Patents by Inventor MATTHIAS LENGA

MATTHIAS LENGA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240242350
    Abstract: The present invention relates to the technical field of producing artificial contrast-enhanced radiological images by way of machine learning methods.
    Type: Application
    Filed: May 25, 2022
    Publication date: July 18, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventor: Matthias LENGA
  • Publication number: 20240212811
    Abstract: A method for training a machine learning model that is able to establish links between data of different modalities by creating a joint representation. In particular, application of the method to medical data including electronic medical records and medical images and/or other medical data. The trained machine learning model can among others fulfil tasks such as autocompletion of incomplete data, detection of uncertain and/or spurious data, generation of probable data and other tasks.
    Type: Application
    Filed: April 20, 2022
    Publication date: June 27, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Steffen VOGLER, Johannes HOEHNE, Matthias LENGA
  • Publication number: 20240185577
    Abstract: The present invention relates to the technical field of machine learning. Subject matter of the present invention is a novel approach for training a neural network and the use of this approach for the processing of (medical) images.
    Type: Application
    Filed: March 24, 2022
    Publication date: June 6, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Matthias LENGA, Marvin PURTORAB, Thiago RAMOS DOS SANTOS, Jens HOOGE, Veronica CORONA
  • Publication number: 20240153163
    Abstract: The present invention relates to the technical field of producing artificial contrast-enhanced radiological images by way of machine learning methods.
    Type: Application
    Filed: November 29, 2021
    Publication date: May 9, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Matthias LENGA, Marvin PURTORAB
  • Publication number: 20240153037
    Abstract: A method and system for correcting a difference in contrast agent density in a sequence of contrast-enhanced image frames. A reference image frame is defined in the sequence of contrast-enhanced image frames, and segmentation is performed on the reference image frame to determine a location of a region of interest within the reference image frame. The region of interest is a region of the reference image frame that contains contrast agent. Other image frames in the sequence of contrast-enhanced images are corrected based on a difference in contrast agent density/image intensity in the region of interest relative to the region of interest in the reference image frame.
    Type: Application
    Filed: March 3, 2022
    Publication date: May 9, 2024
    Inventors: Sebastian Wild, Frank Michael Weber, Irina Waechter-Stehle, Jochen Peters, Arne Ewald, André Gooßen, Matthias Lenga, Tobias Wissel, David Prater
  • Publication number: 20240070440
    Abstract: Systems, methods, and computer programs disclosed herein relate to training a machine learning model to generate multimodal representations of objects, and to the use of said representations for predictive purposes.
    Type: Application
    Filed: February 23, 2022
    Publication date: February 29, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Johannes HOEHNE, Steffen VOGLER, Matthias LENGA
  • Publication number: 20240050053
    Abstract: The present invention relates to the technical field of producing artificial contrast-enhanced radiological images by way of machine learning methods.
    Type: Application
    Filed: November 29, 2021
    Publication date: February 15, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Matthias LENGA, Marvin PURTORAB
  • Publication number: 20240050054
    Abstract: A method for providing a prediction of a representation of an examination region that was generated using a medical image technique involving a contrast agent may include receiving a first representation in frequency space of an examination region of an examination object, receiving a second representation in the frequency space of the examination region of the examination object, providing the first representation and the second representation as an input to a predictive machine learning model that is configured to provide, as an output, a prediction of a representation in the frequency space of the examination region with an amount of the contrast agent administered during a medical imaging technique, receiving the output of the predictive machine learning model based on the input, and converting the output of the predictive machine learning model to a representation in real space of the examination region of the examination object.
    Type: Application
    Filed: November 29, 2021
    Publication date: February 15, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Matthias LENGA, Marvin PURTORAB
  • Publication number: 20240037920
    Abstract: A system and method for training a machine learning module to provide classification and localization information for an image study. The method includes receiving a current image study. The method includes applying the machine learning module to the current image study to generate a classification result including a prediction for one or more class labels for the current image study using User Interface 104 a classification module of the machine learning module. The method includes receiving, via a user interface, a user input indicating a spatial location corresponding to a predicted class label. The method includes training a localization module of the machine learning module using the user input indicating the spatial location corresponding to the predicted class label.
    Type: Application
    Filed: December 18, 2021
    Publication date: February 1, 2024
    Inventors: MATTHIAS LENGA, AXEL SAALBACH, NICOLE SCHADEWALDT, STEFFEN RENISCH, HEINRICH SCHULZ
  • Patent number: 11880432
    Abstract: Presented are concepts for obtaining a confidence measure for a machine learning model. One such concept process input data with the machine learning model to generate a primary result. It also generate a plurality of modified instances of the input data and processes the plurality of modified instances of the input data with the machine learning model to generate a respective plurality of secondary results. A confidence measure relating to the primary result is determined based on the secondary results.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: January 23, 2024
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Matthias Lenga, Rafael Wiemker, Tobias Klinder, Marten Bergtholdt, Heike Carolus
  • Publication number: 20240021320
    Abstract: A system and method for training a deep learning network with previously read image studies to provide a prioritized worklist of unread image studies. The method includes collecting training data including a plurality of previously read image studies, each of the previously read image studies including a classification of findings and radiologist-specific data. The method includes training the deep learning neural network with the training data to predict an urgency score for reading of an unread image study.
    Type: Application
    Filed: November 11, 2021
    Publication date: January 18, 2024
    Inventors: NICOLE SCHADEWALDT, ROLF JÜRGEN WEESE, MATTHIAS LENGA, AXEL SAALBACH, STEFFEN RENISCH, HEINRICH SCHULZ
  • Publication number: 20240005484
    Abstract: A system and related method for image processing. The system comprises an input (IN) interface for receiving two segmentation maps for an input image. The two segmentation maps (11,12) obtained by respective segmentors, a first segmentor (SEG1) and a second segmentor (SEG2). The first segmentor (SEG1) implements a shape-prior-based segmentation algorithm. The second segmentor (SEG2) implements a segmentation algorithm that is not based on a shape-prior, or at least the second segmentor (SEG2) accounts for one or more shape priors at a lower weight as compared to the first segmentor (SEG1). A differentiator (DIF) configured to ascertain a difference between the two segmentation maps. The system may allow detection of abnormalities.
    Type: Application
    Filed: October 9, 2021
    Publication date: January 4, 2024
    Inventors: CHRISTIAN BUERGER, JENS VON BERG, MATTHIAS LENGA, CRISTIAN LORENZ
  • Publication number: 20230368386
    Abstract: Disclosed herein is a medical system comprising a memory storing machine executable instructions and at least one trained neural network. Each of the at least one neural network is configured for receiving a medical image as input. Each of the at least one trained neural network has been modified to provide hidden layer output. Execution of the machine executable instructions causes the computational system to: receive the medical image; receive the hidden layer output in response to inputting the medical image into each of the at least one trained neural network; provide an anonymized image fingerprint comprising the hidden layer output from each of the at least one trained neural network; and receive an image assessment of the medical image in response to querying a historical image database using the anonymized image fingerprint.
    Type: Application
    Filed: September 10, 2021
    Publication date: November 16, 2023
    Inventors: Karsten Sommer, Matthias Lenga, Axel Saalbach
  • Publication number: 20230360225
    Abstract: The invention provides a method for determining a confidence value for an image segmentation. The method includes obtaining an image, wherein the image comprises a view of an anatomical structure and a model of the anatomical structure is obtained, wherein the model comprises a plurality of nodes. The image is processed to generate a plurality of image segmentation outputs, wherein each image segmentation output comprises a set of values for the view, wherein each value of the set of values is associated with a node of the plurality of nodes of the model. For each node of the model, a confidence value is determined based on the plurality of values corresponding to the node. A confidence map of the anatomical structure is generated based on the confidence value of each node.
    Type: Application
    Filed: December 10, 2020
    Publication date: November 9, 2023
    Inventors: Tobias Wissel, Irina Waechter-Stehle, Scott Holland Settlemier, Frank Michael Weber, Arne Ewald, Matthias Lenga, Jochen Peters, André Goossen, Sebastian Wild
  • Publication number: 20230309936
    Abstract: The present invention relates to a system and a method for automatic verification of a positioning of a medical device with respect to an anatomy of a patient in a medical image. A position of a plurality of reference points in a medical image is detected. Further, a presence and a position of a medical device in the medical image is detected. An expected position of the medical device is determined based on the position of the plurality of reference points, and a measure of a correctness of the positioning of the medical device is provided based on a proximity of the position of the medical device to the expected position of the medical device. The measure of the correctness of the positioning of the medical device is provided.
    Type: Application
    Filed: August 26, 2021
    Publication date: October 5, 2023
    Inventors: AXEL SAALBACH, ILYAS SIRAZITDINOV, LEONHARD STEINMEISTER, HARALD ITTRICH, MATTHIAS LENGA, IVO MATTEO BALTRUSCHAT, MICHAEL GRASS
  • Publication number: 20230126342
    Abstract: A mechanism for determining a score indicative of a success of a segmentation of a 3D image, i.e. a success score. The mechanism proposes to obtain one or more 2D images of different target views of a target object in the 3D image, by processing a segmentation result of the 3D image. (A view of) each 2D image is classified using an automated classifier. The classification results are used to determine a success score, which may indicate, for example, whether, or how closely, the 3D segmentation result represents a ground truth segmentation result with sufficient accuracy, e.g. for clinical decision making.
    Type: Application
    Filed: April 12, 2021
    Publication date: April 27, 2023
    Inventors: Jochen Peters, Matthias Lenga, Tobias Wissel, Irina Waechter-Stehle, Frank Michael Weber, Arne Ewald, André Goossen, Sebastian Wild
  • Publication number: 20230061953
    Abstract: The invention provides a method for refining a mapped surface mesh of a cardiac chamber. The method includes obtaining a mapped surface mesh of the cardiac chamber anatomy, wherein the mapped surface mesh comprises a central region representing a cardiac chamber and an outer region representing a peripheral cardiac structure connected to the cardiac chamber, and wherein the mapped surface mesh comprises a first view of an anatomical landmark within the cardiac chamber, and obtaining image data of a cardiac chamber anatomy of a subject. The central region of the mapped surface mesh is deformed based on a first segmentation algorithm configured according to one or more predetermined shape- constraints and the outer region of the mapped surface mesh is deformed based on a second segmentation algorithm configured according to the image data, thereby generating a deformed outer region. The deformed central region and the deformed outer region are then combined, thereby generating a refined mapped surface mesh.
    Type: Application
    Filed: February 2, 2021
    Publication date: March 2, 2023
    Inventors: Frank Michael Weber, Jochen Peters, Irina Waechter-Stehle, Arne Ewald, Matthias Lenga, André Goossen, Sebastian Wild, Tobias Wissel
  • Publication number: 20230054610
    Abstract: An ultrasound imaging system includes a processor circuit in communication with an ultrasound transducer configured to receive three-dimensional ultrasound data of an anatomy, and generate a target image corresponding to a target image plane of the anatomy, and a plurality of adjacent images corresponding to image planes adjacent to the target image plane along a simulated motion path. The processor circuit is further configured to display the target image, receive a user input representative of a direction of motion along the simulated motion path, and display an adjacent image of the plurality of adjacent images corresponding to the direction of motion. Accordingly, the user can observe the target image in its spatial context by scanning through the target image and one or more adjacent images on the display as if the ultrasound transducer were being scanned along the simulated motion path.
    Type: Application
    Filed: February 22, 2021
    Publication date: February 23, 2023
    Inventors: David Nigel Roundhill, Tobias Klinder, Alexander Schmidt-Richberg, Matthias Lenga, Eliza Teodora Orasanu, Cristian Lorenz
  • Publication number: 20230038965
    Abstract: Presented are concepts for initialising a model for model-based segmentation of an image which use specific landmarks (e.g. detected using other techniques) to initialize the segmentation mesh. Using such an approach, embodiments need not be limited to predefined model transformations, but can initialise a segmentation mesh with arbitrary shape. In this way, embodiments may provide for an image segmentation algorithm that not only delivers a robust surface-based segmentation result but also does so for strongly varying target structure variations (in terms of shape).
    Type: Application
    Filed: February 11, 2021
    Publication date: February 9, 2023
    Inventors: CHRISTIAN BUERGER, TOBIAS KLINDER, JENS VON BERG, ASTRID RUTH FRANZ, MATTHIAS LENGA, CRISTIAN LORENZ
  • Publication number: 20230005158
    Abstract: Some embodiments are directed to a segmentation of medical images. For example, a medical image may be registering to multiple atlas images after which a segmentation function may be applied. Multiple segmentation may be fused into a final overall segmentation. The atlas images may be selected on the basis of high segmentation quality or low registration quality.
    Type: Application
    Filed: December 7, 2020
    Publication date: January 5, 2023
    Inventors: MATTHIAS LENGA, TOBIAS WISSEL, ROLF JUERGEN WEESE