Patents by Inventor Matthias Kraemer
Matthias Kraemer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140012248Abstract: A medical treatment device includes an elongate member having an internal volume, a proximal end, and a distal end, the internal volume extending from the proximal end to the distal end. The medical treatment device further includes a first coupler and a second coupler, the first coupler and the second coupler coupled to the internal volume of the elongate member; a first joining member and a second joining member, the first joining member coupled to the first coupler and the second joining member coupled to the second coupler. The first joining member is configured to attach to a first biological matter location, and the second joining member is configured to attach to a second biological matter location, the second location being distal to the first location. The second coupler is configured for manipulation to align relative the first coupler such that the second biological matter location relocates adjacent the first biological matter location.Type: ApplicationFiled: April 8, 2013Publication date: January 9, 2014Inventors: Stefan Josef Matthias Kraemer, Robert L. Wilcox, Thomas James Clement
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Patent number: 8361006Abstract: A blood treatment device has a blood purification element divided into two chambers by a semipermeable membrane. With the device, nonphysiological conditions of the patient, in particular critical potassium concentrations and withdrawal rates, can be better prevented during the blood treatment. The device's analyzer unit determines on the basis of at least one sensor the concentration of a substance in the blood in the blood inlet line, the instantaneous transfer rate of this substance through the membrane, and the total quantity of this substance withdrawn during the treatment. The determined concentration is compared with a first admissible value range, the transfer rate is compared with a second admissible value range, and the quantity of the substance withdrawn is compared with a third value range. The device's control unit can instruct the device such that the blood treatment device performs the blood treatment while maintaining all three admissible value ranges.Type: GrantFiled: May 20, 2010Date of Patent: January 29, 2013Assignee: Fresenius Medical Care Deutschland GmbHInventor: Matthias Kraemer
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Publication number: 20110218476Abstract: A medical treatment device includes an elongate member having an internal volume, a proximal end, and a distal end, the internal volume extending from the proximal end to the distal end. The medical treatment device further includes a first coupler and a second coupler, the first coupler and the second coupler coupled to the internal volume of the elongate member; a first joining member and a second joining member, the first joining member coupled to the first coupler and the second joining member coupled to the second coupler. The first joining member is configured to attach to a first biological matter location, and the second joining member is configured to attach to a second biological matter location, the second location being distal to the first location. The second coupler is configured for manipulation to align relative the first coupler such that the second biological matter location relocates adjacent the first biological matter location.Type: ApplicationFiled: February 11, 2011Publication date: September 8, 2011Inventors: Stefan Josef Matthias Kraemer, Robert L. Wilcox, Thomas James Clement
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Patent number: 7999100Abstract: A method for chiral inversion of optically pure or optically enriched mixtures of (S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (I) and (R)-(?)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (II).Type: GrantFiled: July 13, 2005Date of Patent: August 16, 2011Assignee: Bial-Portela CA & S.A.Inventors: David Alexander Learmonth, Günter Weingaertner, Matthias Kraemer
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Publication number: 20110077575Abstract: This invention relates to the field of blood treatment devices having a blood purification element (1) which is divided into two chambers by a semipermeable membrane (3). Such devices are used as hemodialysis machines in artificial kidney therapy. This invention improves upon such a blood treatment device to the extent that nonphysiological conditions of the patient, in particular critical potassium concentrations and withdrawal rates can be better prevented during the blood treatment.Type: ApplicationFiled: May 20, 2010Publication date: March 31, 2011Inventor: Matthias Kraemer
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Patent number: 7834177Abstract: A process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (1) by ring opening of 11a,10b-dihydro-6H-dibenz/b,f/oxireno[d]azepine-6-carboxamide (5), characterised in that the ring opening is carried out under conditions of elevated pressure.Type: GrantFiled: January 13, 2006Date of Patent: November 16, 2010Assignee: Bial - Portela & CA, S.A.Inventors: David Alexander Learmonth, Günter Weingärtner, Matthias Kraemer
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Patent number: 7704213Abstract: A measurement method for determining the blood flow rate QF in blood carrying lines is provided. It may be used in particular to determine the blood flow in a patient's vessel, which is connected to the extracorporeal circulation of a blood treatment machine by an arterial line and a venous line. According to the method, the net rate dX/dt of a variable X is determined, with X being derived from a physicochemical variable Y of the blood with the help of values YA and YV which are adequately constant over time and which respectively characterize the physicochemical property in the arterial line and the venous line during the measurement interval. The net rate dX/dt is then used to determine the blood flow rate QF. The targeted use of indicators is not necessary.Type: GrantFiled: December 4, 2003Date of Patent: April 27, 2010Assignee: Fresenius Medical Care Deutschland GmbHInventor: Matthias Kraemer
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Patent number: 7674235Abstract: A dialyzer having a hemo-dialyzer and/or a hemo-filter and an extra-corporal blood circulation with which a device for the adding of citrate to the blood is connected upstream and a device for the adding of a substitution solution containing ions to the blood is connected downstream of the hemo-dialyzer and/or of the hemo-filter. Ion concentration in the dialyzate downstream of the hemo-dialyzer and/or of the hemo-filter is detected with respect to the direction of flow of the dialyzate. The concentration of the ion, atom or molecule to be determined is reliably ascertained by preventing the complexing of the ion, atom or molecule, at least during the determination of the concentration, by the addition or withdrawal of a substance.Type: GrantFiled: June 9, 2005Date of Patent: March 9, 2010Assignee: Fresenuis Medical Care Deutschland GmbHInventors: Volker Nier, Matthias Kraemer
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Patent number: 7640829Abstract: A drive unit for a motor vehicle, having an engine unit and an axle differential arranged on the engine unit, as well as having drive shafts for the vehicle wheels disposed at least partially in the crankcase. The separating plane between the crankcase bottom part and the oil bearing housing of the crankcase acts as the bearing for at least one drive shaft.Type: GrantFiled: March 9, 2006Date of Patent: January 5, 2010Assignee: Dr. Ing. h.c. F. Porsche AktiengesellschaftInventors: Christian Apel, Matthias Kraemer, Dieter Kraxner, Joachim Esser, Klaus Tiede, Ralph-Maria Netzker, Robert Fuchs
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Publication number: 20080293934Abstract: A method for chiral inversion of optically pure or optically enriched mixtures of (S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (I) and (R)-(?)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (II).Type: ApplicationFiled: July 13, 2005Publication date: November 27, 2008Inventors: David Alexander Learmonth, Gunter Weingaertner, Matthias Kraemer
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Publication number: 20080139807Abstract: A process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (1) by ring opening of 11a,10b-dihydro-6H-dibenz/b,f/oxireno[d]azepine-6-carboxamide (5), characterised in that the ring opening is carried out under conditions of elevated pressure.Type: ApplicationFiled: January 13, 2006Publication date: June 12, 2008Applicant: PORTELA & C.A.,S.A.Inventors: David Alexander Learmonth, Gunter Weingartner, Matthias Kraemer
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Publication number: 20070135750Abstract: This invention relates to the field of blood treatment devices having a blood purification element (1) which is divided into two chambers by a semipermeable membrane (3). Such devices are used as hemodialysis machines in artificial kidney therapy. This invention improves upon such a blood treatment device to the extent that nonphysiological conditions of the patient, in particular critical potassium concentrations and withdrawal rates can be better prevented during the blood treatment.Type: ApplicationFiled: August 2, 2004Publication date: June 14, 2007Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventor: Matthias Kraemer
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Patent number: 7133716Abstract: A device and method are provided for determining the volume ECVhydr(t) of a body compartment of a patient at a time t by conducting measurements at the time t of the patient to determine at least one anthropometric measure X(t), the extracellular water volume ECV(t), and the intracellular water volume ICV (t) of the patient. The extracellular water volume ECVbasic(t) of a first compartment with weight Wbasic(t) of the patient at the time t is derived by using X (t), the extracellular water volume ECVsec(t) of a second compartment of the patient at the time t is derived by using ICV (t), and ECVhydr(t) as the extracellular water volume of a third compartment of the patient is derived with weight Whydr(t). The extracellular volume ECVhydr(t) is a measure for the hydration status of the patient.Type: GrantFiled: December 12, 2001Date of Patent: November 7, 2006Assignee: Fresenius Medical Care Deutschland GmbHInventors: Matthias Kraemer, Paul Chamney
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Publication number: 20060204374Abstract: A drive unit for a motor vehicle, having an engine unit and an axle differential arranged on the engine unit, as well as having drive shafts for the vehicle wheels disposed at least partially in the crankcase. The separating plane between the crankcase bottom part and the oil bearing housing of the crankcase acts as the bearing for at least one drive shaft.Type: ApplicationFiled: March 9, 2006Publication date: September 14, 2006Applicant: Dr. Ing. h.c.F. Porsche AktiengesellschaftInventors: Christian Apel, Matthias Kraemer, Dieter Kraxner, Joachim Esser, Klaus Tiede, Ralph-Maria Netzker, Robert Fuchs
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Publication number: 20060064025Abstract: This invention relates to the field of measurement methods for determining the blood flow rate QF in blood carrying lines (40). It may be used in particular to determine the blood flow in a patient's vessel, which is connected to the extracorporeal circulation (2) of a blood treatment machine by an arterial line (14) and a venous line (15). According to this invention, the net rate dX/dt of a variable X which is derived from a physicochemical variable Y of the blood with the help of values YA and YV which are adequately constant over time, these values characterizing the physicochemical property in the arterial line (14) and the venous line (15) during the measurement interval. The net rate dX/dt is then used to determine the blood flow rate QF. The targeted use of indicators is not necessary.Type: ApplicationFiled: December 4, 2003Publication date: March 23, 2006Inventor: Matthias Kraemer
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Publication number: 20050236330Abstract: A dialyser having a haemo-dialyser and/or a haemo-filter and an extra-corporal blood circulation with which a device for the adding of citrate to the blood is connected upstream and a device for the adding of a substitution solution containing ions to the blood is connected downstream of the haemo-dialyser and/or of the haemo-filter. Ion concentration in the dialysate downstream of the haemo-dialyser and/or of the haemo-filter is detected with respect to the direction of flow of the dialysate. The concentration of the ion, atom or molecule to be determined is reliably ascertained by preventing the complexing of the ion, atom or molecule, at least during the determination of the concentration, by the addition or withdrawal of a substance.Type: ApplicationFiled: June 9, 2005Publication date: October 27, 2005Inventors: Volker Nier, Matthias Kraemer
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Patent number: 6911007Abstract: A method for determining the concentration of an ion, atom or molecule bound in a complex. A reliable determination of the concentration of the ion, atom or molecule to be determined is possible in accordance with the invention in that the complexing of the ion, atom or molecule is prevented at least during the determination of the concentration by the addition or withdrawal of a substance. Also contemplated is a dialyser having a haemo-dialyser and/or a haemo-filter and an extra-corporal blood circulation with which a device for the adding of citrate to the blood is connected upstream and a device for the adding of a substitution solution containing ions to the blood is connected downstream of the haemo-dialyser and/or of the haemo-filter. Ion concentration in the dialysate downstream of the haemo-dialyser and/or of the haemo-filter is detected with respect to the direction of flow of the dialysate.Type: GrantFiled: December 26, 2001Date of Patent: June 28, 2005Assignee: Fresenius Medical Care Deutschland GmbHInventors: Volker Nier, Matthias Kraemer
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Publication number: 20050039763Abstract: The invention makes use of a certain compartmental model to relate various measurement data from a patient to these compartments which in turn enable conclusions about the hydration and/or nutrition status of the patient to be drawn. According to the invention a method is provided for determining the volume ECVhydr(t) of a body compartment of a patient at a time t comprising the steps of determining at least one anthropometric measure X(t) of the patient at the time t, determining the extracellular water volume ECV(t) of the patient at the time t, determining the intracellular water volume ICV(t) of the patient at the time t, deriving the extracellular water volume ECVbasic(t) of a first compartment with weight Wbasic(t) of the patient at the time t by using X(t), deriving the extracellular water volume ECVsec(t) of a second compartment of the patient at the time t by using ICV(t), and deriving ECVhydr(t) as the extracellular water volume of a third compartment of the patient with weight Whydr(t).Type: ApplicationFiled: December 12, 2001Publication date: February 24, 2005Inventors: Matthias Kraemer, Paul Chamney
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Patent number: 6616764Abstract: A method for cleaning an interior of a coating booth is proposed in which blast air is used as at least one of the means for cleaning. For primary cleaning of the coating booth, blast air and corresponding suction operations are used, whereby blowing and suction can be carried out simultaneously, cyclically or sequentially. The invention also relates to a coating booth. The floor and/or the ceiling of the coating booth are formed by a separate floor part and/or a ceiling part which are movable relative to the peripheral wall. The floor part and/or the ceiling part include a cleaning device which can optionally be integrated with the respective floor part and/or ceiling part. The floor part and/or the ceiling part hence operate as a cleaning device for the coating booth. The cleaning device can be displaced in the interior space of the coating booth in a longitudinal direction.Type: GrantFiled: October 30, 2001Date of Patent: September 9, 2003Assignee: Nordson CorporationInventors: Erich Krämer, Matthias Krämer
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Patent number: 6602424Abstract: To increase the safety of an extracorporeal blood treatment machine which has control of the ultrafiltration rate as a function of the blood volume of the patient, the ultrafiltration rate UFR(t) during the treatment is monitored in a safety device. The safety device has a computer unit for determining an upper limit for the ultrafiltration rate UFRlim from the predetermined total ultrafiltrate volume UFVtot and the predetermined treatment time UFT. The safety device also has a monitoring unit with which the ultrafiltration rate is limited to the upper limit determined by the computer unit so that any risk to the patient is prevented even in the case of faulty blood volume control.Type: GrantFiled: December 22, 1999Date of Patent: August 5, 2003Assignee: Fresenius Medical Care Deutschland GmbHInventors: Matthias Krämer, Carsten Müller, Christian Johner