Abstract: A system and method for matching students to tutors is disclosed. In particular, a user submits a query and in response a plurality of tutors are identified responsive to the search query. The identified tutors are then ranked based on relevance to the search query. The identified tutors are then presented to the user in an order based on the relevance score assigned to each tutor.

Abstract: A system and method for matching students to tutors is disclosed. In particular, a user submits a query and in response a plurality of tutors are identified responsive to the search query. The identified tutors are then ranked based on relevance to the search query. The identified tutors are then presented to the user in an order based on the relevance score assigned to each tutor.

Abstract: A system and method for matching students to tutors is disclosed. In particular, a user submits a query and in response a plurality of tutors are identified responsive to the search query. The identified tutors are then ranked based on relevance to the search query. The identified tutors are then presented to the user in an order based on the relevance score assigned to each tutor.

Abstract: A system and method for matching students to tutors is disclosed. In particular, a user submits a query and in response a plurality of tutors are identified responsive to the search query. The identified tutors are then ranked based on relevance to the search query. The identified tutors are then presented to the user in an order based on the relevance score assigned to each tutor.

Abstract: Embodiments disclosed herein generally relate to an access sheath and access systems. In some embodiments, the access sheath may be non-adjustable access sheath or an adjustable access sheath. For example, a length of the adjustable access sheath may be modified or customized (e.g., before insertion thereof in a patient) to a suitable length for a particular patient. In some embodiments, the access sheath and/or dilator may have a substantially fixed or predetermined length.

Abstract: Embodiments disclosed herein generally relate to an access sheath and access systems. In some embodiments, the access sheath may be non-adjustable access sheath or an adjustable access sheath. For example, a length of the adjustable access sheath may be modified or customized (e.g., before insertion thereof in a patient) to a suitable length for a particular patient. In some embodiments, the access sheath and/or dilator may have a substantially fixed or predetermined length.

Abstract: The invention relates to a method of determining the amount of a target nucleic acid sequence in a sample, the method comprising: obtaining multiple distinguishable amplicons of the target nucleic acid sequence, each comprising a distinguishing tag and a target portion; amplifying the amplicons in a single reaction volume; and detecting nucleic acids amplified from the amplicons. Detection of the distinguishable amplicons can be varied in each of the steps of the method, which expands the dynamic range of the nucleic acid quantification methods and improves the reliability and accuracy of the methods.

Abstract: Methods and compositions for inhibiting and/or inactivating nucleases by employing nuclease inhibitors are provided. The nuclease inhibitors comprise anti-nuclease antibodies and non-antibody nuclease inhibitors. The anti-nuclease antibodies of the present invention may be a polyclonal or monoclonal antibodies, and may be anti-ribonuclease antibodies, anti-deoxyribonuclease antibodies, or antibodies to non-specific nucleases. A preferred embodiment comprises at least two nuclease inhibitors, and is referred to as a nuclease inhibitor cocktail. In some specific embodiments, the invention concerns methods of performing in vitro translation comprising obtaining a first nuclease inhibitor, which inhibitor is further defined as an anti-nuclease antibody, and placing the anti-nuclease antibody in an in vitro translation reaction. In many cases, the in vitro translation reaction comprises at least one nuclease, which may be a ribonuclease, a deoxyribonuclease, or a nonspecific nuclease.

Abstract: The present invention relates to nuclease resistant nucleic acids in general and ribonuclease resistant RNAs in particular. Methods of making and using such nucleic acids are disclosed.

Abstract: Methods and compositions for probe amplification to detect, identify, quantitate, and/or analyze a targeted nucleic acid sequence. After hybridization between a probe and the targeted nucleic acid, the probe is modified to distinguish hybridized probe from unhybridized probe. Thereafter, the probe is amplified. Moreover, in specific embodiments, the present invention involves a chimeric probe that is particularly effective when the targeted nucleic acid sequence is short and/or has a relatively low concentration, such as with an miRNA molecule.

Abstract: A surgical dissector comprising an elongate shaft having a proximal end and a distal end. A blunt dissection tip is positioned on the distal end of the elongate shaft. A light source emits a diffuse visible energy, such as white light, from the blunt tip. The shaft may take a variety of shapes, including being rigid, flexible, malleable, straight, bent, curved, articulated, and/or segmented. In addition, the shaft may include one or more functional components. The dissector can be used to locate the dissector tip by observing the visible energy passing through tissue. In addition, the visible energy passing through tissue may be used to differentiate tissue.

Abstract: The present invention is directed to compositions and methods for removal of nucleic acid probes from sample nucleic acids, particularly when the sample nucleic acids are attached to a solid support. The invention also concerns methods of stripping and reusing nucleic acid blots.

Abstract: Methods and compositions for inhibiting and/or inactivating nucleases by employing nuclease inhibitors are provided. The nuclease inhibitors comprise anti-nuclease antibodies and non-antibody nuclease inhibitors. The anti-nuclease antibodies of the present invention may be a polyclonal or monoclonal antibodies, and may be anti-ribonuclease antibodies, anti-deoxyribonuclease antibodies, or antibodies to non-specific nucleases. A preferred embodiment comprises at least two nuclease inhibitors, and is referred to as a nuclease inhibitor cocktail. In some specific embodiments, the invention concerns methods of performing in vitro translation comprising obtaining a first nuclease inhibitor, which inhibitor is further defined as an anti-nuclease antibody, and placing the anti-nuclease antibody in an in vitro translation reaction. In many cases, the in vitro translation reaction comprises at least one nuclease, which may be a ribonuclease, a deoxyribonuclease, or a nonspecific nuclease.

Abstract: Methods and compositions for inhibiting and/or inactivating nucleases by using nuclease inhibitors are provided. The nuclease inhibitors comprise anti-nuclease antibodies and non-antibody nuclease inhibitors.

Abstract: The present invention relates to compositions and methods for increasing the yields of polynucleotide synthetic reactions. In particular, it relates to an improved reaction mixture for use in in vitro RNA trancription and in various other enzymatic reactions in which a polynucleotide is synthesised. The reaction mixture uses high concentrations of total nucleotides, in the order of 12 mM to 40 mM, i.e. levels that were previously thought to be inhibitory. Other useful modifications are also disclosed.

Abstract: The present invention relates to compositions and methods for increasing the yields of polynucleotide synthetic reactions. In particular, it relates to an improved reaction mixture for use in in vitro RNA trancription and in various other enzymatic reactions in which a polynucleotide is synthesised. The reaction mixture uses high concentrations of total nucleotides, in the order of 12 mM to 40 mM, i.e. levels that were previously thought to be inhibitory. Other useful modifications are also disclosed.

Abstract: The present invention relates to compositions and methods for increasing the yields of polynucleotide synthetic reactions. In particular, it relates to an improved reaction mixture for use in in vitro RNA trancription and in various other enzymatic reactions in which a polynucleotide is synthesized. The reaction mixture uses high concentrations of total nucleotides, in the order of 12 mM to 40 mM, i.e. levels that were previously thought to be inhibitory. Other useful modifications are also disclosed.

Abstract: The present invention relates to compositions and methods for increasing the yields of polynucleotide synthetic reactions. In particular, it relates to an improved reaction mixture for use in in vitro RNA trancription and in various other enzymatic reactions in which a polynucleotide is synthesised. The reaction mixture uses high concentrations of total nucleotides, in the order of 12 mM to 40 mM, i.e. levels that were previously thought to be inhibitory. Other useful modifications are also disclosed.