Abstract: A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharmaceutical package that reduces the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution contained.

Abstract: A composite material having a substrate material and at least one barrier coating on one side of the substrate material. The barrier coating is plasma impulse chemical vapor deposited (PICVD) to the substrate material. The barrier coating includes at least one of material selected from the group consisting of SiOx, TiOx, SnOx, Si3Ny, Nb2Oy, and Al2Oy.

Abstract: A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharmaceutical package that reduces the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution contained.

Abstract: The invention relates to an apparatus and a method for the coating of hollow bodies, in particular for the internal coating of plastic drinks bottles by means of a PICVD. It is an object of the invention to ensure a flexible process sequence, a high throughput, an improved supply of fluid and a high-quality coating. The invention in particular proposes a rotary apparatus which comprises a treatment device with double reactors for receiving in each case at least one workpiece, a fluid supply apparatus and at least one fluid control device, which can be used to control the supply of fluid to the treatment device. It is preferable for the vacuum pumps to be arranged on the rotor such that they rotate therewith.

Abstract: The invention relates to a method and an apparatus for the treatment of substrates, in particular for the coating of plastic containers on a rotary installation. A plurality of treatment devices are arranged on the rotor and pass through a plurality of process phases as a function of their angle position on the rotor. For at least one process phase, the angle position can be set variably as a function of the current rotational speed of the rotor.

Abstract: A method and a device (MON) for monitoring plasma-discharges during a surface treatment process are described. In this process electrodes within a gaseous medium are provided with an alternating voltage (UHV) for generating plasma. The monitoring device (MON) has a detector device (M1) for detecting a measurement signal (I) generated by the alternating voltage (UHV) within the gaseous medium, separating means (M2) for separating signal components above a preset frequency and evaluating means (M3) for evaluating the resulting separated signal components by comparing them with at least one preset reference. Preferably the generating of the plasma is achieved by dielectric barrier discharge and the electric current penetrating the medium, especially the dielectric displacement current, is measured as the measurement signal (I).

Abstract: A process for simultaneously coating and forming a body. The process includes moving two mold halves into contact with one another; introducing an injection-molding material into the mold halves so that a molding is formed; evacuating the molding; admitting a gas into the molding; igniting a plasma in the molding so that a coating is deposited on the inner side of the molding; and moving the mold halves apart so that the molding drops out.

Abstract: The invention relates to a method and a device which are used for the plasma treatment of work pieces. Said work piece is inserted into an at least partially evacuatable chamber of a treatment station (3) and the work piece is positioned inside the treatment station of retaining elements. At least one operating agent is at least partially impinged upon by a transporting device (44) which is displaced together with the treatment station on a closed and rotating transport path.

Abstract: In order to improve the emptying of residual contents from containers, such as pharmaceutical packaging, the invention provides corresponding substrates with a hydrophobic coating. Provided for this purpose is a composite material which comprises a substrate and a coating deposited on it, which forms at least a part of the surface of the coated substrate, with the coating having a compound containing the elements C, O, and H, with further elements, apart from Si, C, H, having a content of less than 10 at %, preferably less than 5 at %, characterized in that this compound has a composition SiOxCyHz, in which x is at most 1.2.

Abstract: The present invention relates to a multi-functional pharmaceutical package surface and a method of preparing a multi-functional pharmaceutical package surface. In particular, the present invention relates to a pharmaceutical package having a protein deterrent and lubricious surface and methods of preparing said surface by applying coatings directly to the pharmaceutical package that (a) reduce the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution and (b) provide a lubricious surface. The pharmaceutical package surface may also contain a barrier coating. Coatings can be deposited on a variety of pharmaceutical packaging materials and configurations by various methods.

Abstract: The invention relates to a method for producing layers on work pieces (30) in which at least one component for producing the layer is metered, wherein this component is located in liquid phase during the metering and is transformed at least partially into a different aggregate state in a subsequent processing step.

Abstract: The invention relates to a method for the plasma treatment of workpieces, particularly workpieces in the form of hollow bodies, in which a treatment zone in a reactor chamber is at least partially evacuated, a process gas is introduced into the treatment zone, particularly into the cavity of the workpiece, and a plasma is ignited by means of injected electromagnetic energy in the process gas introduced into the treatment zone, wherein the process gas flows through the treatment zone between opposite ends of the zone during the plasma treatment.

Abstract: The controller and method of the invention generate control instructions for a rotary machine that coats bottles. Gas is supplied to processing stations holding the bottles via a pressure management system. The processing stations are centrally controlled by a programmable PLC or microcontroller with an input device and display terminal. Since rotary machines need to be controlled differently depending on the type of bottles and the type of coating, different programs should be interactively created using the input device and display terminal, which then control the individual components of the rotary machine and the processing stations during the coating process. This eliminates unnecessary errors resulting from preparation of the different programs individually by a normal user.

Abstract: A process for applying alternating layers by chemical vapor deposition comprises the process steps of depositing an adhesion-promoter layer on a substrate and applying a barrier layer. Alternating layers comprising organic and inorganic materials are deposited alternately, and in this process the coating time for application of the adhesion-promoter layer is between 0.05 s and 4.0 s and the coating time for application of the inorganic barrier layer is between 0.1 s and 6.0 s. A composite material is also produced using the process.

Abstract: The invention relates to a method for the plasma treatment of glass surfaces, the metal component, in particular the alkali and/or alkaline-earth metal component in the superficial region of the substrate being reduced by a plasma treatment of a substrate.

Abstract: A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharmaceutical package that reduces the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution contained.

Abstract: In order to allow a continuous production process for the plasma treatment of workpieces, an apparatus for plasma treatment of workpieces is provided which comprises a transport device and a plasma generating device which injects electromagnetic energy into an area of the apparatus during operation, in which the transport device carries the workpieces through the area continuously.

Abstract: The invention relates to a device and a method for generating control instructions for a rotary machine, wherein processing stations are disposed on a rotary machine. In the preferred embodiment, the processing stations have holders for receiving bottles. Furthermore, gas is supplied via the processing stations and via the pressure management system. The processing stations can be controlled centrally by a PLC, by respectively one separate PLC or by specific microcontrollers. Said components can be programmed by code instructions. A further component of the device is an input and display terminal by which means the programs are created interactively. This is preferably a laptop with a windowed interface such as Windows®. Since rotary machines need to be controlled differently depending on the type of bottles and the type of coating, different programs should be created which then control the individual components of the rotary machine and the processing stations.

Abstract: To improve a biodegradable plastic substrate by applying a coating, the invention provides a process for producing a composite material in which a biodegradable plastic substrate is provided, which is coated on at least one surface with at least one barrier layer, the barrier layer being deposited by chemical vapor deposition.

Abstract: An apparatus and a method for the coating of hollow bodies, in particular for the internal coating of plastic drinks bottles by means of a PICVD is provided. The method ensures a flexible process sequence, a high throughput, an improved supply of fluid and a high-quality coating. The rotary apparatus includes a treatment device with double reactors for receiving in each case at least one workpiece, a fluid supply apparatus and at least one fluid control device, which can be used to control the supply of fluid to the treatment device. It is preferable for the vacuum pumps to be arranged on the rotor such that they rotate therewith.