Patents by Inventor Matthias Löhn

Matthias Löhn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted isoquinoline and isoquinolinone derivatives
    Patent number: 8772492
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: July 8, 2014
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Katrin Lorenz, Jochen Goerlitzer, Matthias Lohn
  • Substituted isoquinoline and isoquinolinone derivatives
    Patent number: 8748614
    Abstract: The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: June 10, 2014
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Armin Hofmeister, Jochen Goerlitzer, Matthias Löhn
  • Cycloalkylamine substituted isoquinolone derivatives
    Patent number: 8742116
    Abstract: The invention relates to 6-substituted isoquinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: June 3, 2014
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Armin Hofmeister, Katrin Lorenz, Joachim Brendel, Matthias Löhn, John Weston
  • Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
    Patent number: 8710077
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: April 29, 2014
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Katrin Lorenz, Jochen Goerlitzer, Matthias Löhn, Sandrine Biscarrat, Fréderic Jeannot, Olivier Duclos
  • Cycloalkylamine substituted isoquinoline derivatives
    Patent number: 8710228
    Abstract: The invention relates to 6-substituted isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: April 29, 2014
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Armin Hofmeister, Dieter Kadereit, Stefan Peukert, Sven Ruf, Matthias Löhn, Peter Monecke, Alexander Schiffer, Aimo Kannt, Markus Kohlmann
  • Substituted isoquinoline and isoquinolinone derivatives
    Patent number: 8461144
    Abstract: A method for the treatment or prevention in a mammal of a disease associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase comprising administering to the mammal in need thereof at least one compound of the formula (I).
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: June 11, 2013
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Armin Hofmeister, Joachim Brendel, Matthias Lohn
  • SUBSTITUTED ISOQUINOLINEAND ISOQUINOLINONE DERIVATIVES
    Publication number: 20120316152
    Abstract: A method for the treatment or prevention in a mammal of a disease associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase comprising administering to the mammal in need thereof at least one compound of the formula (I)
    Type: Application
    Filed: August 15, 2012
    Publication date: December 13, 2012
    Applicant: SANOFI
    Inventors: Oliver Plettenburg, Armin Hofmeister, Joachim Brendel, Matthias Löhn
  • Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase
    Patent number: 8278294
    Abstract: The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: October 2, 2012
    Assignee: Sanofi
    Inventors: Oliver Plettenburg, Armin Hofmeister, Joachim Brendel, Matthias Lohn
  • Substituted isoquinoline and isoquinolinone derivatives
    Publication number: 20100105650
    Abstract: The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: April 29, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver PLETTENBURG, Armin HOFMEISTER, Jochen GOERLITZER, Matthias LÖHN
  • Cycloalkylamine substituted isoquinoline derivatives
    Publication number: 20100081671
    Abstract: The invention relates to 6-substituted isoquinoline derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: April 1, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver PLETTENBURG, Armin HOFMEISTER, Dieter KADEREIT, Stefan PEUKERT, Sven RUF, Matthias LÖHN, Peter MONECKE, Alexander SCHIFFER, Aimo KANNT, Markus KOHLMANN
  • Substituted isoquinoline and isoquinolinone derivatives as inhibitors of RHO-Kinase
    Publication number: 20100063025
    Abstract: The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: March 11, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver PLETTENBURG, Armin HOFMEISTER, Joachim BRENDEL, Matthias Löhn
  • Cycloalkylamine substituted isoquinoline and isoquinolinone derivatives
    Publication number: 20100056553
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: March 4, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver PLETTENBURG, Katrin LORENZ, Jochen GOERLITZER, Matthias Löhn, Sandrine BISCARRAT, Fréderic JEANNOT, Olivier DUCLOS
  • New substituted isoquinoline and isoquinolinone derivatives
    Publication number: 20100056566
    Abstract: The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: March 4, 2010
    Applicant: Sanofi-aventis
    Inventors: Oliver PLETTENBURG, Katrin LORENZ, Jochen GOERLITZER, Matthias Löhn
  • CYCLOALKYLAMINE SUBSTITUTED ISOQUINOLONE DERIVATIVES
    Publication number: 20100056518
    Abstract: The invention relates to 6-substituted isoquinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: March 4, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Oliver PLETTENBURG, Armin HOFMEISTER, Katrin LORENZ, Joachim BRENDEL, Matthias Löhn, John Weston
  • Cycloalkylamine substituted isoquinolone and isoquinolinone derivatives
    Publication number: 20100056568
    Abstract: The invention relates to 6-substituted isoquinoline and isoquinolinone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: March 4, 2010
    Applicant: sanofi-aventis
    Inventors: Oliver PLETTENBURG, Armin Hofmeister, Jochen Goerlitzer, Matthias Löhn