Patents by Inventor Matthew Vander Heiden

Matthew Vander Heiden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and products related to glutaminase inhibitors
    Patent number: 10786471
    Abstract: The invention relates to methods and related compositions for enhancing cancer therapy and in particular glutaminase inhibitor therapy. The methods involve methods for identifying patients susceptible to glutaminase inhibitor therapy as well as sensitizing patients to glutaminase inhibitor therapy.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: September 29, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Alexander Muir, Matthew Vander Heiden, Laura Danai, Dan Yi Gui
  • METHODS AND PRODUCTS RELATED TO GLUTAMINASE INHIBITORS
    Publication number: 20180221321
    Abstract: The invention relates to methods and related compositions for enhancing cancer therapy and in particular glutaminase inhibitor therapy. The methods involve methods for identifying patients susceptible to glutaminase inhibitor therapy as well as sensitizing patients to glutaminase inhibitor therapy.
    Type: Application
    Filed: February 6, 2018
    Publication date: August 9, 2018
    Applicant: Massachusetts Institute of Technology
    Inventors: Alexander Muir, Matthew Vander Heiden, Laura Danai, Dan Yi Gui
  • METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF CELLULAR PROLIFERATIVE DISORDERS
    Publication number: 20130203618
    Abstract: The present invention features methods and compositions for the diagnosis, prognosis, treatment, and/or amelioration of cellular proliferative disorders utilizing enzymes of the serine biosynthetic pathway (e.g., phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase (PSAT), or phosphoserine phosphatase (PSPH)).
    Type: Application
    Filed: May 26, 2011
    Publication date: August 8, 2013
    Applicant: BETH ISRAEL DEACONESS MEDICAL CENTER INC
    Inventors: Lewis C. Cantley, Matthew Vander Heiden, Jason Locasale, Hadar Sharfi
  • INHIBITORS OF PYRUVATE KINASE AND METHODS OF TREATING DISEASE
    Publication number: 20100099726
    Abstract: The invention provides pharmaceutical compositions, kits, and methods of treating cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia using compounds that selectively inhibit pyruvate kinase M2 and an assay measuring chemical modulation of pyruvate kinase activity.
    Type: Application
    Filed: August 6, 2007
    Publication date: April 22, 2010
    Inventors: Lewis Cantley, Matthew Vander Heiden, Heather R. Christofk