Abstract: A compound of formula I having the structure: or a pharmaceutically acceptable salt thereof, wherein A1 and A2 are independently O or S; X is selected from CH2, CD2, NR3, O, and S, where R3 is selected from hydrogen, C1-C4 linear or branched chain alkyl, halo(C1-C4)linear or branched chain alkyl, and hydroxyl(C1-C4)linear or branched chain alkyl; Y and Z are selected from C and N, where when Y is C, then Z is N, and when Y is N, then Z is C; R1 and R2 are independently selected from hydrogen, deuterium, C1-C4 linear or branched chain alkyl, etc.; or a C1-C2 alkyl substituted with a C3-C5 cycloalkyl ring; or taken together to form a C3-C6 cycloalkyl ring; or where X is CH2 or CD2, then R1 and R2 are independently selected from hydrogen, deuterium, halogen, hydroxyl, C1-C4 linear or branched chain alkyl, etc.; R4 is selected from hydrogen, deuterium, cyano, halogen, (C1-C3) alkoxy, etc.; R5 is selected from hydrogen, deuterium, halogen, C1-C3 alkoxy, amino, (C1-C4 linear or branched chain alkyl)amino, etc.

Abstract: Disclosed herein is a bracket connectable to a stator core of an electrical machine. The bracket includes a comb portion having a plurality of teeth arranged in at least one row such that an indentation is defined between each pair of adjacent teeth. Each indentation is sized to receive a portion of a busbar therein. The bracket further includes a tab sized and shaped to be received within a mounting recess defined in the stator core, and an arm extending between the comb portion and the tab such that the comb portion is offset from the tab.

Abstract: A processor-implemented method for simultaneously tracking one or more objects includes receiving, via a dynamical system with a set of sensors, a first set of unlabeled measurements from one or more objects. Each of the measurements is a function of time. A set of candidate tracks is determined for the one or more objects. Probabilities of each of the first set of unlabeled measurements being assigned to each of the set of candidate tracks are computed. A track from the set of candidate tracks is determined for each of the one or more objects based on a joint probability distribution of track attributes and the probabilistic assignment of each of the first set of unlabeled measurements to each of the set of candidate tracks.

Abstract: The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as no more than 12 weeks. In one aspect, the treatment comprises administering at least two direct acting antiviral agents to a subject with HCV infection, wherein the treatment lasts for 12 weeks and does not include administration of either interferon or ribavirin, and said at least two direct acting antiviral agents comprise (a) Compound 1 or a pharmaceutically acceptable salt thereof and (b) Compound 2 or a pharmaceutically acceptable salt thereof.

Abstract: A wheel servicing machine such as a wheel balancer includes an acoustic transducer configured to measure energy of one or more reflected acoustic waves after the waves have bounced off a material boundary surface such as a wheel assembly. In some embodiments, a return energy index signal representative of the measured energy is generated by a transducer and is further processed by a processor to control operations of the machine. The acoustic transducer also measures distance between the transducer and the wheel assembly surface in some embodiments. One or more values in a sample queue of acquired distance data may be flagged, or indexed, based on variation in the magnitude of the return energy signal. Methods of measuring wheel width using sonar measurement of both distance and reflected energy are also provided.

Abstract: An apparatus for a wheel service machine includes a body having an axis and a aperture through the axis, the aperture shaped to receive a rotary shaft, a first chamber and a second chamber located in the body, a pneumatic inlet communicated with the second chamber, the pneumatic inlet configured to be couple to a pneumatic supply line. A piston is movably disposed in the first chamber between a retracted and an extended position, the piston moving from the retracted position to the extended position when pressure from the second chamber is supplied to the first chamber. A valve is positioned between the first and second chambers, the valve selectively communicating the first and second chambers. A wheel service apparatus includes a base, a motor configured to rotate a rotary shaft, and a pneumatic nut. A docking station for the pneumatic nut can be located on the base.

Abstract: A wheel servicing machine such as a wheel balancer includes an acoustic transducer configured to measure energy of one or more reflected acoustic waves after the waves have bounced off a material boundary surface such as a wheel assembly. In some embodiments, a return energy index signal representative of the measured energy is generated by a transducer and is further processed by a processor to control operations of the machine. The acoustic transducer also measures distance between the transducer and the wheel assembly surface in some embodiments. One or more values in a sample queue of acquired distance data may be flagged, or indexed, based on variation in the magnitude of the return energy signal. Methods of measuring wheel width using sonar measurement of both distance and reflected energy are also provided.

Abstract: A method for a robotic semiconductor wafer processing system to correct for wafers that have become offset or off-center during wafer processing. This is accomplished by determining the amount of offset and re-centering the wafer during wafer transport to the next process station using a single station sensor to locate the wafer center point. Each single sensor located at each station activates when the wafer's edge traverses through the sensor's path. Directional coordinates for the measured designated points on the wafer's edge are calculated, and the intersection points of two circles, analytically derived from using the measured designated points as their centers, are determined. The intersection point closest to the true wafer center position represents the measured wafer's center point. This point is compared to the true wafer center position, and the wafer is then adjusted for this difference.