Abstract: Herein disclosed are methods that are prognostic for neoplastic/preneoplastic disease in a subject vertebrate, wherein said disease is associated with a tissue that normally expresses MN, but which MN expression is lost or diminished upon carcinogenesis. Exemplary of the types of preneoplastic/neoplastic diseases subject to the prognostic methods of this invention are those of gastric mucosa, gallbladder, biliary ducts, and ductal cells of duodenal glands. An exemplary prognostic method comprises comparing the level of MN gene expression product in a tissue sample from the affected subject, with the average MN gene expression product level found in analogous preneoplastic/neoplastic tissue samples; an above average MN gene expression product level indicates poorer prognosis for the subject. MN gene expression products useful in the prognostic methods include MN protein, MN polypeptide, and/or MN nucleic acids.

Abstract: Herein disclosed are methods that are prognostic for neoplastic/preneoplastic disease in a subject vertebrate, wherein said disease is associated with a tissue that normally expresses MN, but which MN expression is lost or diminished upon carcinogenesis. Exemplary of the types of preneoplastic/neoplastic diseases subject to the prognostic methods of this invention are those of gastric mucosa, gallbladder, biliary ducts, and ductal cells of duodenal glands. An exemplary prognostic method comprises comparing the level of MN gene expression product in a tissue sample from the affected subject, with the average MN gene expression product level found in analogous preneoplastic/neoplastic tissue samples; an above average MN gene expression product level indicates poorer prognosis for the subject. MN gene expression products useful in the prognostic methods include MN protein, MN polypeptide, and/or MN nucleic acids.

Abstract: The invention provides methods, nucleic acids and kits for detecting, or for distinguishing between or among colorectal cell proliferative disorders. The invention discloses genomic sequences the methylation patterns of which have utility for the improved detection of and differentiation between said class of disorders, thereby enabling the improved diagnosis and treatment of patients.

Abstract: In order to make it possible to detect a fault location, safely, reliably and with a high response sensitivity, in a braided wire which has a plurality of individual wires, an electric current is passed through the braided wire and the magnetic field which is formed as a result of the braided wire through which current flows is detected by a sensor and is evaluated. A fault location is deduced if the measured magnetic field has an oscillation whose length is a multiple of a lay length of the braided wire, and in particular corresponds to the lay length. The method is also used in particular for non-destructive testing of the quality of a contact connection of a contact element to the braided wire.

Abstract: Herein disclosed are methods that are prognostic for neoplastic/preneoplastic disease in a subject vertebrate, wherein said disease is associated with a tissue that normally expresses MN, but which MN expression is lost or diminished upon carcinogenesis. Exemplary of the types of preneoplastic/neoplastic diseases subject to the prognostic methods of this invention are those of gastric mucosa, gallbladder, biliary ducts, and ductal cells of duodenal glands. An exemplary prognostic method comprises comparing the level of MN gene expression product in a tissue sample from the affected subject, with the average MN gene expression product level found in analogous preneoplastic/neoplastic tissue samples; an above average MN gene expression product level indicates poorer prognosis for the subject. MN gene expression products useful in the prognostic methods include MN protein, MN polypeptide, and/or MN nucleic acids.

Abstract: Herein disclosed are methods that are prognostic for neoplastic/preneoplastic disease in a subject vertebrate, wherein said disease is associated with a tissue that normally expresses MN, but which MN expression is lost or diminished upon carcinogenesis. Exemplary of the types of preneoplastic/neoplastic diseases subject to the prognostic methods of this invention are those of gastric mucosa, gallbladder, biliary ducts, and ductal cells of duodenal glands. An exemplary prognostic method comprises comparing the level of MN gene expression product in a tissue sample from the affected subject, with the average MN gene expression product level found in analogous preneoplastic/neoplastic tissue samples; an above average MN gene expression product level indicates poorer prognosis for the subject. MN gene expression products useful in the prognostic methods include MN protein, MN polypeptide, and/or MN nucleic acids.

Abstract: The invention provides methods, nucleic acids and kits for detecting colon cell proliferative disorders. The invention discloses genomic sequences the methylation patterns of which have utility for the improved detection of and differentiation between said class of disorders, thereby enabling the improved diagnosis and treatment of patients.

Abstract: An active dynamic seating device is provided that includes a seat, a central part and a base part, where a stable sitting position is attained by additionally supporting one or both legs of a user. The seating device encompasses a tone generator, which emits a tone in response to carrying out a certain change of the sitting position. The seating device is particularly well-suited for, for example, carrying out gymnastics exercises.

Abstract: Herein disclosed are methods that are prognostic for neoplastic/preneoplastic disease in a subject vertebrate, wherein said disease is associated with a tissue that normally expresses MN, but which MN expression is lost or diminished upon carcinogenesis. Exemplary of the types of preneoplastic/neoplastic diseases subject to the prognostic methods of this invention are those of gastric mucosa, gallbladder, biliary ducts, and ductal cells of duodenal glands. An exemplary prognostic method comprises comparing the level of MN gene expression product in a tissue sample from the affected subject, with the average MN gene expression product level found in analogous preneoplastic/neoplastic tissue samples; an above average MN gene expression product level indicates poorer prognosis for the subject. MN gene expression products useful in the prognostic methods include MN protein, MN polypeptide, and/or MN nucleic acids.

Abstract: A method for producing a reliable and permanent electrical connection between an aluminum conductor and a contact element includes melting a supply of a contact-making material and forming a cohesive material connection between the aluminum conductor and the contact element by subsequent solidification in order to form the electrical connection. In order to ensure that the functions of electrical contact-making and strain relief do not interact with one another in a disadvantageous manner, the contact element is shaped to form the mechanical strain relief, after the formation of the electrical contact.

Abstract: The invention relates to a method and a device for reconstructing an image in a spatial volume on the basis of acquired projections, wherein during a reconstruction step each acquired projection or each region of an acquired projection is fed once into a data processing system from a memory for the acquired projections and intensity of a voxel of the reconstructed spatial volume image is updated during the reconstruction step for each voxel relevant projection or region.

Abstract: The invention relates to a method and a device for reconstructing an image in a spatial volume on the basis of acquired projections, wherein during a reconstruction step each acquired projection or each region of an acquired projection is fed once into a data processing system from a memory for the acquired projections and the intensity of a voxel of the reconstructed spatial volume image is updated during the reconstruction step for each voxel relevant projection or region.