Patents by Inventor Matthew W. Mitchell

Matthew W. Mitchell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers for depression and methods using the same
    Patent number: 8394354
    Abstract: The present invention provides various biomarkers of depression. The present invention also provides various methods of using the biomarkers, including methods for diagnosis of depression, methods of determining predisposition to depression, methods of monitoring progression/regression of depression, methods of assessing efficacy of compositions for treating depression, methods of screening compositions for activity in modulating biomarkers of depression, methods of treating depression, as well as other methods based on biomarkers of depression.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: March 12, 2013
    Assignees: Metabolon, Inc., Duke University
    Inventors: Lisa A. Paige, Matthew W. Mitchell, Anne Evans, Don Harvan, David Carl Steffens, K. Ranga R. Krishnan, Rima Kaddurah-Daouk
  • Biomarkers for Pre-Diabetes, Cardiovascular Diseases, and Other Metabolic-Syndrome Related Disorders and Methods Using the Same
    Publication number: 20120208215
    Abstract: Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy.
    Type: Application
    Filed: April 27, 2012
    Publication date: August 16, 2012
    Applicant: METABOLON, INC.
    Inventors: Yun Fu HU, Costel CHIRILA, Danny ALEXANDER, Michael MILBURN, Matthew W. MITCHELL, Walter GALL, Kay A. LAWTON
  • Method for determining insulin sensitivity with biomarkers
    Patent number: 8187830
    Abstract: Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: May 29, 2012
    Assignee: Metabolon, Inc.
    Inventors: Yun Fu Hu, Costel Chirila, Danny Alexander, Michael Milburn, Matthew W. Mitchell, Walter Gall, Kay A. Lawton
  • Biomarkers Related to Insulin Resistance and Methods using the Same
    Publication number: 20120122981
    Abstract: Biomarkers relating to glucose disposal rate, insulin resistance, and/or insulin resistance-related disorders are provided. Methods based on the same biomarkers are also provided.
    Type: Application
    Filed: March 31, 2010
    Publication date: May 17, 2012
    Inventors: Yun Fu Hu, Costel Chirila, Danny Alexander, Michael Milburn, Matthew W. Mitchell, Walter Gall, Kay A. Lawton
  • Biomarkers for Prostate Cancer and Methods Using the Same
    Publication number: 20100292331
    Abstract: Methods for identifying and evaluating suites of biochemical and/or gene entities useful as biomarkers for early prediction of prostate cancer, disease grading, target identification/validation, and monitoring of drug efficacy are provided. Also provided are suites of small molecule entities as biomarkers for prostate cancer.
    Type: Application
    Filed: September 18, 2007
    Publication date: November 18, 2010
    Applicant: METABALON, INC.
    Inventors: Matthew W. Mitchell, Alvin Berger, Kay A. Lawton
  • Biomarkers Related To Metabolic Age and Methods Using The Same
    Publication number: 20100279337
    Abstract: Biomarkers relating to metabolic age are provided, as well as methods for using such biomarkers as biomarkers for determining metabolic age. In addition, methods for modulating the metabolic age of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for metabolic age.
    Type: Application
    Filed: July 13, 2010
    Publication date: November 4, 2010
    Applicant: Metabolon, Inc.
    Inventors: John Ryals, Mike Milburn, Matthew W. Mitchell, Kay A. Lawton
  • Biomarkers related to metabolic age and methods using the same
    Patent number: 7781160
    Abstract: Biomarkers relating to metabolic age are provided, as well as methods for using such biomarkers as biomarkers for determining metabolic age. In addition, methods for modulating the metabolic age of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for metabolic age.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: August 24, 2010
    Assignee: Metabolon, Inc.
    Inventors: John Ryals, Mike Milburn, Matthew W. Mitchell, Kay A. Lawton
  • Biomarkers for Depression and Methods Using the Same
    Publication number: 20100197626
    Abstract: The present invention provides various biomarkers of depression. The present invention also provides various methods of using the biomarkers, including methods for diagnosis of depression, methods of determining predisposition to depression, methods of monitoring progression/regression of depression, methods of assessing efficacy of compositions for treating depression, methods of screening compositions for activity in modulating biomarkers of depression, methods of treating depression, as well as other methods based on biomarkers of depression.
    Type: Application
    Filed: May 8, 2007
    Publication date: August 5, 2010
    Inventors: Lisa A. Paige, Matthew W. Mitchell, Anne Evans, Don Harvan
  • BIOMARKERS FOR ALZHEIMER'S DISEASE AND METHODS USING THE SAME
    Publication number: 20090318369
    Abstract: The present invention provides various biomarkers of Alzheimer's Disease (AD). The present invention also provides various methods of using the biomarkers, including methods for diagnosis of AD, methods of determining predisposition to AD, methods of monitoring progression/regression of AD, methods of assessing efficacy of compositions for treating AD, methods of screening compositions for activity in modulating biomarkers of AD, methods of treating AD, as well as other methods based on biomarkers of AD.
    Type: Application
    Filed: August 15, 2008
    Publication date: December 24, 2009
    Inventors: Lisa A. Paige, Matthew W. Mitchell, Anne Evans, Don Harvan
  • Biomarkers for pre-diabetes, cardiovascular diseases, and other metabolic-syndrome related disorders and methods using the same
    Publication number: 20090155826
    Abstract: Biomarkers relating to insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy are provided, as well as methods for using such biomarkers as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy. In addition, methods for modulating the respective disorders or conditions of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for insulin resistance, pre-diabetes, type-2 diabetes, metabolic syndrome, atherosclerosis, and cardiomyopathy.
    Type: Application
    Filed: July 17, 2008
    Publication date: June 18, 2009
    Applicant: Metabolon, Inc.
    Inventors: Yun Fu Hu, Costel Chirila, Danny Alexander, Michael Milburn, Matthew W. Mitchell, Walter Gall, Kay A. Lawton
  • METABOLOMIC PROFILING OF PROSTATE CANCER
    Publication number: 20090075284
    Abstract: The present invention relates to cancer markers. In particular, the present invention provides metabolites that are differentially present in prostate cancer.
    Type: Application
    Filed: August 15, 2008
    Publication date: March 19, 2009
    Applicants: The Regents of the University of Michigan, Metabolon, Inc.
    Inventors: Arul M. Chinnaiyan, Arun Sreekumar, Matthew W. Mitchell, Kay A. Lawton, Alvin Berger
  • BIOMARKERS RELATED TO METABOLIC AGE AND METHODS USING THE SAME
    Publication number: 20080124752
    Abstract: Biomarkers relating to metabolic age are provided, as well as methods for using such biomarkers as biomarkers for determining metabolic age. In addition, methods for modulating the metabolic age of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for metabolic age.
    Type: Application
    Filed: October 12, 2007
    Publication date: May 29, 2008
    Applicant: Metabolon, Inc.
    Inventors: John RYALS, Mike Milburn, Matthew W. Mitchell, Kay A. Lawton