Patents by Inventor Matthew Stephen WAKE

Matthew Stephen WAKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES
    Publication number: 20240294651
    Abstract: The invention relates to antibodies or antigen-binding fragments thereof which specifically bind to CXCR4. The invention also relates to said antibodies for use in therapy, for use in treating cancer, and for use in treating a solid tumor. The invention also relates to pharmaceutical compositions comprising said antibodies, nucleic acids that encode said antibodies, vectors comprising said nucleic acids, and host cells comprising said nucleic acids or vectors.
    Type: Application
    Filed: January 29, 2024
    Publication date: September 5, 2024
    Applicant: KYMAB LIMITED
    Inventors: Margot BILLAUD, Robert ROWLANDS, John Matthew MCCOURT, Matthew Stephen WAKE, Morgane Marie LECOINTRE, Matthew Joseph BARNES, Catherine Jane HUTCHINGS, Kirstie BENNETT, Lisa STOTT
  • TREATMENT OF PD-L1 NEGATIVE OR LOW EXPRESSING CANCER WITH ANTI-ICOS ANTIBODIES
    Publication number: 20240190964
    Abstract: This invention relates to compositions and methods for the treatment of cancer, in particular difficult-to-treat cancers. More specifically, the present invention relates to compositions and methods for the treatment of PD-L1 negative or PD-L1 low expressing cancers using a modulator of ICOS, such as an anti-ICOS antibody, either alone or in combination with other agents, such as an anti-PD-L1 antibody.
    Type: Application
    Filed: November 15, 2023
    Publication date: June 13, 2024
    Inventors: Anthea NEWTON, Cintia Cristina PALU, Sonia QUARATINO, Richard Charles Alfred SAINSON, Cecilia DEANTONIO, Matthew Stephen WAKE