Patents by Inventor Matthias Gratz

Matthias Gratz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9849005
    Abstract: A method for manufacturing an implant and an implant, in particular an intraluminal endoprosthesis, including a body having a coating on at least a portion of the surface thereof, and the degradation of which can be influenced from the outside in a targeted manner, the method having the following steps: a) providing an implant body, and b) applying a coating to the surface of the implant body, wherein the coating comprises unfilled cavities, preferably in the form of microbubbles (2).
    Type: Grant
    Filed: April 8, 2013
    Date of Patent: December 26, 2017
    Assignee: Biotronik AG
    Inventors: Robert Schmiedl, Matthias Gratz, Max Schaldach, Volker Lang
  • Patent number: 9452243
    Abstract: The invention relates to an implant comprising an active-agent-containing coating which covers the implant at least in sections. The coating is composed of at least two subsections; a first subsection contains the at least one active substance, and a second subsection contains an auxiliary agent.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: September 27, 2016
    Assignee: BIOTRONIK AG
    Inventors: Matthias Gratz, Alexander Borck, Alexander Rzany, Robert Schmiedl, Matthias Fringes, Claus Harder
  • Patent number: 9138512
    Abstract: The present invention refers to an implant with a surface layer having a topographic modification. The topographic modification includes a line pattern with ridge and groove widths of 0.9 to 1.1 ?m and a ridge height of more than 0.9 ?m.
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: September 22, 2015
    Assignee: Biotronik AG
    Inventors: Aldo Ferrari, Vartan Kurtcuoglu, Philipp Schoen, Jens Ulmer, Alexander Borck, Matthias Gratz, Alexander Rzany, Robert Schmiedl, Dimos Poulikakos, Bjoern Klocke
  • Patent number: 8961592
    Abstract: At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: February 24, 2015
    Assignee: Biotronik AG
    Inventors: Alexander Borck, Matthias Gratz, Horst Kessler, Michael Joner, Florian Rechenmacher, Stefanie Neubauer
  • Publication number: 20140222134
    Abstract: At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method.
    Type: Application
    Filed: April 14, 2014
    Publication date: August 7, 2014
    Applicant: BIOTRONIK AG
    Inventors: Alexander Borck, Matthias Gratz, Horst Kessler, Michael Joner, Florian Rechenmacher, Stefanie Neubauer
  • Patent number: 8728496
    Abstract: At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: May 20, 2014
    Assignee: Biotronik AG
    Inventors: Alexander Borck, Matthias Gratz, Horst Kessler, Michael Joner, Florian Rechenmacher, Stefanie Neubauer
  • Publication number: 20130274869
    Abstract: A method for manufacturing an implant and an implant, in particular an intraluminal endoprosthesis, including a body having a coating on at least a portion of the surface thereof, and the degradation of which can be influenced from the outside in a targeted manner, the method having the following steps: a) providing an implant body, and b) applying a coating to the surface of the implant body, wherein the coating comprises unfilled cavities, preferably in the form of microbubbles (2).
    Type: Application
    Filed: April 8, 2013
    Publication date: October 17, 2013
    Applicant: BIOTRONIK AG
    Inventors: Robert Schmiedl, Matthias Gratz, Max Schaldach, Volker Lang
  • Publication number: 20120150281
    Abstract: The invention relates to an implant having a base body made of a biocorrodible material. A surface of the implant has a coating at least in some regions, wherein the coating comprises a tissue adhesive.
    Type: Application
    Filed: December 6, 2011
    Publication date: June 14, 2012
    Inventors: Bjoern Klocke, Matthias Gratz
  • Publication number: 20120150284
    Abstract: The invention relates to an implant comprising an active-agent-containing coating which covers the implant at least in sections. The coating is composed of at least two subsections; a first subsection contains the at least one active substance, and a second subsection contains an auxiliary agent.
    Type: Application
    Filed: November 29, 2011
    Publication date: June 14, 2012
    Applicant: BIOTRONIK AG
    Inventors: Matthias Gratz, Alexander Borck, Alexander Rzany, Robert Schmiedl, Matthias Fringes, Claus Harder
  • Publication number: 20120121659
    Abstract: At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 17, 2012
    Applicant: BIOTRONIK AG
    Inventors: Alexander Borck, Matthias Gratz, Horst Kessler, Michael Joner, Florian Rechenmacher, Stefanie Neubauer
  • Publication number: 20120121658
    Abstract: At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 17, 2012
    Applicant: BIOTRONIK AG
    Inventors: Alexander Borck, Matthias Gratz, Horst Kessler, Michael Joner, Florian Rechenmacher, Stefanie Neubauer
  • Publication number: 20120053677
    Abstract: The present invention refers to an implant with a surface layer having a topographic modification. The topographic modification includes a line pattern with ridge and groove widths of 0.9 to 1.1 ?m and a ridge height of more than 0.9 ?m.
    Type: Application
    Filed: August 25, 2011
    Publication date: March 1, 2012
    Applicant: BIOTRONIK AG
    Inventors: Aldo Ferrari, Vartan Kurtcuoglu, Philipp Schoen, Jens Ulmer, Alexander Borck, Matthias Gratz, Alexander Rzany, Robert Schmiedl, Dimos Poulikakos, Bjoern Klocke
  • Publication number: 20110307054
    Abstract: One example embodiment of the present invention relates to an implant with a coating or a cavity filling containing a nucleic acid, which i) can inhibit the expression of at least one representative of the Ras gene family by means of RNA interference; or ii) encodes for a nucleic acid that can inhibit the expression of at least one representative of the Ras gene family by means of RNA interference.
    Type: Application
    Filed: December 3, 2010
    Publication date: December 15, 2011
    Inventors: Alexander Borck, Matthias Gratz
  • Publication number: 20110244016
    Abstract: One embodiment of the invention relates to a medical implant whose surface is completely or partially covered by a coating composed of at least one active substance or containing at least one active substance.
    Type: Application
    Filed: March 24, 2011
    Publication date: October 6, 2011
    Inventors: Matthias Gratz, Alexander Borck, Kathleen Koeck
  • Publication number: 20100119581
    Abstract: The present invention concerns medical products that release pharmaceutically active substances, the efficiency of which is increased as the result of a combination with an inhibitor of the transport protein P-glycoprotein.
    Type: Application
    Filed: November 5, 2009
    Publication date: May 13, 2010
    Applicant: BIOTRONIK VI PATENT AG
    Inventors: Matthias Gratz, Alexander Borck
  • Publication number: 20100015201
    Abstract: The present invention concerns an implant with a molecularly imprinted polymer coating, a process for its synthesis, a molecularly imprinted polymer, as well as a process for its synthesis and its use as well as a process for the treatment or prophylaxis of certain disease conditions by implantation of an implant in accordance with the invention according to the respective independent claims.
    Type: Application
    Filed: July 17, 2009
    Publication date: January 21, 2010
    Inventors: Alexander Borck, Matthias Gratz
  • Patent number: 4705290
    Abstract: Running sole structuring for a ski, especially for a cross-country ski.The object of the invention is to provide a new profiling which combines optimum gliding and climbing characteristics. Therefore, it is the object of the invention, to provide a suitable shaping of the profiling which fully considers the special requirements under different snow conditions as well as the special loadings of the ski during the push-off and gliding phases, as well as the process of sticking and gliding friction and the transitional phases associated therewith directly.This object is solved according to the invention by the provision of exclusively straight, vertical and parallel arranged profile edges with respect to the direction of the run which are also two-dimensional in the plane of contact with the snow and are statistically arranged and, wherein the adjacent pairs of climbing edge rows lying behind each other lie on a gliding arc. It is preferred when the mean edge length (b.sub.
    Type: Grant
    Filed: March 6, 1987
    Date of Patent: November 10, 1987
    Inventors: Matthias Gratz, Schmalz Hans-Dieter, Gerald Stadler, Lothar Hildenbrandt