Abstract: The present disclosure relates to a method for producing a shaped sheet metal component from a billet by means of U O forming, wherein firstly a preform is created by the U-forming and then a final shaping is performed by the O forming to give a final form.

Abstract: The invention relates to small molecule imaging tools, specifically compounds of formula II and to pharmaceutically acceptable acid addition salts thereof, wherein R1-R6 have any of the values defined in the specification.

Abstract: A process for preparing the compound of formula I comprising: a) coupling a compound of formula 2 wherein a leaving group O—SO2—R is selected from the triflate group, the tosylate group, the mesylate group, the besylate group, the nosylate group or the brosylate group, with a suitable boronic acid, a trifluoroborate or a boronic acid ester under argon condition and in the presence of a catalyst and a base in a suitable solvent and then isolating the product as an acid addition salt to afford the compound of formula Ia and b) converting the acid addition salt of formula Ia wherein the acid HX comprises suitable organic or inorganic acids into the compound of formula I by treatment with at least a stoichiometric equivalent of a suitable base.

Abstract: The disclosure relates to a method for producing a shaped sheet metal part from a billet by UO forming. First, a preform is created by the U-forming. Then, final forming to give a final form is carried out by the O-forming. The preform has in cross section a maximum width that is smaller than the maximum width of the final form produced after the O-forming.

Abstract: The present invention relates to compounds that may be used for binding and imaging tau aggregates and related beta-sheet aggregates including, besides others, beta-amyloid aggregates or alpha-synuclein aggregates.

Abstract: The invention relates to small molecule imaging tools.

Abstract: The present invention relates to an axle carrier 1 and to a method for the production of the axle carrier 1. The axle carrier 1 has an upper shell 2 from an aluminum die-casting and a lower shell 3 from a fiber composite material. On a ribbed structure of the lower shell 3, an upper end 14 of the reinforcing ribs 9 is preferably configured so as to be widened such that the bearing face between the reinforcing rib 9 and the upper shell 2 is enlarged and, on account thereof, the strength of the axle carrier 1 produced is increased.

Abstract: The present disclosure relates to a method for producing a shaped sheet metal component from a billet by means of U O forming, wherein firstly a preform is created by the U-forming and then a final shaping is performed by the O forming to give a final form.

Abstract: A process for preparing the compound of formula I comprising: a) coupling a compound of formula 2 wherein a leaving group O—SO2—R is selected from the triflate group, the tosylate group, the mesylate group, the besylate group, the nosylate group or the brosylate group, with a suitable boronic acid, a trifluoroborate or a boronic acid ester under argon condition and in the presence of a catalyst and a base in a suitable solvent and then isolating the product as an acid addition salt to afford the compound of formula Ia and b) converting the acid addition salt of formula Ia wherein the acid HX comprises suitable organic or inorganic acids into the compound of formula I by treatment with at least a stoichiometric equivalent of a suitable base.

Abstract: The invention relates to a method for machining a sheet-metal profile 1, wherein the sheet-metal profile 1 is trimmed in a multi-stage cutting process and a cutting edge 2 is produced. Here, pre-cutting is firstly performed on the sheet-metal profile 1, whereby a free space 3 is generated. Stamping of the sheet-metal profile 1 is subsequently performed, wherein the thickness d of the sheet-metal profile 1 along the cutting edge 2 to be produced is reduced. Subsequently, the cutting finishing of the sheet-metal profile 1 is performed, wherein, in particular, cutting is performed in the opposite direction to the stamping of the outline of the finished contour, and the cutting edge 2 is generated.

Abstract: An axle carrier for a motor vehicle is disclosed having at least two attachment points, a metallic upper shell and a lower shell of fiber composite material coupled to the metallic upper shell. A first load path extending through the metallic upper shell between the at least two attachment points in an edge region, and a second load path shorter that the first load path extending through the lower shell.

Abstract: The invention relates to small molecule imaging tools.

Abstract: The invention relates to small molecule imaging tools.

Abstract: The present invention relates to an axle carrier 1 and to a method for the production of the axle carrier 1. The axle carrier 1 has an upper shell 2 from an aluminum die-casting and a lower shell 3 from a fiber composite material. On a ribbed structure of the lower shell 3, an upper end 14 of the reinforcing ribs 9 is preferably configured so as to be widened such that the bearing face between the reinforcing rib 9 and the upper shell 2 is enlarged and, on account thereof, the strength of the axle carrier 1 produced is increased.

Abstract: The invention relates to compounds of formula I: and to pharmaceutically acceptable acid addition salts thereof, wherein R1-R6, Ra, and Rb have any of the values defined in the specification. The compounds are suitable as imaging tools.

Abstract: The present invention relates to compounds that may be used for binding and imaging tau aggregates and related beta-sheet aggregates including, besides others, beta-amyloid aggregates or alpha-synuclein aggregates.

Abstract: The disclosure relates to a method for producing a shaped sheet metal part from a billet by UO forming. First, a preform is created by the U-forming. Then, final forming to give a final form is carried out by the O-forming. The preform has in cross section a maximum width that is smaller than the maximum width of the final form produced after the O-forming.

Abstract: An axle carrier for an electric motor vehicle and a method of manufacturing thereof is disclosed. The axle carrier has a shell component including an upper shell and a lower shell made from a fiber-composite material, and at least one induction line is integrated in the lower shell.

Abstract: The present invention relates to compounds that may be used for binding and imaging tau aggregates and related beta-sheet aggregates including, besides others, beta-amyloid aggregates or alpha-synuclein aggregates.

Abstract: The present invention relates to compounds that may be used for binding and imaging tau aggregates and related beta-sheet aggregates including, for example, beta-amyloid aggregates or alpha-synuclein aggregates.