Patents by Inventor Matthew Ware
Matthew Ware has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11939566Abstract: A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.Type: GrantFiled: September 2, 2021Date of Patent: March 26, 2024Assignee: DEKA Products Limited PartnershipInventors: Christopher C. Langenfeld, David D. B. Cannan, Dirk A. van der Merwe, Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Richard J. Lanigan, Michael A. Baker, David Blumberg, Jr., Richard E. Gautney, Derek G. Kane, Dane Fawkes, Thomas J. Bollenbach, Michael C. Tilley, Stuart A. Jacobson, John F. Mannisto
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Publication number: 20220340952Abstract: Embodiments allow for rapid antimicrobial susceptibility testing (AST) at a low cost. Embodiments may use changes in the pixel intensity from reflected light to determine microorganism growth and antimicrobial resistance. Dilutions of an antimicrobial are added to a standard well plate or other array. A pathogen or other microorganism may be added to the dilutions in the well plate. The well plate may be incubated for a time period less than 3 hours. The well plate may then be imaged and the resulting image data may be analyzed. Wells where the microorganism is able to grow may appear darker than wells where the microorganism did not grow. Differences pixel intensity of the wells is used to determine the susceptibility or resistance of the microorganism to the antimicrobial. The image data may be used to determine the minimum inhibitory concentration (MIC), the lowest dilution concentration of antimicrobial that inhibits growth.Type: ApplicationFiled: September 28, 2020Publication date: October 27, 2022Applicant: Beth Israel Deaconess Medical Center, Inc.Inventors: James E. Kirby, Ramy Arnaout, Kenneth P. Smith, Matthew Ware
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Publication number: 20220333056Abstract: A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.Type: ApplicationFiled: April 8, 2022Publication date: October 20, 2022Inventors: Christopher C. Langenfeld, David D. B. Cannan, Dirk A. van der Merwe, Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Richard J. Lanigan, Michael A. Baker, David Blumberg, JR., Richard E. Andrews, Derek G. Kane, Dane Fawkes, Thomas J. Bollenbach, Michael C. Tilley, Stuart A. Jacobson, John F. Mannisto
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Patent number: 11299705Abstract: A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.Type: GrantFiled: November 7, 2017Date of Patent: April 12, 2022Assignee: DEKA Products Limited PartnershipInventors: Christopher C. Langenfeld, David D. B. Cannan, Dirk A. van der Merwe, Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Richard J. Lanigan, Michael A. Baker, David Blumberg, Jr., Richard E. Gautney, Derek G. Kane, Dane Fawkes, Thomas J. Bollenbach, Michael C. Tilley, Stuart A. Jacobson, John F. Mannisto
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Publication number: 20220041975Abstract: A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.Type: ApplicationFiled: September 2, 2021Publication date: February 10, 2022Inventors: Christopher C. Langenfeld, David D. B. Cannan, Dirk A. van der Merwe, Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Richard J. Lanigan, Michael A. Baker, David Blumberg, JR., Richard E. Gautney, Derek G. Kane, Dane Fawkes, Thomas J. Bollenbach, Michael C. Tilley, Stuart A. Jacobson, John F. Mannisto
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Publication number: 20210395671Abstract: A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.Type: ApplicationFiled: September 2, 2021Publication date: December 23, 2021Inventors: Christopher C. Langenfeld, David D. B. Cannan, Dirk A. van der Merwe, Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Richard J. Lanigan, Michael A. Baker, David Blumberg, JR., Richard E. Gautney, Derek G. Kane, Dane Fawkes, Thomas J. Bollenbach, Michael C. Tilley, Stuart A. Jacobson, John F. Mannisto
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Publication number: 20210395672Abstract: A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.Type: ApplicationFiled: September 2, 2021Publication date: December 23, 2021Inventors: Christopher C. Langenfeld, David D. B. Cannan, Dirk A. van der Merwe, Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Richard J. Lanigan, Michael A. Baker, David Blumberg, JR., Richard E. Gautney, Derek G. Kane, Dane Fawkes, Thomas J. Bollenbach, Michael C. Tilley, Stuart A. Jacobson, John F. Mannisto
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Publication number: 20210009936Abstract: A fluid pumping and bioreactor system including at least two cassettes, at least one storage reservoir, at least one bioreactor, at least one manifold including valve modules, and tubing to connect the cassettes to the storage reservoir and the bioreactor. The cassettes can include pumps, valves, and fluid conduits and can be communicatively connected to the at least one manifold. The bioreactor can include an adapter and fluid conduits extending through the adapter from the exterior of the bioreactor to the interior of the bioreactor. System and method for generating a tissue for transplant by decellularizing and recellularizing a supplied tissue.Type: ApplicationFiled: September 22, 2020Publication date: January 14, 2021Inventors: Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Dirk A. van der Merwe, Richard J. Lanigan, Michael A. Baker, David Blumberg, JR.
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Patent number: 10808218Abstract: A fluid pumping and bioreactor system including at least two cassettes, at least one storage reservoir, at least one bioreactor, at least one manifold including valve modules, and tubing to connect the cassettes to the storage reservoir and the bioreactor. The cassettes can include pumps, valves, and fluid conduits and can be communicatively connected to the at least one manifold. The bioreactor can include an adapter and fluid conduits extending through the adapter from the exterior of the bioreactor to the interior of the bioreactor. System and method for generating a tissue for transplant by decellularizing and recellularizing a supplied tissue.Type: GrantFiled: March 21, 2019Date of Patent: October 20, 2020Assignee: DEKA Products Limited PartnershipInventors: Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Dirk A. van der Merwe, Richard J. Lanigan, Michael A. Baker, David Blumberg, Jr.
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Publication number: 20190218501Abstract: A fluid pumping and bioreactor system including at least two cassettes, at least one storage reservoir, at least one bioreactor, at least one manifold including valve modules, and tubing to connect the cassettes to the storage reservoir and the bioreactor. The cassettes can include pumps, valves, and fluid conduits and can be communicatively connected to the at least one manifold. The bioreactor can include an adapter and fluid conduits extending through the adapter from the exterior of the bioreactor to the interior of the bioreactor. System and method for generating a tissue for transplant by decellularizing and recellularizing a supplied tissue.Type: ApplicationFiled: March 21, 2019Publication date: July 18, 2019Inventors: Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Dirk A. van der Merwe, Richard J. Lanigan, Michael A. Baker, David Blumberg, JR.
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Patent number: 10294450Abstract: A fluid pumping and bioreactor system including at least two cassettes, at least one storage reservoir, at least one bioreactor, at least one manifold including valve modules, and tubing to connect the cassettes to the storage reservoir and the bioreactor. The cassettes can include pumps, valves, and fluid conduits and can be communicatively connected to the at least one manifold. The bioreactor can include an adapter and fluid conduits extending through the adapter from the exterior of the bioreactor to the interior of the bioreactor. System and method for generating a tissue for transplant by decellularizing and recellularizing a supplied tissue.Type: GrantFiled: October 7, 2016Date of Patent: May 21, 2019Assignee: DEKA Products Limited PartnershipInventors: Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Dirk A. van der Merwe, Richard J. Lanigan, Michael A. Baker, David Blumberg, Jr.
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Publication number: 20180127705Abstract: A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.Type: ApplicationFiled: November 7, 2017Publication date: May 10, 2018Inventors: Christopher C. Langenfeld, David D. B. Cannan, Dirk A. van der Merwe, Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Richard J. Lanigan, Michael A. Baker, David Blumberg, Richard E. Gautney, Derek G. Kane, Dane Fawkes, Thomas J. Bollenbach, Michael C. Tilley, Stuart A. Jacobson, John F. Mannisto
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Publication number: 20170101618Abstract: A fluid pumping and bioreactor system including at least two cassettes, at least one storage reservoir, at least one bioreactor, at least one manifold including valve modules, and tubing to connect the cassettes to the storage reservoir and the bioreactor. The cassettes can include pumps, valves, and fluid conduits and can be communicatively connected to the at least one manifold. The bioreactor can include an adapter and fluid conduits extending through the adapter from the exterior of the bioreactor to the interior of the bioreactor. System and method for generating a tissue for transplant by decellularizing and recellularizing a supplied tissue.Type: ApplicationFiled: October 7, 2016Publication date: April 13, 2017Inventors: Dean Kamen, Jason A. Demers, Frederick Morgan, Timothy D. Moreau, Brian D. Tracey, Matthew Ware, Dirk A. van der Merwe, Richard J. Lanigan, Michael A. Baker, David Blumberg, JR.