Patents by Inventor Matthias Knulle
Matthias Knulle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9914125Abstract: The invention relates to a device for carrying out chemical or biological reactions, having a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, where the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a treating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The reaction vessel receiving element is divided into several segments so that the individual segments are thermally decoupled from one another, and each segment is assigned a heating device which can be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.Type: GrantFiled: September 30, 2013Date of Patent: March 13, 2018Assignee: APPLIED BIOSYSTEMS, LLCInventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Patent number: 8721972Abstract: The invention relates to a device for performing biological reactions in a nucleic acid sample. The device can comprise a reaction vessel receiving element that includes a plurality of reaction vessel holders and a gastight jacket or equalization plate containing a fluid changeable between liquid and gaseous states. The gastight jacket or equalization plate can be configured to provide temperature equalization among the reaction vessel holders. The reaction vessel receiving element can also include at least one Peltier element, a cooling element, and a controller configured to cycle the device through a predetermined time-temperature profile via heating and cooling.Type: GrantFiled: May 14, 2012Date of Patent: May 13, 2014Assignee: Applied Biosystems, LLCInventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Publication number: 20140030170Abstract: The invention relates to a device for the earning out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterised by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.Type: ApplicationFiled: September 30, 2013Publication date: January 30, 2014Applicant: APPLIED BIOSYSTEMS, LLCInventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Patent number: 8389288Abstract: The invention relates to a device for the carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.Type: GrantFiled: January 18, 2010Date of Patent: March 5, 2013Assignee: Applied Biosystems, LLCInventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Publication number: 20120264206Abstract: The invention relates to a device for performing biological reactions in a nucleic acid sample. The device can comprise a reaction vessel receiving element that includes a plurality of reaction vessel holders and a gastight jacket or equalization plate containing a fluid changeable between liquid and gaseous states. The gastight jacket or equalization plate can be configured to provide temperature equalisation among the reaction vessel holders. The reaction vessel receiving element can also include at least one Peltier element, a cooling element, and a controller configured to cycle the device through a predetermined time-temperature profile via heating and cooling.Type: ApplicationFiled: May 14, 2012Publication date: October 18, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Patent number: 7727479Abstract: The invention relates to a device for the carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.Type: GrantFiled: June 12, 2006Date of Patent: June 1, 2010Assignee: Applied Biosystems, LLCInventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Publication number: 20100120099Abstract: The invention relates to a device for the carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterised by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.Type: ApplicationFiled: January 18, 2010Publication date: May 13, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Publication number: 20100120100Abstract: An interactive radio network enables users to interact with the content of a radio broadcast, including commercials or messages, and to selectively save, store, review, fast forward, rewind, pause, forward, and respond to the radio programs and/or the commercials. The interactive radio network provides a widespread, international, and economical access to the radio stations, and reduces the need for advertisement billboards. It provides the users with an opportunity to selectively inquire about the products or services being advertised. Furthermore, the interactive radio network allows the users as well as various sectors of the advertisement industry to interact with the content of the radio broadcast. The advertisements are no longer limited to audio messages, but can further include elaborate video, text, and data information. The interactive radio network enables the users to communicate and interact with each others, based on the broadcast content.Type: ApplicationFiled: January 18, 2010Publication date: May 13, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Patent number: 7611674Abstract: The invention relates to a device for the carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterised by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.Type: GrantFiled: January 11, 2007Date of Patent: November 3, 2009Assignee: Applied Biosystems, LLCInventors: Wolfgang Heimberg, Thomas Hermann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Publication number: 20070140926Abstract: The invention relates to a device for the carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterised by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.Type: ApplicationFiled: January 11, 2007Publication date: June 21, 2007Inventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Publication number: 20070110634Abstract: The invention relates to a device for the carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.Type: ApplicationFiled: January 11, 2007Publication date: May 17, 2007Inventors: Wolfgang Heimberg, Thomas Hermann, Matthias Knulle, Markus Schurf, Tilmann Wagner
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Publication number: 20060228268Abstract: The invention relates to a device for the carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element. The invention is characterised by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others. By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures.Type: ApplicationFiled: June 12, 2006Publication date: October 12, 2006Inventors: Wolfgang Heimberg, Thomas Herrmann, Matthias Knulle, Markus Schurf, Tilmann Wagner