Abstract: A method for protected communication between a mobile unit coupled to a smartphone and a server, wherein it is possible to access a service of the server via the smartphone by registration data. Processes are provided for the first-time input of a PIN number in association with the registration data; definition of a secret of the mobile unit; storage of the registration data; the PIN number and the secret in a secure memory in the smartphone; input of the PIN number on the mobile unit; transmission of the PIN number and the secret from the mobile unit to the secure memory; reading of at least a portion of the registration data from the secure memory if the transmitted PIN number and the transmitted secret match the stored PIN number and the stored secret; and transmission of at least the portion of the registration data from the smartphone to the server.

Abstract: A method for preventing deactivation of online services in a vehicle. The method includes generating a configuration message that contains details of what online services that are active in the vehicle cannot be deactivated, wherein the generation takes place on a computer unit that is at least temporarily connected to the vehicle; transmitting the configuration message to the vehicle; reading the configuration message in the vehicle; and disabling the option of deactivating online services in the vehicle in accordance with the configuration message.

Abstract: In a method for informing a driver of a vehicle regarding the availability of a communication link of the vehicle to an external communication unit, a first service category and a second service category are provided which utilize the communication link, the availability of the communication link is checked for both service categories, and the result of the availability check is displayed graphically to the vehicle driver in one symbol for both service categories.

Abstract: A method for protected communication between a mobile unit coupled to a smartphone and a server, wherein it is possible to access a service of the server via the smartphone by registration data. Processes are provided for the first-time input of a PIN number in association with the registration data; definition of a secret of the mobile unit; storage of the registration data; the PIN number and the secret in a secure memory in the smartphone; input of the PIN number on the mobile unit; transmission of the PIN number and the secret from the mobile unit to the secure memory; reading of at least a portion of the registration data from the secure memory if the transmitted PIN number and the transmitted secret match the stored PIN number and the stored secret; and transmission of at least the portion of the registration data from the smartphone to the server.

Abstract: In a method for informing a driver of a vehicle regarding the availability of a communication link of the vehicle to an external communication unit, a first service category and a second service category are provided which utilize the communication link, the availability of the communication link is checked for both service categories, and the result of the availability check is displayed graphically to the vehicle driver in one symbol for both service categories.

Abstract: In a method for informing a driver of a vehicle regarding the availability of a communication link of the vehicle to an external communication unit, a first service category and a second service category are provided which utilize the communication link, the availability of the communication link is checked for both service categories, and the result of the availability check is displayed graphically to the vehicle driver in one symbol for both service categories.

Abstract: A method for preventing deactivation of online services in a vehicle. The method includes generating a configuration message that contains details of what online services that are active in the vehicle cannot be deactivated, wherein the generation takes place on a computer unit that is at least temporarily connected to the vehicle; transmitting the configuration message to the vehicle; reading the configuration message in the vehicle; and disabling the option of deactivating online services in the vehicle in accordance with the configuration message.

Abstract: In a method for informing a driver of a vehicle regarding the availability of a communication link of the vehicle to an external communication unit, a first service category and a second service category are provided which utilize the communication link, the availability of the communication link is checked for both service categories, and the result of the availability check is displayed graphically to the vehicle driver in one symbol for both service categories.

Abstract: The present invention describes a process for the selective synthesis of N-Fmoc-doxorubicin-14-O-dicarboxylic acid mono ester derivatives starting from N-Fmoc-doxorubicin using lipase enzymes and bis-acyl donor compounds such as dicarboxylic acids or anhydrides.

Abstract: The present invention provides new pyridopyrazine compounds of Formula (I) which are suitable for the treatment or prevention of physiological and/or pathophysiological states mediated and/or modulated by signal transduction pathways and/or enzymes in mammals and in particular in humans.

Abstract: The invention provides new pyridopyrazine compounds according to formula (I) which are highly selective as Ras-Raf-Mek-Erk signal transduction pathway inhibitors and in particular are highly selective Erk inhibitors.

Abstract: A method of modulating one or more of ras-Raf-Mek-Erk signal transduction pathway, PI3K-Akt signal transduction pathway and SAPK signal transduction pathway with 1-ethyl-3-[3-(1-methyl-1H-pyrazol-4-yl)-pyrido[2,3-b]pyrazine-6-yl]thiourea, its geometric isomer, or its tautomer.

Abstract: The present invention provides novel triazole derivatives with improved receptor activity and bioavailability properties as ghrelin analogue ligands of growth hormone secretagogue receptors according to formula (I) that are useful in the treatment or prophylaxis of physiological and/or pathophysiological conditions in mammals, preferably humans, that are mediated by GHS receptors.

Abstract: Method of modulating ras-Raf-Mek-Erk signal transduction pathway, PI3K-Akt signal transduction pathway and/or SAPK signal transduction pathway with a pyrido[2,3-b]pyrazine of formula (Ia).

Abstract: 1-ethyl-3-[3-(1-methyl-1H-pyrazol-4-yl)-pyrido[2.3-b]pyrazine-6-yl]thiourea which HAS activity to the modulation of misdirected cellular signal transduction processes such as tyrosine kinases, serine/threonine kinases and/or lipid kinases.

Abstract: The present invention relates to kinase modulators of the naphthyridine type and to the preparation and use thereof as medicaments for the modulation of misdirected cellular signal transduction processes, in particular for influencing the function of tyrosine and serine/threonine kinases and for the treatment of malignant or benign tumors and other disorders based on pathological cell proliferation, such as, for example, restenosis, psoriasis, arteriosclerosis and cirrhosis of the liver.

Abstract: The invention provides quinoxalines of the general formula I which are used as medicaments preferably for treating tumour disorders, in particular in cases of drug resistance to other active compounds and in cases of metastasic carcinoma. The possible applications are not limited to tumour disorders.

Abstract: The invention relates to pyrido[2,3-b]pyrazine compounds of general formulae (Ia) and (Ib), to their preparation and use, for example, for the treatment of malignant disorders and other disorders based on pathological cell proliferations.

Abstract: The present invention provides new pyridopyrazine compounds which are suitable for the treatment or prevention of physiological and/or pathophysiological states mediated and/or modulated by signal transduction pathways and/or enzymes in mammals and in particular in humans.

Abstract: The present invention provides new pyridopyrazine compounds which are suitable for the treatment or prevention of physiological and/or pathophysiological states mediated and/or modulated by signal transduction pathways and/or enzymes in mammals and in particular in humans.