration of N-[(R)-2,3-dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide to mammals suffering from cancer.

Abstract: The present invention relates to methods involving the selection of peptides from complex displayed libraries to induce or detect signal transduction pathway activation. In one embodiment, the present invention provides methods for the selection of peptides capable of binding a viable cell and subsequently triggering or detecting programmed cell death (e.g., apoptosis). The present invention also provides compositions comprising the selected peptides suitable for medicinal and research use.