Patents by Inventor Matthew Wecker

Matthew Wecker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systematic evolution of ligands by exponential enrichment: Chemi-SELEX
    Publication number: 20060088877
    Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
    Type: Application
    Filed: December 6, 2005
    Publication date: April 27, 2006
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Larry Gold, Bruce Eaton, Drew Smith, Matthew Wecker, Kirk Jensen
  • Systematic evolution of ligands by exponential enrichment: Chemi-ESLEX
    Publication number: 20030186231
    Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
    Type: Application
    Filed: October 9, 2001
    Publication date: October 2, 2003
    Inventors: Larry Gold, Bruce Eaton, Drew Smith, Matthew Wecker, Kirk Jensen
  • Systematic evolution of ligands by exponential enrichment: Chemi-SELEX
    Patent number: 6300074
    Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: October 9, 2001
    Assignee: Gilead Sciences, Inc.
    Inventors: Larry Gold, Bruce Eaton, Drew Smith, Matthew Wecker, Kirk Jensen
  • Systematic evolution of ligands by exponential enrichment: chemi-SELEX
    Patent number: 5998142
    Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
    Type: Grant
    Filed: August 21, 1997
    Date of Patent: December 7, 1999
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Larry Gold, Bruce Eaton, Drew Smith, Matthew Wecker, Kirk Jensen
  • Systematic evolution of ligands by exponential enrichment: chemi-selex
    Patent number: 5962219
    Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: October 5, 1999
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Larry Gold, Bruce Eaton, Drew Smith, Matthew Wecker, Kirk Jensen
  • Systematic evolution of ligands by exponential enrichment: Chemi-SELEX
    Patent number: 5763595
    Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 9, 1998
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Larry Gold, Bruce Eaton, Drew Smith, Matthew Wecker, Kirk Jensen
  • Systematic evolution of ligands by exponential enrichment: chemi-SELEX
    Patent number: 5705337
    Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
    Type: Grant
    Filed: March 8, 1995
    Date of Patent: January 6, 1998
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Larry Gold, Bruce Eaton, Drew Smith, Matthew Wecker, Kirk Jensen
  • High-affinity oligonucleotide ligands to the tachykinin substance P
    Patent number: 5648214
    Abstract: Methods are described for the identification and preparation of nucleic acid ligands to Substance P (SP). Included in the invention are specific RNA ligands to SP identified by the SELEX method.
    Type: Grant
    Filed: September 9, 1994
    Date of Patent: July 15, 1997
    Assignee: University Research Corporation
    Inventors: Dan T. Nieuwlandt, Larry Gold, Matthew Wecker
  • High-affinity oligonucleotide ligands to the tachykinin substance P
    Patent number: 5637682
    Abstract: Methods are described for the identification and preparation of nucleic acid ligands to Substance P (SP). Included in the invention are specific RNA ligands to SP identified by the SELEX method.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: June 10, 1997
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Dan T. Nieuwlandt, Larry Gold, Matthew Wecker
  • Microbiological production of acetaldeyde
    Patent number: 4900670
    Abstract: Acetaldehyde producing strains of Zymononas mobilis are produced by selection against allyl alcohol. The selected strain produces acetaldehyde in a carbohydrate containing medium under direct aeration.
    Type: Grant
    Filed: February 23, 1988
    Date of Patent: February 13, 1990
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Robert R. Zall, Matthew Wecker