Patents by Inventor Matthias Jauslin

Matthias Jauslin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening method and compounds for treating friedreich ataxia
    Publication number: 20050222218
    Abstract: The present invention relates to a method for identifying and/or validating candidate substances for the treatment of Friedreich Ataxia (FRDA). Furthermore, the present invention relates to the use of selenium, Ebselen and Glutathione peroxidase (GPX) mimetics for the preparation of a medicament for the treatment of FRDA. Another aspect of the present invention relates to the use of cells with reduced frataxin expression for identifying and/or validating candidate substances for the treatment of Friedreich Ataxia.
    Type: Application
    Filed: July 1, 2003
    Publication date: October 6, 2005
    Inventors: Thomas Meier, Matthias Jauslin, Fabrice Schoumacher
  • Novel method and assays for yeast-based drug screening
    Publication number: 20050118576
    Abstract: The present invention provides a method wherein yeast mutants deficient in the expression of the yeast homolog of frataxin are applied for the identification and/or evaluation of pharmaceutically active compounds. The invention concerns especially a method wherein the yeast strain W303-1B/?ydl120w::KanR is applied for the identification and/or evaluation of chemical and biochemical compounds that protect W303-1B/?ydl120w::KanR yeast from chemical stress. Furthermore, the invention concerns the application of said method in new cell-based assays to be used for drug screening.
    Type: Application
    Filed: July 11, 2001
    Publication date: June 2, 2005
    Inventors: Thomas Meier, Matthias Jauslin, Claude Nuoffer