Patents by Inventor Matthew Traylor

Matthew Traylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND SYSTEMS FOR HIGH-THROUGHPUT BIOCHEMICAL SCREENS
    Publication number: 20250034551
    Abstract: Provided are high-throughput screens for biologically active modulators of a target enzyme that mimic or recreate natural processes of diversification and selection. In some embodiments, the platform comprises one or more expression systems including without limitation (i) a two-hybrid system that, when expressed in a cell, links survival of the cell to the modulation of a therapeutic target, and (ii) a metabolic system that enables the biosynthesis of structurally varied modulators of the therapeutic agent.
    Type: Application
    Filed: November 3, 2022
    Publication date: January 30, 2025
    Inventors: Nolan O'CONNOR, Andrew MARKLEY, Hannah EDSTROM, Jerome Michael FOX, Tommaso Antonio FODERARO, Ankur Kulshreshtha SARKAR, Matthew TRAYLOR, Levi Daniel KRAMER, Gregory DONOVAN
  • LIPOPROTEIN LIPASE FOR TREATMENT OF HYPERTRIGLYCERIDEMIC-RELATED CONDITIONS INCLUDING ACUTE PANCREATITIS
    Publication number: 20170202929
    Abstract: A lipoprotein lipase (LPL) protein for treating and/or preventing HTG and its associated diseases, including but not limited to acute pancreatitis (AP), and in particular, acute pancreatitis secondary to or exacerbated by hypertriglyceridemia, and hypertriglyceridemia and its associated diseases in general, including cardiovascular and metabolic diseases, endocrine disorders, and fat embolism syndrome.
    Type: Application
    Filed: January 20, 2017
    Publication date: July 20, 2017
    Inventors: Omar L. Francone, Lin Guey, Kevin Holmes, Bruce Tangarone, Matthew Traylor, Lenore von Krusenstiern, Tracy Dowie, Lieh Yoon Low, Bohong Zhang, Muthuraman Meiyappan, Angela Norton, Bettina Strack-Logue, Dianna Lundberg, Michael F. Concino
  • Lipoprotein lipase for treatment of hypertriglyceridemic-related conditions including acute pancreatitis
    Patent number: 9597376
    Abstract: A lipoprotein lipase (LPL) protein for treating and/or preventing HTG and its associated diseases, including but not limited to acute pancreatitis (AP), and in particular, acute pancreatitis secondary to or exacerbated by hypertriglyceridemia, and hypertriglyceridemia and its associated diseases in general, including cardiovascular and metabolic diseases, endocrine disorders, and fat embolism syndrome.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: March 21, 2017
    Assignee: Shire Human Genetic Therapies, Inc.
    Inventors: Omar L. Francone, Lin Guey, Kevin Holmes, Bruce Tangarone, Matthew Traylor, Lenore von Krusenstiern, Tracy Dowie, Lieh Yoon Low, Bohong Zhang, Muthuraman Meiyappan, Angela Norton, Bettina Strack-Logue, Dianna Lundberg, Michael F. Concino
  • LIPOPROTEIN LIPASE FOR TREATMENT OF HYPERTRIGLYCERIDEMIC-RELATED CONDITIONS INCLUDING ACUTE PANCREATITIS
    Publication number: 20160051637
    Abstract: A lipoprotein lipase (LPL) protein for treating and/or preventing HTG and its associated diseases, including but not limited to acute pancreatitis (AP), and in particular, acute pancreatitis secondary to or exacerbated by hypertriglyceridemia, and hypertriglyceridemia and its associated diseases in general, including cardiovascular and metabolic diseases, endocrine disorders, and fat embolism syndrome.
    Type: Application
    Filed: August 19, 2015
    Publication date: February 25, 2016
    Inventors: Omar L. Francone, Lin Guey, Kevin Holmes, Bruce Tangarone, Matthew Traylor, Lenore von Krusenstiern, Tracy Dowie, Lieh Yoon Low, Bohong Zhang, Muthuraman Meiyappan, Angela Norton, Bettina Strack-Logue, Dianna Lundberg, Michael F. Concino