Patents by Inventor Matthias Helmreich

Matthias Helmreich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the separation of enantiomers of 3,6-dihydro-1,3,5-triazine derivatives
    Patent number: 8895732
    Abstract: Method for the chromatographic separation of compounds of the formula (I), in which R1, R2, R3, R4, R5, R6 have the meanings indicated in Claim 1, and acid-addition salts thereof, characterized in that the separation is carried out on a chiral ion-exchanger material.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: November 25, 2014
    Assignee: Merck Patent GmbH
    Inventors: Matthias Helmreich, Claus Peter Niesert, Michael Schulte, Wolfgang Lindner, Michael Laemmerhofer, Christian Hoffmann
  • Process for enantiomeric separation of racemic dihydro-1,3,5 triazines via preferential crystallization
    Patent number: 8742102
    Abstract: A new process for the enantiomeric separation of racemic 3,6-dihydro-1,3,5-triazine derivatives for the treatment of disorders associated with insulin-resistance syndrome, by preferential crystallization.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: June 3, 2014
    Assignee: Poxel
    Inventors: Matthias Helmreich, Claus-Peter Niesert, Daniel Cravo, Gérard Coquerel, Guillaume Levilain, Saoussen Wacharine-Antar, Pascal Cardinael
  • Separation of triazine derivatives enantiomers using tartaric acid
    Patent number: 8742103
    Abstract: The present invention relates to a new process of separation of triazine derivatives enantiomers involving tartaric acid.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: June 3, 2014
    Assignee: Poxel
    Inventors: Daniel Cravo, Matthias Helmreich
  • SEPARATION OF TRIAZINE DERIVATIVES ENANTIOMERS USING TARTARIC ACID
    Publication number: 20130261300
    Abstract: The present invention relates to a new process of separation of triazine derivatives enantiomers involving tartaric acid.
    Type: Application
    Filed: November 30, 2011
    Publication date: October 3, 2013
    Applicant: POXEL
    Inventors: Daniel Cravo, Matthias Helmreich
  • Method for the production of 3,6-dihydro-L, 3, 5-triazine derivatives from metformin and paraldehyde derivatives
    Patent number: 8461331
    Abstract: Process for the preparation of compounds of the formula I in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in claim 1, which comprises the reaction of a compound of the formula II in which R1, R2, R3, R4 have the meanings indicated above, with a compound of the formula III in which R5, R6 have the meanings indicated above.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: June 11, 2013
    Assignee: Poxel SAS
    Inventors: Matthias Helmreich, Mike Brandner
  • PROCESS FOR ENANTIOMERIC SEPARATION OF RACEMIC DIHYDRO-1,3,5, TRIAZINES VIA PREFERENTIAL CRYSTALLIZATION
    Publication number: 20120071655
    Abstract: A new process for the enantiomeric separation of racemic 3,6-dihydro-1,3,5-triazine derivatives for the treatment of disorders associated with insulin-resistance syndrome, by preferential crystallization.
    Type: Application
    Filed: March 26, 2010
    Publication date: March 22, 2012
    Inventors: Matthias Helmreich, Claus-Peter Niesert, Daniel Cravo, Gérard Coquerel, Gullaume Levilain, Saoussen Wacharine-Antar, Pascal Cardinael
  • Process for the separation of enantiomers of 3,6-dihydro-1,3,5-triazine derivatives
    Publication number: 20120016121
    Abstract: Method for the chromatographic separation of compounds of the formula (I), in which R1, R2, R3, R4, R5, R6 have the meanings indicated in claim 1, and acid-addition salts thereof, characterised in that the separation is carried out on a chiral ion-exchanger material.
    Type: Application
    Filed: February 26, 2010
    Publication date: January 19, 2012
    Inventors: Matthias Helmreich, Claus Peter Niesert, Michael Schulte, Wolfgang Lindner, Michael Laemmerhofer, Christian Hoffmann
  • PROCESS FOR THE SYNTHESIS OF 3,6-DIHYDRO-1,3,5-TRIAZINE DERIVATIVES
    Publication number: 20110124860
    Abstract: A new process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives for the treatment of disorders associated with insulin-resistance syndrome.
    Type: Application
    Filed: April 24, 2009
    Publication date: May 26, 2011
    Inventors: Stéphanie Aubourg, Bernard Boudet, Daniel Cravo, Matthias Helmreich
  • METHOD FOR THE PRODUCTION OF 3,6-DIHYDRO-L, 3, 5-TRIAZINE DERIVATIVES FROM METFORMIN AND PARALDEHYDE DERIVATIVES
    Publication number: 20110118463
    Abstract: Process for the preparation of compounds of the formula I in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in claim 1, which comprises the reaction of a compound of the formula II in which R1, R2, R3, R4 have the meanings indicated above, with a compound of the formula III in which R5, R6 have the meanings indicated above.
    Type: Application
    Filed: January 15, 2009
    Publication date: May 19, 2011
    Inventors: Matthias Helmreich, Mike Brandner