Abstract: Method for detecting at least one target substance, including converting molecules of at least one of the target substances to a gaseous state and a spectrometric detection of the molecules. The object is to significantly increase the resolving capacity of the method in its detection limit and in its selectivity. This is achieved in that the conversion includes soluble mixing, formation of aerosol and evaporation of at least one of the target substances with a solvent, the molecules being integrated into a gas phase, and the spectrometric detection includes an ionisation of the molecules in the gas phase to form ions.