Abstract: The present invention relates to an isolated antibody which specifically binds human PDL1, and pharmaceutical compositions and methods of use thereof. The present invention further relates to a nucleic acid encoding said antibody, a vector comprising said nucleic acid, a host cell comprising said nucleic acid or said vector, and a method of producing said antibody.

Abstract: A PET recycling (the reprocessing of polyethylene terephthalate wastes) has already been practised for many decades in a variety of different ways, since PET is available in large quantities. Environmental protection and sustainability in resource utilization, however, call for ever higher recycling rates in the decades to come. If the concept of a circular economy is to be achieved, this rate must ultimately amount, sooner or later, to 100%.

Abstract: The present invention relates to an isolated antibody which specifically binds human CD137, and pharmaceutical compositions and methods of use thereof. The present invention further relates to a nucleic acid comprising a nucleotide sequence encoding said antibody, a vector comprising said nucleic acid, a host cell comprising said nucleic acid or said vector, and a method of producing said antibody.

Abstract: The present invention relates to a multispecific antibody comprising at least one CD137 binding domain and at least one PDL1 binding domain, and pharmaceutical compositions and methods of use thereof. The present invention further relates to a nucleic acid encoding said multispecific antibody, a vector comprising said nucleic acid, a host cell comprising said nucleic acid or said vector, and a method of producing said multispecific antibody.

Abstract: A device and a method are disclosed for severing a bead of adhesive of a motor vehicle window pane. A cutting wire is firstly introduced into a gap between the window pane and the body flange, the cutting wire then being guided around the bead of adhesive, one first end of said cutting wire preferably being fixed outside the vehicle, preferably to the windshield wiper shaft, the second end of the cutting wire being inserted through the bead of adhesive and fixed to a winding device, and the bead of adhesive is severed by means of the cutting wire by reeling in the cutting wire with the aid of the winding device.

Abstract: The invention provides a device and a method for cutting through an adhesive bead of a pane using a motor-driven winding-up device. The winding-up device includes a coil adapted to wind up a cutting wire for cutting through the adhesive bead and can be coupled, via a coupling that can be disengaged, to a suction disk that can be located on the vehicle inside in such a way that, preferably, the winding-up device is rotatably received on the suction disk. When the winding-up device is driven, it will therefore align itself automatically to the cutting wire.

Abstract: A device and a method are disclosed for severing a bead of adhesive of a motor vehicle window pane. A cutting wire is firstly introduced into a gap between the window pane and the body flange, the cutting wire then being guided around the bead of adhesive, one first end of said cutting wire preferably being fixed outside the vehicle, preferably to the windshield wiper shaft, the second end of the cutting wire being inserted through the bead of adhesive and fixed to a winding device, and the bead of adhesive is severed by means of the cutting wire by reeling in the cutting wire with the aid of the winding device.