Abstract: The present application relates to treatment of myeloproliferative neoplasms using the JAK1/JAK2 inhibitor, ruxolitinib, in combination with a BET protein inhibitor, 2,2,4-trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-1,4-benzoxazin-3(4H)-one, wherein the combination is unexpectedly synergistic.

Abstract: There is provided an ammunition belt link comprising, a sprung wire, said sprung wire arranged to form a first receiving portion suitable for retaining a first ammunition cartridge, a second receiving portion suitable for retaining a second ammunition cartridge, a spacer between said first receiving and second receiving portions; and an ammunition cartridge locator aide, said aide locates in an ejector groove of a received cartridge.

Abstract: According to the present invention, there is provided an ammunition belt link comprising, a sprung wire, said sprung wire arranged to form a first receiving portion suitable for retaining a first ammunition cartridge, a second receiving portion suitable for retaining a second ammunition cartridge, a spacer between said first receiving and second receiving portions, an ammunition cartridge locator aide, said locator aid locates in an ejector groove of a received cartridge and, the wire ammunition belt link further comprising a support surface suitable for retaining the first and/or second ammunition cartridge.

Abstract: A textile printing material set includes a fabric substrate and an aqueous ink composition. The aqueous ink composition includes an aqueous ink vehicle, pigment, and from 2 wt % to 15 wt % of acrylic core-shell latex particles having an acrylic core copolymer with a glass transition temperature from ?50° C. to 30° C. and an acrylic shell copolymer having a glass transition temperature from 50° C. to 130° C. The acrylic core copolymer and the acrylic shell copolymer of the acrylic core-shell latex particles in this example are present at an average weight ratio from 1:1 to 9:1.

Abstract: The present application relates to treatment of myeloproliferative neoplasms using the JAK1/JAK2 inhibitor, ruxolitinib, in combination with a BET protein inhibitor, 2,2,4-trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-1,4-benzoxazin-3(4H)-one, wherein the combination is unexpectedly synergistic.

Abstract: There is disclosed a tracer munition. There is provided a tracer munition for selective activation, the tracer munition comprising: an electronic tracer device, said tracer munition comprising at least one cavity capable of receiving said electronic tracer device wherein the electronic tracer device comprises an electrical power source and an electronic emitter, whereupon selective activation of the electronic tracer device, said electronic emitter emits radiation.

Abstract: There is disclosed a tracer munition. There is provided a tracer munition for selective activation, the tracer munition comprising: an electronic tracer device, said tracer munition comprising at least one cavity capable of receiving said electronic tracer device wherein the electronic tracer device comprises an electrical power source and an electronic emitter, whereupon selective activation of the electronic tracer device, said electronic emitter emits radiation.

Abstract: A cartridge casing comprising a casing tube formed substantially of metal with a closed end and an open end. The casing tube bounds at least part of a head cap entered into the open end of the tube. The head cap is fixed relative to the tube. An end wall defines the closed end opposite the head cap end of the cartridge. The end wall comprises a weakened region.

Abstract: A cartridge casing comprises a casing tube having a first end and a head cap. The first end of the casing tube abuts and is joined with the head cap such that an orifice in the first end of the casing tube is aligned with a passage in the head cap to define a flash passage. The head cap and casing tube are held together by a deformable member.

Abstract: A cartridge casing comprises a casing tube and a head cap. The casing tube bounds at least part of the head cap. The head cap is being fixed relative to the tube by a welding process.

Abstract: A cartridge casing comprising a casing tube formed substantially of metal with a closed end and an open end. The casing tube bounds at least part of a head cap entered into the open end of the tube. The head cap is fixed relative to the tube. An end wall defines the closed end opposite the head cap end of the cartridge. The end wall comprises a weakened region.

Abstract: The invention relates to a conductive connection assembly (5), a method for manufacturing the same and a kit for a body (23) comprising carbon fibre-reinforced material, e.g. for a vehicle comprising a carbon fibre-reinforced body (23), with an electrical structural network for conducting electric discharges. The conductive connection assembly (5) includes a conductive interconnection element (1) with a conductive braid material (B). Furthermore, a kit is provided, the kit including at least two conductive connection assemblies (5) that are provided with differently shaped interconnection elements (1). Finally, a method that comprises the step of reshaping longitudinal ends (3, 4) of a braid material (B) is provided according to the invention.

Abstract: A cartridge casing comprises a casing tube having a first end and a head cap. The first end of the casing tube abuts and is joined with the head cap such that an orifice in the first end of the casing tube is aligned with a passage in the head cap to define a flash passage. The head cap and casing tube are held together by a deformable member.

Abstract: A cartridge casing comprises a casing tube and a head cap. The casing tube bounds at least part of the head cap. The head cap is being fixed relative to the tube by a welding process.

Abstract: An pneumatic insulating device (20) is disclosed comprising: a load bearing body, top (24) and bottom parts connected to the load bearing body; and a coiled, insulating pneumatic line (14, 14?) connect to and passing though the top and bottom parts, characterised by both the top and the bottom parts have fixing means (21) for fixing the device between external fixtures.

Abstract: The invention relates to a conductive connection assembly (5), a method for manufacturing the same and a kit for a body (23) comprising carbon fibre-reinforced material, e.g. for a vehicle comprising a carbon fibre-reinforced body (23), with an electrical structural network for conducting electric discharges. In order to improve durability of the body (23) with the electrical structural network, the invention provides that the conductive connection assembly (5) comprises a conductive interconnection element (1) with a conductive braid material (B). Furthermore, in order to simplify installing the electrical structural network to the body (23), a kit is provided, the kit comprising at least two conductive connection assemblies (5) that are provided with differently shaped interconnection elements (1). Finally, a method that comprises the step of reshaping longitudinal ends (3, 4) of a braid material (B) is provided according to the invention.

Abstract: A connecting arrangement for connecting supply lines across a gap between railway vehicles is disclosed. The connecting arrangement electrically and pneumatically connects railway vehicles or pantographs of a train. The connecting arrangement may include at least one flexible electrical power line and at least one flexible fluid line. The at least one power line and the at least one fluid line may be preassembled to form an integral unitary structure.

Abstract: The invention relates to a connecting arrangement for connecting supply lines across a gap between railway vehicles, comprising at least one flexible electrical power line and at least one flexible fluid line. To provide an improved connecting arrangement for electrically and pneumatically connecting railway vehicles or pantographs of a train, which is easy to handle and provides an increased reliability, the at least one power line and the at least one fluid line are preassembled to form an integral unitary structure.

Abstract: An pneumatic insulating device (20) is disclosed comprising : a load bearing body, top (24) and bottom parts connected to the load bearing body; and a coiled, insulating pneumatic line (14, 14?) connect to and passing though the top and bottom parts, characterised by both the top and the bottom parts have fixing means (21) for fixing the device between external fixtures.