Abstract: The present disclosure relates to a securing element for a connector, comprising a securing element body having a receptacle that is designed to encompass at least one rear segment of a cable connector element connected to at least one cable, and having a base running substantially perpendicular to the connection direction of the cable connector element, said base having an opening through which the at least one cable connected to the cable connector element can be guided, wherein the base is designed to positively enclose a cable-side end face of the cable connector element; and wherein the securing element body has at least two snap hooks that extend in the plug-in direction and which in each case have at their free end a latching element, such as a latching lug.

Abstract: An actuator for aviation applications, in particular for adjusting rotor blades in a helicopter, may include an electromechanical drive assembly connected to an output drive via a downstream transmission, where the drive assembly is divided into sub-drives that can be operated independently, and where at least two sub-drives are spatially separated from one another in that the transmission is placed between these sub-drives. The transmission may include at least two harmonic gearings coupled to one another by at least one first coupling element, where a first harmonic gearing is located inside a non-rotating first housing, where a second harmonic gearing is located inside a rotating second housing, and where the second housing is connected to the output drive.

Abstract: A holding and moving device includes a support foot, a bearing arm secured pivotably onto the support foot to form a useful load side section and a weight-side section, a first pivot arm connected to the useful load side section of the bearing arm for attachment of a useful load and/or holding device for a useful load, and a second pivot arm connected to the weight-side section of the bearing arm for attachment of a balance weight. The bearing arm and the first and second pivot arms are connected to one another such that the alignment of the first and second pivot arms are essentially parallel to one another in each position. The second pivot arm and/or the weight-side section are designed such that the weight of the first pivot arm and/or of the useful load side section is balanced in each position of the holding and moving device.

Abstract: A data collection device comprises: a first portion having one or more features configured for attaching of the first portion to a dosage knob of an injection device; a second portion rotatably coupled with the first portion, wherein at least part of the second portion is movable axially relative to the first portion; a sensor arrangement configured to detect rotation of the first portion relative to the second portion; and a processor arrangement configured to, based on said detected movement, determine a medicament amount expelled by the injection device, wherein the coupling arrangement is configured to provide a non-permanent coupling between the first portion and the dosage knob of the injection device.

Abstract: A drug delivery device (1), comprising a delivery unit (3) including a drug container (6) comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, and a drive unit (4) comprising a pneumatic flow system (74) and a pneumatic pumping system configured to pump air via the pneumatic flow system (74) to a space behind the plunger to generate a gas pressure to advance the plunger in the container during drug delivery. The drug delivery device comprises a sealing adaptor (9) mounted on an end of the drug container facing an outer side of the plunger, the sealing adaptor (9) comprising a sealing plug (23) inserted inside an end of the barrel portion, the sealing plug (23) comprising an orifice (26) configured for pluggable sealing connection to a gas channel connector (40) of the pneumatic flow system.

Abstract: This invention generally relates to the field of somatic gene therapy. The invention provides a nucleic acid construct comprising a transgene encoding a therapeutic protein, a tetracycline-responsive aptazyme sequence, and inverted terminal repeats (ITRs). The nucleic acid construct can be transferred to a subject in need thereof in the form of a viral vector, in particular an adeno-associated virus (AAV) vector. The Tet-responsive aptazyme sequence allows for a tightly controlled expression of the transgene in the subject, thereby avoiding toxic side effects. The nucleic acid construct and the viral vectors comprising same are particularly useful in the treatment of proliferative diseases like cancer.

Abstract: Push actuated double fluid dispenser (1), comprising a container (2) having a first cavity (4a) and a second cavity (4b) separated from the cap first cavity (4a), and a dispensing pump device (6) in a general form of a cap assembled to the container over the first and second cavities, the dispensing pump device comprising a base part (7) and a cap part (8) including a pump mechanism (16) comprising an elastic flexible pump membrane (18) manually movable from an uncompressed state to a compressed state.

Abstract: A data collection device comprises: a first portion having one or more features configured for attaching of the first portion to a dosage knob of an injection device; a second portion rotatably coupled with the first portion, wherein at least part of the second portion is movable axially relative to the first portion; a sensor arrangement configured to detect rotation of the first portion relative to the second portion; and a processor arrangement configured to, based on said detected movement, determine a medicament amount expelled by the injection device, wherein the coupling arrangement is configured to provide a non-permanent coupling between the first portion and the dosage knob of the injection device.

Abstract: A metering console (100) includes a housing (110) adapted to allow flow of a liquid (F) therethrough. The housing (110) is adapted to attach with one or more gardening devices (132, 152). The metering console (100) includes a display (170) associated with the housing (110). The metering console (100) is characterized in that the display (170) is rotatably engaged with the housing (110) of the metering console (100) such that the display (170) rotates along a central axis (A-A?) of the housing (110).

Abstract: A drug delivery device (1), comprising a delivery unit (3) including a drug container (6), a liquid flow system (7), a pumping system (8), and a casing (9) enclosing therein the drug container, the pumping system and at least a part of the liquid flow system, the drug container comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, the liquid flow system (7) connected fluidically to the drug container during delivery of the liquid drug.

Abstract: The invention relates to a method for automatically examining a liquid sample, which has a liquid and at least one particle, by means of a first measurement signal which emanates from a liquid region and which serves to determine at least one particle with a first property, and by means of a second measurement signal which emanates from the liquid region and serves to determine at least one particle with a second property, the first measurement signal and the second measurement signal being evaluated independently of one another and whether a particle condition has been satisfied in the liquid region subsequently being determined on the basis of the evaluated first measurement signal and the evaluated second measurement signal.

Abstract: A method operates a hearing aid, in particular a classic hearing aid. The hearing aid includes an input transducer, a signal processing device, and an output transducer. Wherein an occurrence of a comb filter effect is determined by the signal processing device, and wherein a countermeasure is controlled by the signal processing device as a function of the determined occurrence of the comb filter effect.

Abstract: A metering console (100) includes a housing (110) adapted to allow flow of a liquid (F) therethrough. The housing (110) is adapted to attach with one or more gardening devices (132, 152). The metering console (100) includes a display (170) associated with the housing (110). The metering console (100) is characterized in that the display (170) is rotatably engaged with the housing (110) of the metering console (100) such that the display (170) rotates along a central axis (A-A?) of the housing (110).

Abstract: A high output gas burner such as for a food cooking appliance is disclosed. The gas burner is adapted to combust a mixture of gas and air. The gas burner has a cross ring having a plurality of radially spaced channels and a plurality of axially spaced channels. The radially spaced channels and the axially spaced channels are adapted to guide the air to be combusted with the gas. The radially spaced channels have a diameter of the order of 10 mm and the axially spaced channels have a diameter of the order of 8 mm.

Abstract: An actuator for aviation applications, in particular for adjusting rotor blades in a helicopter, may include an electromechanical drive assembly connected to an output drive via a downstream transmission, where the drive assembly is divided into sub-drives that can be operated independently, and where at least two sub-drives are spatially separated from one another in that the transmission is placed between these sub-drives. The transmission may include at least two harmonic gearings coupled to one another by at least one first coupling element, where a first harmonic gearing is located inside a non-rotating first housing, where a second harmonic gearing is located inside a rotating second housing, and where the second housing is connected to the output drive.

Abstract: The invention relates to a brake piston 1 for a brake caliper 9 of a disk brake, which is produced using working processes from a metallic material, in particular from a flat metal sheet, and is formed in one piece as a unilaterally open pot with a piston longitudinal axis A, with a piston wall 2 and with a piston head 3. There is a need for robust and light as well as alternatively constructed, efficiently producible and well guided brake pistons. The object is achieved firstly in principle on the basis of a cup-shapedly worked brake piston blank 19, in that at least one locally defined, i.e. partially cold-upset or partially ironed, cylindrical piston wall portion is present with a partially deformed piston wall 2 which is configured in adaptively modified manner by plastic material deformation by means of material redistribution (flow) including strain-hardening of its piston wall thickness of sl?x.

Abstract: A method fits a digital hearing aid having an input transducer, a signal processing device and an output transducer. The signal processing device is configured to form an evaluation unit, a comparator unit, and a pre-amplification unit. An acoustic test signal is generated by an external testing device while the hearing aid is worn by a hearing-aid wearer. A digital test input signal is generated by the input transducer on the basis of the acoustic test signal. A sound pressure-dependent test quantity is determined on the basis of the digital test input signal by the evaluation unit. A deviation between the sound pressure-dependent test quantity and a reference quantity stored in the signal processing device is determined by the comparator unit. A pre-amplification by the pre-amplification unit is adjusted on the basis of the determined deviation.

Abstract: A transmitter device (100) includes a housing (102). The transmitter device (100) has a cable (110). The cable (110) is at least partially housed within the housing (102) and electrically connected to a socket (130). Further, the transmitter device (100) has a sensor (106). The sensor (106) is electrically coupled with the cable (110). The transmitter device (100) further includes a cover (104). The cover (104) at least partially covers the sensor (106). The transmitter dev ice (100) is characterized in that the socket (130) is disposed outside the housing (102), and the socket (130) is flexibly coupled to the housing (102) through the cable (110). The housing (102) includes a channel (111) such that the cable (110) is slidably received within the channel (111).

Abstract: A method and microscopy system are useful for recording an image of a sample region. A laser beam is directed onto the sample region with interface(s). An objective lens facilitates images the laser beam on a focusing point which lies on the optical axis of the objective lens or an axis parallel thereto, and which lies in a focusing plane. The objective lens and the sample region are displaced with respect to one another in relative fashion along the optical axis of the objective lens to different relative displacement positions. Intensity values of the laser beam are captured for a respective relative displacement position. A respective highest intensity value for a respective displacement position, a curve of the highest intensity values, and a reference relative displacement position from at least one maximum of the curve, are determined. Image(s) of the sample region is/are captured at the reference relative displacement position.

Abstract: A method for operating a parking lock system (10) with a parking interlock gear (11) is provided. The parking lock system (10) also includes a parking pawl (12) insertable with an insertion section (20) in one of recesses (16) of the parking interlock gear (11) in order to interlock the parking interlock gear (11), a parking lock actuator (13) for the parking pawl (12), and a parking lock sensor (14) for detecting an absolute rotation angle position of the parking interlock gear (11). The method includes detecting an absolute rotation angle position of the parking interlock gear (11) and comparing the detected absolute rotation angle position with a reference rotation angle position. When the particular absolute rotation angle position is situated behind the reference rotation angle position as viewed in the particular direction of rotation of the parking interlock gear (11), a rattling process of the parking pawl (12) is detected.