Abstract: A humidifier has a housing with inlet and outlet for a first fluid and inlet and outlet for a second fluid. A plate stack with channel plates sequentially arranged in a stacking direction is arranged in the housing. The channel plates have flow channels for the first and second fluids, respectively, separated by semipermeable membranes. The plate stack has a first end plate arranged at a first end and a second end plate arranged at a second end, wherein the first and second ends face away from each other in stacking direction. The housing has a receiving device interacting with a counter receiving device at the plate stack for supporting and sealing the plate stack in the housing. The counter receiving device extends in a plane normal to the stacking direction and is arranged at the first or second end plate. A plate stack for the humidifier is provided.

Abstract: The present disclosure relates to a securing element for a connector, comprising a securing element body having a receptacle that is designed to encompass at least one rear segment of a cable connector element connected to at least one cable, and having a base running substantially perpendicular to the connection direction of the cable connector element, said base having an opening through which the at least one cable connected to the cable connector element can be guided, wherein the base is designed to positively enclose a cable-side end face of the cable connector element; and wherein the securing element body has at least two snap hooks that extend in the plug-in direction and which in each case have at their free end a latching element, such as a latching lug.

Abstract: An actuator for aviation applications, in particular for adjusting rotor blades in a helicopter, may include an electromechanical drive assembly connected to an output drive via a downstream transmission, where the drive assembly is divided into sub-drives that can be operated independently, and where at least two sub-drives are spatially separated from one another in that the transmission is placed between these sub-drives. The transmission may include at least two harmonic gearings coupled to one another by at least one first coupling element, where a first harmonic gearing is located inside a non-rotating first housing, where a second harmonic gearing is located inside a rotating second housing, and where the second housing is connected to the output drive.

Abstract: A holding and moving device includes a support foot, a bearing arm secured pivotably onto the support foot to form a useful load side section and a weight-side section, a first pivot arm connected to the useful load side section of the bearing arm for attachment of a useful load and/or holding device for a useful load, and a second pivot arm connected to the weight-side section of the bearing arm for attachment of a balance weight. The bearing arm and the first and second pivot arms are connected to one another such that the alignment of the first and second pivot arms are essentially parallel to one another in each position. The second pivot arm and/or the weight-side section are designed such that the weight of the first pivot arm and/or of the useful load side section is balanced in each position of the holding and moving device.

Abstract: The invention relates to a long DH (LDH) cassette comprising a recombinant DH construct comprising at least two DH gene segments encoding at least 10 amino acids of the HCDR3 amino acid sequence, wherein at least one of the DH gene segments is a heterologous DH gene segment; an immunoglobulin heavy chain locus and a transgenic non-human animal comprising the same; and their use in producing an immunoglobulin library with long HCDR3 regions.

Abstract: A drug delivery device (1), comprising a delivery unit (3) including a drug container (6) comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, and a drive unit (4) comprising a pneumatic flow system (74) and a pneumatic pumping system configured to pump air via the pneumatic flow system (74) to a space behind the plunger to generate a gas pressure to advance the plunger in the container during drug delivery. The drug delivery device comprises a sealing adaptor (9) mounted on an end of the drug container facing an outer side of the plunger, the sealing adaptor (9) comprising a sealing plug (23) inserted inside an end of the barrel portion, the sealing plug (23) comprising an orifice (26) configured for pluggable sealing connection to a gas channel connector (40) of the pneumatic flow system.

Abstract: This invention generally relates to the field of somatic gene therapy. The invention provides a nucleic acid construct comprising a transgene encoding a therapeutic protein, a tetracycline-responsive aptazyme sequence, and inverted terminal repeats (ITRs). The nucleic acid construct can be transferred to a subject in need thereof in the form of a viral vector, in particular an adeno-associated virus (AAV) vector. The Tet-responsive aptazyme sequence allows for a tightly controlled expression of the transgene in the subject, thereby avoiding toxic side effects. The nucleic acid construct and the viral vectors comprising same are particularly useful in the treatment of proliferative diseases like cancer.

Abstract: A control system for a medical installation, wherein the control system is configured to control a motorized movement of an installation component. The control system includes a control path and a protection path. The control path is configured to control the motorized movement. The protection path is independent of the control path and configured to monitor the control path with regard to compliance with a safety criterion for the motorized movement. The protection path includes at least one freely programmable microcontroller.

Abstract: Push actuated double fluid dispenser (1), comprising a container (2) having a first cavity (4a) and a second cavity (4b) separated from the cap first cavity (4a), and a dispensing pump device (6) in a general form of a cap assembled to the container over the first and second cavities, the dispensing pump device comprising a base part (7) and a cap part (8) including a pump mechanism (16) comprising an elastic flexible pump membrane (18) manually movable from an uncompressed state to a compressed state.

Abstract: A metering console (100) includes a housing (110) adapted to allow flow of a liquid (F) therethrough. The housing (110) is adapted to attach with one or more gardening devices (132, 152). The metering console (100) includes a display (170) associated with the housing (110). The metering console (100) is characterized in that the display (170) is rotatably engaged with the housing (110) of the metering console (100) such that the display (170) rotates along a central axis (A-A?) of the housing (110).

Abstract: A food cooking appliance for cooking a food product disposed on a substrate is disclosed. The food cooking appliance comprises a gas burner disposed below the substrate. The gas burner includes a plurality of circumferentially spaced flame openings and a radiant disposed above and proximate to the spaced flame openings. Heat generated by flames emanating from the spaced flame openings heats the radiant, causing the radiant to radiate heat, to increase the overall heat transferred to the substrate by the burner.

Abstract: A drug delivery device (1), comprising a delivery unit (3) including a drug container (6), a liquid flow system (7), a pumping system (8), and a casing (9) enclosing therein the drug container, the pumping system and at least a part of the liquid flow system, the drug container comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, the liquid flow system (7) connected fluidically to the drug container during delivery of the liquid drug.

Abstract: Methods, systems, apparatus, and articles of manufacture for monocular depth estimation are disclosed. An example apparatus disclosed herein is to determine bin center positions for a pixel of an image based on first features obtained at a first decoder layer of an encoder-decoder architecture, the image representative of a three-dimensional (3D) scene, the bin center positions corresponding to respective different metric depth values. The example apparatus is also to adjust the bin center positions at a second decoder layer of the encoder-decoder architecture based on an attractor point, the attractor point based on the first features and second features obtained at the second decoder layer. The example apparatus is further to output a metric depth map corresponding to the image, the metric depth map including a metric depth value corresponding to the pixel, the metric depth value based on the adjusted bin center positions.

Abstract: Machine learning models can generate outputs such as salient object detection. However, top-performing large-scale models have high computational cost, making the models hard to deploy on resource-constrained devices and to make predictions in real time. A difference convolution reparameterization technique can be used to fuse the sets of parameters learned during training time into a single set of parameters to be used at inference time or at deployment. The technique can increase performance without adding a lot of parameters. Furthermore, an efficient and effective spatial temporal difference convolution block can be used to leverage temporal information to make predictions. The spatial temporal difference convolution block can also apply the difference convolution reparameterization technique to reduce the need to increase parameters to achieve desired performance.

Abstract: A monitoring system for a travel drive includes a rotational speed sensor of a hydrostatic motor. The rotational speed sensor is configured to determine acceleration. At least one signal from a pressure sensor mounted on at least one working line that connects a pump to the hydrostatic motor of a hydrostatic travel drive is evaluated. The pressure sensor is preferably arranged on at least one working connection of the pump. The system uses the additional pressure signal to evaluate in a reliable manner whether the hydrostatic travel drive generates an unwanted drive torque.

Abstract: A method of producing a machining segment, in which a green body (51) is constructed from a machining zone (54), wherein the machining zone (54) is produced from a first metallic powder material (56) and hard material particles (58), the green body (51) is compacted under pressure with a compression pressure to result in a compact body and the compact body is sintered thermally at a sintering temperature to result in the finished machining segment, wherein the machining zone (54) is produced by layer-by-layer application of material layers of the first metallic powder material (56) and particle layers of the hard material particles (58), wherein the hard material particles (58) in one particle layer are placed into the previously applied material layer of the first metallic powder material (56).

Abstract: The invention relates to a method for automatically examining a liquid sample, which has a liquid and at least one particle, by means of a first measurement signal which emanates from a liquid region and which serves to determine at least one particle with a first property, and by means of a second measurement signal which emanates from the liquid region and serves to determine at least one particle with a second property, the first measurement signal and the second measurement signal being evaluated independently of one another and whether a particle condition has been satisfied in the liquid region subsequently being determined on the basis of the evaluated first measurement signal and the evaluated second measurement signal.

Abstract: A method operates a hearing aid, in particular a classic hearing aid. The hearing aid includes an input transducer, a signal processing device, and an output transducer. Wherein an occurrence of a comb filter effect is determined by the signal processing device, and wherein a countermeasure is controlled by the signal processing device as a function of the determined occurrence of the comb filter effect.

Abstract: Systems, apparatuses and methods may provide for technology that trains a first neural radiance field (NeRF) model with first images corresponding to a first instance of a scene, detects second images corresponding to a second instance of the scene, and applies generative replay and the second images to the first NeRF model to obtain a second NeRF model, wherein one or more of appearance changes or geometry changes in the second instance of the scene relative to the first instance of the scene are incorporated into the second NeRF model.

Abstract: A metering console (100) includes a housing (110) adapted to allow flow of a liquid (F) therethrough. The housing (110) is adapted to attach with one or more gardening devices (132, 152). The metering console (100) includes a display (170) associated with the housing (110). The metering console (100) is characterized in that the display (170) is rotatably engaged with the housing (110) of the metering console (100) such that the display (170) rotates along a central axis (A-A?) of the housing (110).