Patents by Inventor Matthias Corbascio

Matthias Corbascio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivation and self-renewal of ISI1+ cells and uses thereof
    Patent number: 11607429
    Abstract: The present invention relates to methods for deriving multipotent Isl1+ cells (i.e. methods for inducing a cell to enter a multipotent Isl1+ lineage), methods for differentiating Isl1+ cells to cardiac cells, cells obtainable by such methods, kits and compositions for carrying out the methods in accordance with the invention, and also medical applications and pharmaceutical compositions of said cells.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: March 21, 2023
    Assignee: Swedish StromaBio AB
    Inventors: Karl Henrik-Grinnemo, Oscar Simonson, Matthias Corbascio, Christer Sylvén, Eva Wärdell
  • Immunomodulatory compositions
    Patent number: 10751370
    Abstract: The present invention relates to pharmaceutical compositions comprising mesenchymal cells (MSCs) and additional agents for blocking co-stimulation of the immune system. The compositions may optionally further comprise a therapeutic cell, a therapeutic tissue, and/or a therapeutic organ implant. Additionally, the instant invention pertains to medical uses of such compositions in immune-mediated diseases and disorders, in essentially all inflammatory and/or autoimmune diseases and conditions, and also in transplantation-related conditions.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: August 25, 2020
    Assignee: Swedish Stromabio AB
    Inventors: Matthias Corbascio, Makiko Kumagai
  • DERIVATION AND SELF-RENEWAL OF ISI1+ CELLS AND USES THEREOF
    Publication number: 20190290700
    Abstract: The present invention relates to methods for deriving multipotent Isl1+ cells (i.e. methods for inducing a cell to enter a multipotent Isl1+ lineage), methods for differentiating Isl1+ cells to cardiac cells, cells obtainable by such methods, kits and compositions for carrying out the methods in accordance with the invention, and also medical applications and pharmaceutical compositions of said cells.
    Type: Application
    Filed: March 11, 2019
    Publication date: September 26, 2019
    Applicant: ISLETONE AB
    Inventors: Karl HENRIK-GRINNEMO, Oscar SIMONSON, Matthias CORBASCIO, Christer SYLVÉN, Eva WÄRDELL
  • Derivation and self-renewal of lsl1+ cells and uses thereof
    Patent number: 10226487
    Abstract: The present invention relates to methods for deriving multipotent Isl1+ cells (i.e. methods for inducing a cell to enter a multipotent Isl1+ lineage), methods for differentiating Isl1+ cells to cardiac cells, cells obtainable by such methods, kits and compositions for carrying out the methods in accordance with the invention, and also medical applications and pharmaceutical compositions of said cells.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: March 12, 2019
    Assignee: IsletOne AB
    Inventors: Karl-Henrik Grinnemo, Oscar Simonson, Matthias Corbascio, Christer Sylvén, Eva Wärdell
  • IMMUNOMODULATORY COMPOSITIONS
    Publication number: 20160361364
    Abstract: The present invention relates to pharmaceutical compositions comprising mesenchymal cells (MSCs) and additional agents for blocking co-stimulation of the immune system. The compositions may optionally further comprise a therapeutic cell, a therapeutic tissue, and/or a therapeutic organ implant. Additionally, the instant invention pertains to medical uses of such compositions in immune-mediated diseases and disorders, in essentially all inflammatory and/or autoimmune diseases and conditions, and also in transplantation-related conditions.
    Type: Application
    Filed: December 11, 2014
    Publication date: December 15, 2016
    Applicant: ISLETONE AB
    Inventors: Matthias CORBASCIO, Makiko KUMAGAI
  • DERIVATION AND SELF-RENEWAL OF ISI1+ CELLS AND USES THEREOF
    Publication number: 20150164958
    Abstract: The present invention relates to methods for deriving multipotent Isl1+ cells (i.e. methods for inducing a cell to enter a multipotent Isl1+ lineage), methods for differentiating Isl1+ cells to cardiac cells, cells obtainable by such methods, kits and compositions for carrying out the methods in accordance with the invention, and also medical applications and pharmaceutical compositions of said cells.
    Type: Application
    Filed: July 11, 2013
    Publication date: June 18, 2015
    Applicant: IsletOne AB
    Inventors: Karl-Henrik Grinnemo, Oscar Simonson, Matthias Corbascio, Christer Sylvén, Eva Wärdell