Patents by Inventor Matthew Weinstock

Matthew Weinstock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KNOCKOUT OF ptsP GENE ELEVATES ACTIVE GENE EXPRESSION
    Publication number: 20250059259
    Abstract: Variant or mutant prokaryotic cells are disclosed that express elevated or increased levels of a wide variety of active proteins. Also disclosed are methods of producing the elevated or increased levels of active encoded proteins.
    Type: Application
    Filed: December 22, 2022
    Publication date: February 20, 2025
    Inventor: Matthew Weinstock
  • COMPOSITION OF TRANSFER RNAS AND USE IN PRODUCTION OF PROTEINS CONTAINING NON-STANDARD AMINO ACIDS
    Publication number: 20240263209
    Abstract: This disclosure provides engineered tRNAs and the corresponding aminoacyl tRNA synthetase for efficient production of proteins containing non-standard amino acids. These engineered orthogonal tRNA (O-tRNA)/orthogonal aminoacyl tRNA synthetase (O-RS) pair, i.e., Orthogonal Translation Systems (OTSs) can be used to incorporate a non-standard amino acid in a specific position in a growing polypeptide in response to a selector codon that is recognized by the engineered tRNA.
    Type: Application
    Filed: March 15, 2024
    Publication date: August 8, 2024
    Inventors: Yi Zhang, Matthew Weinstock, Miles Gander
  • POLYPEPTIDE CLEAVAGE METHODS
    Publication number: 20230159598
    Abstract: Methods and constructs for the cleavage of polypeptides at one or more specific positions within the polypeptide are provided.
    Type: Application
    Filed: April 20, 2021
    Publication date: May 25, 2023
    Inventors: Tyler Nusca, Johan Kers, Matthew Weinstock, Michelle Slind, Amy Doerner, Michael Cammarata, Abigail Ward