Abstract: A radio-controlled (RC) motorcycle is disclosed with a chassis, a rear wheel, and a steerable front wheel assembly. The motorcycle includes an attitude estimator that uses rotation and acceleration data from an IMU to estimate an inertial attitude of the motorcycle. A receiver is connected to a control processor and receives a steering input from an RC transmitter. The control processor determines a desired roll angle based at least in part on the steering input from the receiver; determines a reported roll angle from the attitude estimate; and controls a steering angle of the front wheel assembly to reduce the difference (or reduce error) between the desired roll angle and the reported roll angle.

Abstract: The present invention relates to hydantoin derivatives having RNase H, polymerase and/or HIV reverse transcriptase modulatory, and particularly, inhibitory activity. Included in the invention are the hydantoin derivatives, compositions containing the derivatives, methods of synthesis of the derivatives, screening methods to identify the derivatives, and methods of treatment using the hydantoin derivatives, including the treatment of HIV, AIDS and retrovirus-associated cancer.

Abstract: The present invention provides a method of detecting a nuclease-mediated cleavage of a target nucleic acid through hybridizing a target nucleic acid to a fluorescently labeled oligonucleotide probe complementary to the target nucleic acid and containing a flourophor at one terminus and a quenching group at the other terminus. When the probe is unhybridized to the target nucleic acid, the probe adopts a conformation that places the flourophor and quencher in such proximity that the quencher quenches the flourescent signal of the flourophor and formation of the probe-target hybrid causes sufficient separation of the flourophor and quencher to reduce quenching of the flourescent signal of the flourophor. Once hybrized, the method contacts the probe-target hybrid with an agent having nuclease activity in an amount sufficient to selectively cleave the target nucleic acid and thereby release the intact probe.